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Feasibility of test-bolus DCE-MRI using CAIPIRINHA-VIBE for the evaluation of pancreatic malignancies

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dc.contributor.author서니은-
dc.date.accessioned2017-10-26T08:06:22Z-
dc.date.available2017-10-26T08:06:22Z-
dc.date.issued2016-
dc.identifier.issn0938-7994-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/152961-
dc.description.abstractOBJECTIVES: To evaluate the feasibility of test-bolus dynamic contrast-enhanced (DCE) MRI with CAIPIRINHA-VIBE for pancreatic malignancies. METHODS: Thirty-two patients underwent DCE-MRI with CAIPIRINHA-VIBE after injection of 2 mL gadolinium. From the resulting time-intensity curve (TIC), we estimated the arterial (AP) and portal venous phase (PVP) scan timing for subsequent multiphasic MRI. DCE-MRI perfusion maps were generated, and perfusion parameters were calculated. The image quality was rated on a 5-point scale (1: poor, 5: excellent). Goodness-of-fit of the TIC was evaluated by Pearson's χ2 test. RESULTS: Test-bolus DCE-MRIs with high temporal (3 s) and spatial resolution (1?×?1?×?4 mm3) were acquired with good-quality perfusion maps of Ktrans and iAUC (mean score 4.313?±?0.535 and 4.125?±?0.554, respectively). The mean χ2 values for fitted TICs were 0.115?±?0.082 for the pancreatic parenchyma and 0.784?±?0.074 for pancreatic malignancies, indicating an acceptable goodness-of-fit. Test-bolus DCE-MRI was highly accurate in estimating the proper timing of AP (90.6 %) and PVP (100 %) of subsequent multiphasic MRI. Between pancreatic adenocarcinomas and neuroendocrine tumours, there were significant differences in the Ktrans (0.073?±?0.058 vs. 0.308?±?0.062, respectively; p?=?0.007) and iAUC (1.501?±?0.828 vs. 3.378?±?0.378, respectively; p?=?0.045). CONCLUSIONS: Test-bolus DCE-MRI using CAIPIRINHA-VIBE is feasible for incorporating perfusion analysis of pancreatic tumours into routine multiphasic MRI. KEY POINTS: ? Test-bolus DCE-MRI using CAIPIRINHA-VIBE is feasible for perfusion analysis of pancreatic tumours. ? CAIPIRINHA-VIBE enables DCE-MRI with high temporal and spatial resolution. ? Test-bolus DCE-MRI is highly accurate in estimating the proper timing of multiphasic MRI.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherSpringer International-
dc.relation.isPartOfEuropean Radiology-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleFeasibility of test-bolus DCE-MRI using CAIPIRINHA-VIBE for the evaluation of pancreatic malignancies-
dc.typeArticle-
dc.publisher.locationGermany-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Radiology-
dc.contributor.googleauthorJimi Huh-
dc.contributor.googleauthorYoonseok Choi-
dc.contributor.googleauthorDong-Cheol Woo-
dc.contributor.googleauthorNieun Seo-
dc.contributor.googleauthorBohyun Kim-
dc.contributor.googleauthorChang Kyung Lee-
dc.contributor.googleauthorIn Seong Kim-
dc.contributor.googleauthorDominik Nickel-
dc.contributor.googleauthorKyung Won Kim-
dc.identifier.doi10.1007/s00330-016-4209-6-
dc.contributor.localIdA01874-
dc.relation.journalcodeJ00851-
dc.identifier.pmid26809293-
dc.identifier.urlhttps://link.springer.com/article/10.1007%2Fs00330-016-4209-6-
dc.contributor.alternativeNameSeo, Nieun-
dc.contributor.affiliatedAuthorSeo, Nieun-
dc.citation.volume26-
dc.citation.number11-
dc.citation.startPage3949-
dc.citation.endPage3956-
dc.identifier.bibliographicCitationEuropean Radiology, Vol.26(11) : 3949-3956, 2016-
dc.date.modified2017-10-24-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers

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