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Elevated serum YKL-40 levels in patients with Kawasaki disease

Authors
 K. Y. Kim  ;  Y. Ahn  ;  D. Y. Kim  ;  Ho-Seong Kim  ;  D. S. Kim 
Citation
 BIOMARKERS, Vol.22(3-4) : 326-330, 2017 
Journal Title
 BIOMARKERS 
ISSN
 1354-750X 
Issue Date
2017
MeSH
Acute Disease ; Biomarkers/blood ; Case-Control Studies ; Chitinase-3-Like Protein 1/blood* ; Humans ; Inflammation/blood ; Mucocutaneous Lymph Node Syndrome/blood ; Mucocutaneous Lymph Node Syndrome/pathology*
Keywords
Kawasaki disease ; YKL-40 ; acute phase reactant
Abstract
CONTEXT: YKL-40 is an inflammatory biomarker for endothelial dysfunction that may have a role in Kawasaki disease (KD). OBJECTIVES: We investigated the association of serum YKL-40 levels with KD and established laboratory parameters for YKL-40 levels and other inflammatory markers. METHODS: YKL-40 levels and other inflammatory markers of 23 KD patients, 9 disease control patients and 11 age-matched healthy controls. RESULTS: YKL-40 concentration in the serum of KD patients significantly increased during the acute disease phase compared with those of disease controls and healthy controls. CONCLUSIONS: Increased YKL-40 levels may provide a useful inflammatory marker for patients with KD
Full Text
http://www.tandfonline.com/doi/full/10.1080/1354750X.2016.1265000
DOI
10.1080/1354750X.2016.1265000
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아청소년과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Dermatology (피부과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Kyu Yeun(김규연)
Kim, Do Young(김도영) ORCID logo https://orcid.org/0000-0002-0194-9854
Kim, Dong Soo(김동수)
Kim, Ho Seong(김호성) ORCID logo https://orcid.org/0000-0003-1135-099X
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/154579
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