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Abnormal neurodevelopmental outcomes are very likely in cases of bilateral neonatal arterial ischaemic stroke
DC Field | Value | Language |
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dc.contributor.author | 남궁란 | - |
dc.contributor.author | 박국인 | - |
dc.contributor.author | 박민수 | - |
dc.contributor.author | 신정은 | - |
dc.contributor.author | 은호선 | - |
dc.contributor.author | 이순민 | - |
dc.contributor.author | 진주현 | - |
dc.date.accessioned | 2017-11-02T08:27:57Z | - |
dc.date.available | 2017-11-02T08:27:57Z | - |
dc.date.issued | 2017 | - |
dc.identifier.issn | 0803-5253 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/154497 | - |
dc.description.abstract | AIM: Neonatal arterial ischaemic stroke (AIS) is an important cause of severe neurological disability. This study aimed to analyse the clinical manifestations and outcomes of AIS patients. METHODS: We enrolled neonates with AIS admitted to Severance Children's Hospital and Gangnam Severance Hospital between 2008 and 2015. AIS was confirmed using magnetic resonance imaging (MRI). We retrospectively reviewed the clinical manifestations, MRI findings, electroencephalography (EEG) findings and neurodevelopmental outcomes. RESULTS: The study comprised 29 neonates (18 boys). The mean follow-up period was 15.4 months (range 6-44 months), and the mean age at diagnosis was 8.1 days. Seizure was the most common symptom (66%). Bilateral involvement was more common than unilateral involvement (52%). The middle cerebral artery was the most commonly identified territory (79%). Abnormal EEG findings were noted in 93% of the cases. Neurodevelopment was normal in 11 (38%) patients, while cerebral palsy and delayed development were noted in eight (28%) and six (21%) patients, respectively. Patients with bilateral involvement were very likely to have abnormal neurodevelopmental outcomes. CONCLUSION: Our study showed that abnormal neurodevelopmental outcomes were very likely after cases of neonatal AIS with bilateral involvement, and clinicians should consider early and more effective interventions in such cases. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.publisher | Wiley-Blackwell | - |
dc.relation.isPartOf | ACTA PAEDIATRICA | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Cerebral Infarction/complications* | - |
dc.subject.MESH | Cerebral Infarction/diagnostic imaging | - |
dc.subject.MESH | Child, Preschool | - |
dc.subject.MESH | Electroencephalography | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Infant | - |
dc.subject.MESH | Infant, Newborn | - |
dc.subject.MESH | Magnetic Resonance Imaging | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Neurodevelopmental Disorders/diagnostic imaging | - |
dc.subject.MESH | Neurodevelopmental Disorders/etiology* | - |
dc.subject.MESH | Neuroimaging | - |
dc.subject.MESH | Retrospective Studies | - |
dc.title | Abnormal neurodevelopmental outcomes are very likely in cases of bilateral neonatal arterial ischaemic stroke | - |
dc.type | Article | - |
dc.publisher.location | Norway | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Pediatrics | - |
dc.contributor.googleauthor | Ju Hyun Jin | - |
dc.contributor.googleauthor | Jeong Eun Shin | - |
dc.contributor.googleauthor | Soon Min Lee | - |
dc.contributor.googleauthor | Ho Seon Eun | - |
dc.contributor.googleauthor | Min Soo Park | - |
dc.contributor.googleauthor | Kook In Park | - |
dc.contributor.googleauthor | Ran Namgung | - |
dc.identifier.doi | 10.1111/apa.13655 | - |
dc.contributor.localId | A01438 | - |
dc.contributor.localId | A01468 | - |
dc.contributor.localId | A02152 | - |
dc.contributor.localId | A02635 | - |
dc.contributor.localId | A02905 | - |
dc.contributor.localId | A05188 | - |
dc.contributor.localId | A01241 | - |
dc.relation.journalcode | J00029 | - |
dc.identifier.eissn | 1651-2227 | - |
dc.identifier.pmid | 27809371 | - |
dc.identifier.url | http://onlinelibrary.wiley.com/doi/10.1111/apa.13655/abstract | - |
dc.subject.keyword | Abnormal neurodevelopmental outcome | - |
dc.subject.keyword | Arterial ischaemic stroke | - |
dc.subject.keyword | Bilateral involvement | - |
dc.subject.keyword | Cerebral palsy | - |
dc.subject.keyword | Delayed development | - |
dc.contributor.alternativeName | Namgung, Ran | - |
dc.contributor.alternativeName | Park, Kook In | - |
dc.contributor.alternativeName | Park, Min Soo | - |
dc.contributor.alternativeName | Shin, Jeong Eun | - |
dc.contributor.alternativeName | Eun, Ho Seon | - |
dc.contributor.alternativeName | Lee, Soon Min | - |
dc.contributor.alternativeName | Jin, Ju Hyun | - |
dc.contributor.affiliatedAuthor | Park, Kook In | - |
dc.contributor.affiliatedAuthor | Park, Min Soo | - |
dc.contributor.affiliatedAuthor | Shin, Jeong Eun | - |
dc.contributor.affiliatedAuthor | Eun, Ho Seon | - |
dc.contributor.affiliatedAuthor | Lee, Soon Min | - |
dc.contributor.affiliatedAuthor | Jin, Ju Hyun | - |
dc.contributor.affiliatedAuthor | Namgung, Ran | - |
dc.citation.title | Acta Paediatrica | - |
dc.citation.volume | 106 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 229 | - |
dc.citation.endPage | 235 | - |
dc.identifier.bibliographicCitation | ACTA PAEDIATRICA, Vol.106(2) : 229-235, 2017 | - |
dc.date.modified | 2017-11-01 | - |
dc.identifier.rimsid | 43070 | - |
dc.type.rims | ART | - |
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