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Preoperative Magnetic Resonance Imaging and Survival Outcomes in T1-2 Breast Cancer Patients Who Receive Breast-Conserving Therapy

DC FieldValueLanguage
dc.contributor.author김승일-
dc.contributor.author박세호-
dc.contributor.author박형석-
dc.date.accessioned2017-10-26T08:02:25Z-
dc.date.available2017-10-26T08:02:25Z-
dc.date.issued2016-
dc.identifier.issn1738-6756-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/152858-
dc.description.abstractPURPOSE: The purpose of the study was to evaluate the effect of preoperative magnetic resonance imaging (MRI) on survival outcomes for breast cancer. METHODS: A total of 954 patients who had T1-2 breast cancer and received breast-conserving therapy (BCT) between 2007 and 2010 were enrolled. We divided the patients according to whether they received preoperative MRI or not. Survival outcomes, including locoregional recurrence-free survival (LRRFS), recurrence-free survival (RFS), and overall survival (OS), were analyzed. RESULTS: Preoperative MRI was performed in 743 of 954 patients. Clinicopathological features were not significantly different between patients with and without preoperative MRI. In the univariate analyses, larger tumors were marginally associated with poor LRRFS compared to smaller tumors (hazard ratio [HR], 3.22; p=0.053). Tumor size, histologic grade, estrogen receptor (ER), progesterone receptor (PR), hormonal therapy, and adjuvant chemotherapy status were associated with RFS. Larger tumor size, higher histologic grade, lack of ER and PR expression, and no hormonal therapy were associated with decreased OS. Tumor size was associated with LRRFS in the multivariate analyses (HR, 4.19; p=0.048). However, preoperative MRI was not significantly associated with LRRFS, RFS, or OS in either univariate or multivariate analyses. CONCLUSION: Preoperative MRI did not influence survival outcomes in T1-2 breast cancer patients who underwent BCT. Routine use of preoperative MRI in T1-2 breast cancer may not translate into longer RFS and OS.-
dc.description.statementOfResponsibilityopen-
dc.languageKorean, English-
dc.publisherKorean Breast Cancer Society-
dc.relation.isPartOfJOURNAL OF BREAST CANCER-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titlePreoperative Magnetic Resonance Imaging and Survival Outcomes in T1-2 Breast Cancer Patients Who Receive Breast-Conserving Therapy-
dc.typeArticle-
dc.publisher.locationKorea (South)-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Surgery-
dc.contributor.googleauthorJaegyu Ryu-
dc.contributor.googleauthorHyung Seok Park-
dc.contributor.googleauthorSanghwa Kim-
dc.contributor.googleauthorJee Ye Kim-
dc.contributor.googleauthorSeho Park-
dc.contributor.googleauthorSeung Il Kim-
dc.identifier.doi10.4048/jbc.2016.19.4.423-
dc.contributor.localIdA01524-
dc.contributor.localIdA01753-
dc.contributor.localIdA00658-
dc.relation.journalcodeJ01279-
dc.identifier.eissn2092-9900-
dc.relation.journalsince2005~-
dc.identifier.pmid28053631-
dc.relation.journalbefore~2004 Journal of Korean Breast Cancer Society (한국유방암학회지)-
dc.contributor.alternativeNameKim, Seung Il-
dc.contributor.alternativeNamePark, Se Ho-
dc.contributor.alternativeNamePark, Hyung Seok-
dc.contributor.affiliatedAuthorPark, Se Ho-
dc.contributor.affiliatedAuthorPark, Hyung Seok-
dc.contributor.affiliatedAuthorKim, Seung Il-
dc.citation.volume19-
dc.citation.number4-
dc.citation.startPage423-
dc.citation.endPage428-
dc.identifier.bibliographicCitationJOURNAL OF BREAST CANCER, Vol.19(4) : 423-428, 2016-
dc.date.modified2017-10-24-
dc.identifier.rimsid40487-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers

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