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Relative Prevalence and Antimicrobial Susceptibility of Clinical Isolates of Elizabethkingia Species Based on 16S rRNA Gene Sequencing

DC FieldValueLanguage
dc.contributor.author구남수-
dc.contributor.author용동은-
dc.contributor.author이경원-
dc.contributor.author정석훈-
dc.contributor.author최준용-
dc.date.accessioned2017-11-02T08:08:44Z-
dc.date.available2017-11-02T08:08:44Z-
dc.date.issued2017-
dc.identifier.issn0095-1137-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/154130-
dc.description.abstractSome of the previously reported clinical isolates of Elizabethkingia meningoseptica may be later named species of Elizabethkingia We determined the accuracy of species identification (with two matrix-assisted laser desorption ionization-time of flight mass spectrometry [MALDI-TOF MS] systems and the Vitek 2 GN card), relative prevalence of three Elizabethkingia spp. in clinical specimens, and antimicrobial susceptibility of the species identified by 16S rRNA gene sequencing. Specimens for culture were collected from patients in a university hospital in Seoul, South Korea, between 2009 and 2015. All 3 Elizabethkingia spp. were detected in patients; among the 86 isolates identified by 16S rRNA gene sequencing, 17 (19.8%) were E. meningoseptica, 18 (20.9%) were Elizabethkingia miricola, and 51 (59.3%) were Elizabethkingia anophelis Only the MALDI-TOF Vitek MS system with an amended database correctly identified all of the isolates. The majority (76.7%) of the isolates were from the lower respiratory tract, and 8 (9.3%) were from blood. Over 90% of E. meningoseptica and E. anophelis isolates were susceptible to piperacillin-tazobactam and rifampin. In contrast, all E. miricola isolates were susceptible to fluoroquinolones except ciprofloxacin. Further studies are urgently needed to determine the optimal antimicrobial agents for the treatment of infections due to each individual Elizabethkingia species.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherAmerican Society for Microbiology-
dc.relation.isPartOfJournal of Clinical Microbiology-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAged-
dc.subject.MESHAnti-Bacterial Agents/pharmacology*-
dc.subject.MESHBacteriological Techniques/methods*-
dc.subject.MESHDNA, Bacterial/chemistry-
dc.subject.MESHDNA, Bacterial/genetics-
dc.subject.MESHDNA, Ribosomal/chemistry-
dc.subject.MESHDNA, Ribosomal/genetics-
dc.subject.MESHFemale-
dc.subject.MESHFlavobacteriaceae/classification-
dc.subject.MESHFlavobacteriaceae/drug effects*-
dc.subject.MESHFlavobacteriaceae/genetics-
dc.subject.MESHFlavobacteriaceae/isolation & purification*-
dc.subject.MESHFlavobacteriaceae Infections/epidemiology*-
dc.subject.MESHFlavobacteriaceae Infections/microbiology*-
dc.subject.MESHGenes, rRNA-
dc.subject.MESHHospitals, University-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHPrevalence-
dc.subject.MESHRNA, Ribosomal, 16S/genetics-
dc.subject.MESHRepublic of Korea/epidemiology-
dc.subject.MESHSequence Analysis, DNA-
dc.subject.MESHSpectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization/methods*-
dc.titleRelative Prevalence and Antimicrobial Susceptibility of Clinical Isolates of Elizabethkingia Species Based on 16S rRNA Gene Sequencing-
dc.typeArticle-
dc.publisher.locationUnited States-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Internal Medicine-
dc.contributor.googleauthorMi-Soon Han-
dc.contributor.googleauthorHyunsoo Kim-
dc.contributor.googleauthorYangsoon Lee-
dc.contributor.googleauthorMyungsook Kim-
dc.contributor.googleauthorNam Su Ku-
dc.contributor.googleauthorJun Yong Choi-
dc.contributor.googleauthorDongeun Yong-
dc.contributor.googleauthorSeok Hoon Jeong-
dc.contributor.googleauthorKyungwon Lee-
dc.contributor.googleauthorYunsop Chong-
dc.identifier.doi10.1128/JCM.01637-16-
dc.contributor.localIdA02423-
dc.contributor.localIdA02649-
dc.contributor.localIdA03619-
dc.contributor.localIdA04191-
dc.contributor.localIdA00189-
dc.relation.journalcodeJ01325-
dc.identifier.pmid27847376-
dc.subject.keyword16S rRNA gene sequencing-
dc.subject.keywordElizabethkingia anophelis-
dc.subject.keywordElizabethkingia meningoseptica-
dc.subject.keywordElizabethkingia miricola-
dc.subject.keywordantimicrobial susceptibility-
dc.contributor.alternativeNameKu, Nam Su-
dc.contributor.alternativeNameYong, Dong Eun-
dc.contributor.alternativeNameLee, Kyung Won-
dc.contributor.alternativeNameJeong, Seok Hoon-
dc.contributor.alternativeNameChoi, Jun Yong-
dc.contributor.affiliatedAuthorYong, Dong Eun-
dc.contributor.affiliatedAuthorLee, Kyung Won-
dc.contributor.affiliatedAuthorJeong, Seok Hoon-
dc.contributor.affiliatedAuthorChoi, Jun Yong-
dc.contributor.affiliatedAuthorKu, Nam Su-
dc.citation.titleJournal of Clinical Microbiology-
dc.citation.volume55-
dc.citation.number1-
dc.citation.startPage274-
dc.citation.endPage280-
dc.identifier.bibliographicCitationJournal of Clinical Microbiology, Vol.55(1) : 274-280, 2017-
dc.date.modified2017-11-01-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers

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