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Prevalence of Metabolic Syndrome in Patients with Schizophrenia in Korea: A Multicenter Nationwide Cross-Sectional Study

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dc.contributor.author김재진-
dc.contributor.author안석균-
dc.date.accessioned2017-11-02T08:16:25Z-
dc.date.available2017-11-02T08:16:25Z-
dc.date.issued2017-
dc.identifier.issn1738-3684-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/154281-
dc.description.abstractOBJECTIVE: We designed a nationwide study with limited exclusion criteria to investigate the prevalence of metabolic syndrome (MetS) in Korea and its relationship with antipsychotic medications. METHODS: This multicenter, cross-sectional, and observational study included patients diagnosed with schizophrenia or schizoaffective disorder. Sixteen hospitals enrolled 845 patients aged 18 to 65 years prescribed any antipsychotic medication between August 2011 and August 2013. MetS was diagnosed using the criteria of the modified Adult Treatment Panel III of the National Cholesterol Education Program with the Korean abdominal obesity definition (waist circumference ≥85 cm in women, ≥90 cm in men). RESULTS: The prevalence of MetS in all patients was 36.5% and was significantly higher in men than women (men, 40.8%; women, 32.2%) and was significantly correlated with age [odds ratio (OR) 1.02] and duration of illness (OR 1.03). The prevalence of MetS across antipsychotic drugs in the major monotherapy group was as follows: 18.8% for quetiapine, 22.0% for aripiprazole, 33.3% for both amisulpride and paliperidone, 34.0% for olanzapine, 35% for risperidone, 39.4% for haloperidol, and 44.7% for clozapine. CONCLUSION: The prevalence of MetS is very high in patients with schizophrenia or schizoaffective disorder. Screening and monitoring of MetS is also strongly recommended.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherKorean Neuropsychiatric Association-
dc.relation.isPartOfPSYCHIATRY INVESTIGATION-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titlePrevalence of Metabolic Syndrome in Patients with Schizophrenia in Korea: A Multicenter Nationwide Cross-Sectional Study-
dc.typeArticle-
dc.publisher.locationKorea (South)-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Psychiatry-
dc.contributor.googleauthorJung Sun Lee-
dc.contributor.googleauthorJun Soo Kwon-
dc.contributor.googleauthorDaeho Kim-
dc.contributor.googleauthorSung-Wan Kim-
dc.contributor.googleauthorJae-Jin Kim-
dc.contributor.googleauthorJong-Hoon Kim-
dc.contributor.googleauthorHee Jung Nam-
dc.contributor.googleauthorSeunghyong Ryu-
dc.contributor.googleauthorIl Ho Park-
dc.contributor.googleauthorSuk Kyoon An-
dc.contributor.googleauthorHong-Seok Oh-
dc.contributor.googleauthorSeunghee Won-
dc.contributor.googleauthorKanguk Lee-
dc.contributor.googleauthorKyu Young Lee-
dc.contributor.googleauthorSeung-Hwan Lee-
dc.contributor.googleauthorYu Sang Lee-
dc.contributor.googleauthorJung-Seo Yi-
dc.contributor.googleauthorKyung Sue Hong-
dc.contributor.googleauthorYeon Ho Joo-
dc.identifier.doi10.4306/pi.2017.14.1.44-
dc.contributor.localIdA02227-
dc.contributor.localIdA00870-
dc.relation.journalcodeJ02569-
dc.identifier.eissn1976-3026-
dc.identifier.pmid28096874-
dc.subject.keywordAntipsychotics-
dc.subject.keywordKorean population-
dc.subject.keywordMetabolic syndrome-
dc.subject.keywordSchizoaffective disorder-
dc.subject.keywordSchizophrenia-
dc.contributor.alternativeNameKim, Jae Jin-
dc.contributor.alternativeNameAn, Suk Kyoon-
dc.contributor.affiliatedAuthorAn, Suk Kyoon-
dc.contributor.affiliatedAuthorKim, Jae Jin-
dc.citation.titlePsychiatry Investigation-
dc.citation.volume14-
dc.citation.number1-
dc.citation.startPage44-
dc.citation.endPage50-
dc.identifier.bibliographicCitationPSYCHIATRY INVESTIGATION, Vol.14(1) : 44-50, 2017-
dc.date.modified2017-11-01-
dc.identifier.rimsid42249-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Psychiatry (정신과학교실) > 1. Journal Papers

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