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Risk factors for Pneumocystis jirovecii pneumonia (PJP) in kidney transplantation recipients

DC FieldValueLanguage
dc.contributor.author김명수-
dc.contributor.author김세규-
dc.contributor.author김송이-
dc.contributor.author김순일-
dc.contributor.author김영삼-
dc.contributor.author박무석-
dc.contributor.author이수환-
dc.contributor.author이주한-
dc.contributor.author장준-
dc.contributor.author주동진-
dc.contributor.author허규하-
dc.date.accessioned2017-11-01T08:40:38Z-
dc.date.available2017-11-01T08:40:38Z-
dc.date.issued2017-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/153511-
dc.description.abstractPneumocystis jirovecii pneumonia (PJP) is a potentially life-threatening infection that occurs in immunocompromised patients. The aim of this study was to evaluate risk factors for PJP in kidney transplantation recipients. We conducted a retrospective analysis of patient data from 500 consecutive kidney transplants performed at Severance Hospital between April 2011 and April 2014. Eighteen kidney transplantation recipients (3.6%) were diagnosed with PJP. In the univariate analysis, acute graft rejection, CMV infection, use of medication for diabetes mellitus, and lowest lymphocyte count were associated with PJP. Recipients who experienced acute graft rejection (odds ratio [OR] 11.81, 95% confidence interval [CI] 3.06-45.57, P < 0.001) or developed CMV infection (OR 5.42, 95% CI 1.69-17.39, P = 0.005) had high odds of PJP in multivariate analysis. In the acute graft rejection subgroup, patients treated with anti-thymocyte globulin (ATG) had significantly higher odds of PJP (OR 5.25, 95% CI 1.01-27.36, P = 0.006) than those who were not. Our data suggest that acute graft rejection and CMV infection may be risk factors for PJP in kidney transplant patients. The use of ATG for acute graft rejection may increase the risk of PJP.-
dc.description.statementOfResponsibilityopen-
dc.formatapplication/pdf-
dc.languageEnglish-
dc.publisherNature Publishing Group-
dc.relation.isPartOfSCIENTIFIC REPORTS-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleRisk factors for Pneumocystis jirovecii pneumonia (PJP) in kidney transplantation recipients-
dc.typeArticle-
dc.publisher.locationEngland-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Surgery-
dc.contributor.googleauthorSu Hwan Lee-
dc.contributor.googleauthorKyu Ha Huh-
dc.contributor.googleauthorDong Jin Joo-
dc.contributor.googleauthorMyoung Soo Kim-
dc.contributor.googleauthorSoon Il Kim-
dc.contributor.googleauthorJuhan Lee-
dc.contributor.googleauthorMoo Suk Park-
dc.contributor.googleauthorYoung Sam Kim-
dc.contributor.googleauthorSe Kyu Kim-
dc.contributor.googleauthorJoon Chang-
dc.contributor.googleauthorYu Seun Kim-
dc.contributor.googleauthorSong Yee Kim-
dc.identifier.doi10.1038/s41598-017-01818-w-
dc.contributor.localIdA00602-
dc.contributor.localIdA00626-
dc.contributor.localIdA00649-
dc.contributor.localIdA04901-
dc.contributor.localIdA00707-
dc.contributor.localIdA01457-
dc.contributor.localIdA02904-
dc.contributor.localIdA03163-
dc.contributor.localIdA03472-
dc.contributor.localIdA03948-
dc.contributor.localIdA04344-
dc.contributor.localIdA00424-
dc.relation.journalcodeJ02646-
dc.identifier.eissn2045-2322-
dc.identifier.pmid28484270-
dc.contributor.alternativeNameKim, Myoung Soo-
dc.contributor.alternativeNameKim, Se Kyu-
dc.contributor.alternativeNameKim, Song Yi-
dc.contributor.alternativeNameKim, Soon Il-
dc.contributor.alternativeNameKim, Seung Woo-
dc.contributor.alternativeNameKim, Young Sam-
dc.contributor.alternativeNamePark, Moo Suk-
dc.contributor.alternativeNameLee, Su Whan-
dc.contributor.alternativeNameLee, Ju Han-
dc.contributor.alternativeNameChang, Joon-
dc.contributor.alternativeNameJoo, Dong Jin-
dc.contributor.alternativeNameHuh, Kyu Ha-
dc.contributor.affiliatedAuthorKim, Se Kyu-
dc.contributor.affiliatedAuthorKim, Song Yi-
dc.contributor.affiliatedAuthorKim, Soon Il-
dc.contributor.affiliatedAuthorKim, Seung Woo-
dc.contributor.affiliatedAuthorKim, Young Sam-
dc.contributor.affiliatedAuthorPark, Moo Suk-
dc.contributor.affiliatedAuthorLee, Su Whan-
dc.contributor.affiliatedAuthorLee, Ju Han-
dc.contributor.affiliatedAuthorChang, Joon-
dc.contributor.affiliatedAuthorJoo, Dong Jin-
dc.contributor.affiliatedAuthorHuh, Kyu Ha-
dc.contributor.affiliatedAuthorKim, Myoung Soo-
dc.citation.titleScientific Reports-
dc.citation.volume7-
dc.citation.number1-
dc.citation.startPage1571-
dc.identifier.bibliographicCitationSCIENTIFIC REPORTS, Vol.7(1) : 1571, 2017-
dc.date.modified2017-11-01-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Neurology (신경과학교실) > 1. Journal Papers

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