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Clinical application of 3D-printed-step-bolus in post-total-mastectomy electron conformal therapy

DC FieldValueLanguage
dc.contributor.author김준원-
dc.contributor.author전미진-
dc.contributor.author조윤진-
dc.contributor.author박광우-
dc.contributor.author이익재-
dc.contributor.author최진현-
dc.contributor.author장원석-
dc.date.accessioned2017-11-02T08:30:23Z-
dc.date.available2017-11-02T08:30:23Z-
dc.date.issued2017-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/154544-
dc.description.abstractThe 3D-printed boluses were used during the radiation therapy of the chest wall in six patients with breast cancer after modified radical mastectomy (MRM). We measured the in-vivo skin doses while both conventional and 3D-printed boluses were placed on the chest wall and compared the mean doses delivered to the ipsilateral lung and the heart. The homogeneity and conformity of the dose distribution in the chest wall for both types of boluses were also evaluated. The uniformity index on the chest skin was improved when the 3D-printed boluses were used, with the overall average skin dose being closer to the prescribed one in the former case (-0.47% versus -4.43%). On comparing the dose-volume histogram (DVH), it was found that the 3D-printed boluses resulted in a reduction in the mean dose to the ipsilateral lung by up to 20%. The precision of dose delivery was improved by 3% with the 3D-printed boluses; in contrast, the conventional step bolus resulted in a precision level of 5%. In conclusion, the use of the 3D-printed boluses resulted in better dose homogeneity and conformity to the chest wall as well as the sparing of the normal organs, especially the lung. This suggested that their routine use on the chest wall as a therapeutic approach during post-mastectomy radiation therapy offers numerous advantages over conventional step boluses.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherImpact Journals-
dc.relation.isPartOfONCOTARGET-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAged-
dc.subject.MESHBreast Neoplasms/pathology-
dc.subject.MESHBreast Neoplasms/radiotherapy*-
dc.subject.MESHBreast Neoplasms/surgery-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHMastectomy-
dc.subject.MESHMiddle Aged-
dc.subject.MESHNeoplasm Staging-
dc.subject.MESHPostoperative Care-
dc.subject.MESHRadiometry-
dc.subject.MESHRadiotherapy Dosage-
dc.subject.MESHRadiotherapy Planning, Computer-Assisted-
dc.subject.MESHRadiotherapy, Conformal/methods*-
dc.subject.MESHTreatment Outcome-
dc.subject.MESHTumor Burden-
dc.titleClinical application of 3D-printed-step-bolus in post-total-mastectomy electron conformal therapy-
dc.typeArticle-
dc.publisher.locationUnited States-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Radiation Oncology-
dc.contributor.googleauthorKwangwoo Park-
dc.contributor.googleauthorSungjin Park-
dc.contributor.googleauthorMi-Jin Jeon-
dc.contributor.googleauthorJinhyun Choi-
dc.contributor.googleauthorJun Won Kim-
dc.contributor.googleauthorYoon Jin Cho-
dc.contributor.googleauthorWon-Seok Jang-
dc.contributor.googleauthorYo Sup Keum-
dc.contributor.googleauthorIk Jae Lee-
dc.identifier.doi10.18632/oncotarget.12829-
dc.contributor.localIdA05177-
dc.contributor.localIdA05186-
dc.contributor.localIdA01432-
dc.contributor.localIdA03055-
dc.contributor.localIdA04697-
dc.contributor.localIdA05174-
dc.contributor.localIdA00958-
dc.relation.journalcodeJ02421-
dc.identifier.eissn1949-2553-
dc.identifier.pmid27784001-
dc.subject.keyword3D printer-
dc.subject.keyword3D-printed bolus-
dc.subject.keywordMRM-
dc.subject.keyworddosimetery-
dc.subject.keywordelectron conformal therapy-
dc.contributor.alternativeNameKim, Jun Won-
dc.contributor.alternativeNameJeon, Mi Jin-
dc.contributor.alternativeNameCho, Yoon Jin-
dc.contributor.alternativeNamePark, Kwang Woo-
dc.contributor.alternativeNameLee, Ik Jae-
dc.contributor.alternativeNameChoi, Jinhyun-
dc.contributor.alternativeNameJang, Won Seok-
dc.contributor.affiliatedAuthorJeon, Mi Jin-
dc.contributor.affiliatedAuthorCho, Yoon Jin-
dc.contributor.affiliatedAuthorPark, Kwang Woo-
dc.contributor.affiliatedAuthorLee, Ik Jae-
dc.contributor.affiliatedAuthorChoi, Jinhyun-
dc.contributor.affiliatedAuthorJang, Won Seok-
dc.contributor.affiliatedAuthorKim, Jun Won-
dc.citation.titleOncotarget-
dc.citation.volume8-
dc.citation.number15-
dc.citation.startPage25660-
dc.citation.endPage26558-
dc.identifier.bibliographicCitationONCOTARGET , Vol.8(15) : 25660-26558, 2017-
dc.date.modified2017-11-01-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiation Oncology (방사선종양학교실) > 1. Journal Papers

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