141 200

Cited 9 times in

Individuality manifests in the dynamic reconfiguration of large-scale brain networks during movie viewing

DC FieldValueLanguage
dc.contributor.author박범희-
dc.contributor.author박해정-
dc.date.accessioned2017-11-02T08:11:49Z-
dc.date.available2017-11-02T08:11:49Z-
dc.date.issued2017-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/154186-
dc.description.abstractIndividuality, the uniqueness that distinguishes one person from another, may manifest as diverse rearrangements of functional connectivity during heterogeneous cognitive demands; yet, the neurobiological substrates of individuality, reflected in inter-individual variations of large-scale functional connectivity, have not been fully evidenced. Accordingly, we explored inter-individual variations of functional connectivity dynamics, subnetwork patterns and modular architecture while subjects watched identical video clips designed to induce different arousal levels. How inter-individual variations are manifested in the functional brain networks was examined with respect to four contrasting divisions: edges within the anterior versus posterior part of the brain, edges with versus without corresponding anatomically-defined structural pathways, inter- versus intra-module connections, and rich club edge types. Inter-subject variation in dynamic functional connectivity occurred to a greater degree within edges localized to anterior rather than posterior brain regions, without adhering to structural connectivity, between modules as opposed to within modules, and in weak-tie local edges rather than strong-tie rich-club edges. Arousal level significantly modulates inter-subject variability in functional connectivity, edge patterns, and modularity, and particularly enhances the synchrony of rich-club edges. These results imply that individuality resides in the dynamic reconfiguration of large-scale brain networks in response to a stream of cognitive demands.-
dc.description.statementOfResponsibilityopen-
dc.formatapplication/pdf-
dc.languageEnglish-
dc.publisherNature Publishing Group-
dc.relation.isPartOfSCIENTIFIC REPORTS-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleIndividuality manifests in the dynamic reconfiguration of large-scale brain networks during movie viewing-
dc.typeArticle-
dc.publisher.locationEngland-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Life Science-
dc.contributor.googleauthorChangwon Jang-
dc.contributor.googleauthorElizabeth Quattrocki Knight-
dc.contributor.googleauthorChongwon Pae-
dc.contributor.googleauthorBumhee Park-
dc.contributor.googleauthorShin-Ae Yoon-
dc.contributor.googleauthorHae-Jeong Park-
dc.identifier.doi10.1038/srep41414-
dc.contributor.localIdA01730-
dc.contributor.localIdA01472-
dc.relation.journalcodeJ02646-
dc.identifier.eissn2045-2322-
dc.identifier.pmid28112247-
dc.contributor.alternativeNamePark, Bum Hee-
dc.contributor.alternativeNamePark, Hae Jeong-
dc.contributor.affiliatedAuthorPark, Hae Jeong-
dc.contributor.affiliatedAuthorPark, Bum Hee-
dc.citation.titleScientific Reports-
dc.citation.volume7-
dc.citation.startPage41414-
dc.identifier.bibliographicCitationSCIENTIFIC REPORTS, Vol.7 : 41414, 2017-
dc.date.modified2017-11-01-
Appears in Collections:
1. College of Medicine (의과대학) > BioMedical Science Institute (의생명과학부) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Nuclear Medicine (핵의학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.