Cited 29 times in
The left middle temporal gyrus in the middle of an impaired social-affective communication network in social anxiety disorder
DC Field | Value | Language |
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dc.contributor.author | 김재진 | - |
dc.date.accessioned | 2017-11-02T08:26:59Z | - |
dc.date.available | 2017-11-02T08:26:59Z | - |
dc.date.issued | 2017 | - |
dc.identifier.issn | 0165-0327 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/154480 | - |
dc.description.abstract | BACKGROUND: Previous studies on patients diagnosed with social anxiety disorder (SAD) reported changed patterns of the resting-state functional connectivity network (rs-FCN) between the prefrontal cortices and other prefrontal, amygdalar or striatal regions. Using a graph theory approach, this study explored the modularity-based community profile and patterns of inter-/intra-modular communication for the rs-FCN in SAD. METHODS: In total, for 28 SAD patients and 27 healthy controls (HC), functional magnetic resonance imaging (fMRI) data were acquired in resting-state and subjected to a graph theory analysis. RESULTS: The within-module degree z-score for a hub region [out of a total of 10 hub regions ranked using the participation coefficient] named left middle temporal gyrus was impaired in SAD compared to HC, proportional to the severity of clinician-scored and patient-reported functional impairment in SAD. LIMITATIONS: Most of participants included in this study were undergraduate students in their early-to-mid 20's. CONCLUSIONS: This study showed the importance of functional communication from the left middle temporal gyrus with other opercular-insular-subcortical regions for better objective functioning and lesser subjective disability in SAD. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | English | - |
dc.publisher | Elsevier/North-Holland Biomedical Press | - |
dc.relation.isPartOf | JOURNAL OF AFFECTIVE DISORDERS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Amygdala/physiopathology | - |
dc.subject.MESH | Brain/physiopathology | - |
dc.subject.MESH | Brain Mapping/methods | - |
dc.subject.MESH | Cerebral Cortex/physiopathology | - |
dc.subject.MESH | Corpus Striatum/physiopathology | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Magnetic Resonance Imaging | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Phobia, Social/physiopathology* | - |
dc.subject.MESH | Prefrontal Cortex/physiopathology | - |
dc.subject.MESH | Temporal Lobe/physiopathology* | - |
dc.title | The left middle temporal gyrus in the middle of an impaired social-affective communication network in social anxiety disorder | - |
dc.type | Article | - |
dc.publisher.location | Netherlands | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Psychiatry | - |
dc.contributor.googleauthor | Je-Yeon Yun | - |
dc.contributor.googleauthor | Jae-Chang Kim | - |
dc.contributor.googleauthor | Jeonghun Ku | - |
dc.contributor.googleauthor | Jung-Eun Shin | - |
dc.contributor.googleauthor | Jae-Jin Kim | - |
dc.contributor.googleauthor | Soo-Hee Choi | - |
dc.identifier.doi | 10.1016/j.jad.2017.01.043 | - |
dc.contributor.localId | A00870 | - |
dc.relation.journalcode | J01225 | - |
dc.identifier.eissn | 1573-2517 | - |
dc.identifier.pmid | 28266321 | - |
dc.subject.keyword | Graph theory | - |
dc.subject.keyword | Intra-modular communication | - |
dc.subject.keyword | Left middle temporal gyrus | - |
dc.subject.keyword | Resting state functional connectivity | - |
dc.subject.keyword | Social anxiety disorder | - |
dc.subject.keyword | Social-affective communication network | - |
dc.contributor.alternativeName | Kim, Jae Jin | - |
dc.contributor.affiliatedAuthor | Kim, Jae Jin | - |
dc.citation.title | Journal of Affective Disorders | - |
dc.citation.volume | 214 | - |
dc.citation.startPage | 53 | - |
dc.citation.endPage | 59 | - |
dc.identifier.bibliographicCitation | JOURNAL OF AFFECTIVE DISORDERS, Vol.214 : 53-59, 2017 | - |
dc.date.modified | 2017-11-01 | - |
dc.identifier.rimsid | 43054 | - |
dc.type.rims | ART | - |
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