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Clinical characteristics of complex aortic plaque in patients with non-valvular atrial fibrillation

DC FieldValueLanguage
dc.contributor.author김종윤-
dc.contributor.author김태훈-
dc.contributor.author박희남-
dc.contributor.author양필성-
dc.contributor.author엄재선-
dc.contributor.author이문형-
dc.contributor.author정보영-
dc.date.accessioned2017-11-02T08:17:54Z-
dc.date.available2017-11-02T08:17:54Z-
dc.date.issued2017-
dc.identifier.issn0167-5273-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/154311-
dc.description.abstractBACKGROUND: Although complex aortic plaque (CxAoP) is a component of the CHA2DS2-VASc score in patients with atrial fibrillation (AF), it is underestimated without detection by trans-esophageal echocardiogram (TEE). We have evaluated the incidence and significance of CxAoP among patients with non-valvular AF (NVAF). METHODS: We included 981 patients with NVAF who underwent catheter ablation (59.1±11.1years old, 73.7% male, 70.2% paroxysmal AF). All of the patients underwent pre-procedural TEE evaluation. Left atrial (LA)-cardioembolic (CE) milieu was defined as a dense spontaneous echo-contrast or LA appendage flow velocity≤20cm/s. RESULTS: CxAoP was present in 8.3% of patients, and independently associated with age (OR 1.07, 95% CI 1.03-1.10, p<0.001), male sex (OR 2.34, 95% CI 1.29-4.24, p=0.005), and CHA2DS2-VASc score≥2 (OR 3.33, 95%CI 1.42-7.77, p=0.005). The presence of LA-CE milieu overlapped with CxAoP in only 11% of patients. Patients with CxAoP had a higher prevalence of hypertension (p=0.004), smoking history (p=0.008), paroxysmal AF (PAF, p<0.001), and a smaller LA volume index (p<0.001) than those with LA-CE milieu. The prevalence of persistent AF among patients with a history of stroke was significantly lower in the presence of CxAoP than in those with LA-CE milieu (p=0.014). CHA2DS2-VASc score was underestimated in 11% of high-risk patients (CHA2DS2-VASc score≥2) due to undetected CxAoP. CONCLUSIONS: CxAoP may contribute to the risk of stroke by a different mechanism than LA-CE milieu in patients with NVAF. Imaging assessment for CxAoP affects thromboembolic risk stratification and decision making for stroke prevention in patients with NVAF.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherElsevier-
dc.relation.isPartOfINTERNATIONAL JOURNAL OF CARDIOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAged-
dc.subject.MESHAortic Valve Stenosis/complications*-
dc.subject.MESHAortic Valve Stenosis/diagnosis*-
dc.subject.MESHAtrial Fibrillation/complications*-
dc.subject.MESHAtrial Fibrillation/diagnosis-
dc.subject.MESHAtrial Fibrillation/surgery-
dc.subject.MESHCatheter Ablation-
dc.subject.MESHCohort Studies-
dc.subject.MESHEchocardiography, Transesophageal-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHLogistic Models-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHPlaque, Atherosclerotic/complications*-
dc.subject.MESHPlaque, Atherosclerotic/diagnosis*-
dc.subject.MESHRisk Assessment-
dc.titleClinical characteristics of complex aortic plaque in patients with non-valvular atrial fibrillation-
dc.typeArticle-
dc.publisher.locationNetherlands-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Internal Medicine-
dc.contributor.googleauthorPil-Sung Yang-
dc.contributor.googleauthorTae-Hoon Kim-
dc.contributor.googleauthorJae-Sun Uhm-
dc.contributor.googleauthorJong-Youn Kim-
dc.contributor.googleauthorBoyoung Joung-
dc.contributor.googleauthorMoon-Hyoung Lee-
dc.contributor.googleauthorHui-Nam Pak-
dc.identifier.doi10.1016/j.ijcard.2016.12.075-
dc.contributor.localIdA01085-
dc.contributor.localIdA01776-
dc.contributor.localIdA02323-
dc.contributor.localIdA02337-
dc.contributor.localIdA02766-
dc.contributor.localIdA03609-
dc.contributor.localIdA00926-
dc.relation.journalcodeJ01093-
dc.identifier.eissn1874-1754-
dc.identifier.pmid28038818-
dc.identifier.urlhttp://www.sciencedirect.com/science/article/pii/S0167527316345648-
dc.subject.keywordAtrial fibrillation-
dc.subject.keywordCHA(2)DS(2)-VASc score-
dc.subject.keywordComplex aortic plaque-
dc.contributor.alternativeNameKim, Jong Youn-
dc.contributor.alternativeNameKim, Tae Hoon-
dc.contributor.alternativeNamePak, Hui Nam-
dc.contributor.alternativeNameYang, Pil Sung-
dc.contributor.alternativeNameUhm, Jae Sun-
dc.contributor.alternativeNameLee, Moon Hyoung-
dc.contributor.alternativeNameJoung, Bo Young-
dc.contributor.affiliatedAuthorKim, Tae-Hoon-
dc.contributor.affiliatedAuthorPak, Hui Nam-
dc.contributor.affiliatedAuthorYang, Pil Sung-
dc.contributor.affiliatedAuthorUhm, Jae Sun-
dc.contributor.affiliatedAuthorLee, Moon Hyoung-
dc.contributor.affiliatedAuthorJoung, Bo Young-
dc.contributor.affiliatedAuthorKim, Jong Youn-
dc.citation.titleInternational Journal of Cardiology-
dc.citation.volume230-
dc.citation.startPage85-
dc.citation.endPage90-
dc.identifier.bibliographicCitationINTERNATIONAL JOURNAL OF CARDIOLOGY, Vol.230 : 85-90, 2017-
dc.date.modified2017-11-01-
dc.identifier.rimsid42282-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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