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Successful treatment of tubulointerstitial nephritis and uveitis with steroid and azathioprine in a 12-year-old boy
DC Field | Value | Language |
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dc.contributor.author | 김지은 | - |
dc.contributor.author | 김지홍 | - |
dc.contributor.author | 신재일 | - |
dc.contributor.author | 정현주 | - |
dc.date.accessioned | 2017-10-26T08:01:34Z | - |
dc.date.available | 2017-10-26T08:01:34Z | - |
dc.date.issued | 2016 | - |
dc.identifier.issn | 1738-1061 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/152840 | - |
dc.description.abstract | Tubulointerstitial nephritis and uveitis (TINU) syndrome is a rare disease, often underdiagnosed or misdiagnosed in children. We describe the case of a 12-year-old boy who presented to Severance Hospital with a 1-month history of bilateral conjunctival injection. He was first evaluated by an Ophthalmologist in another hospital and diagnosed with panuveitis. Laboratory tests indicated renal failure, and a renal biopsy confirmed the diagnosis of acute tubulointerstitial nephritis. An extensive exclusion of all possible causes allowed a diagnosis of TINU syndrome. The patient was treated with a systemic corticosteroid (initially prednisolone, 2 mg/kg and later deflazacort 1 mg/kg) and topical steroid drops for 1 month. Azathioprine was later added to the treatment regimen and the systemic steroid was slowly tapered. The final outcome of renal-ocular disease was favorable in the patient. However, long-term follow-up is necessary to properly manage frequent relapses and incomplete renal recovery. TINU should be considered as a differential diagnosis in children with uveitis or acute renal failure. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | Korean | - |
dc.publisher | 대한소아과학회 | - |
dc.relation.isPartOf | Korean Journal of Pediatrics | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Successful treatment of tubulointerstitial nephritis and uveitis with steroid and azathioprine in a 12-year-old boy | - |
dc.type | Article | - |
dc.publisher.location | Korea | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Pediatrics | - |
dc.contributor.googleauthor | Ji Eun Kim | - |
dc.contributor.googleauthor | Se Jin Park | - |
dc.contributor.googleauthor | Ji Young Oh | - |
dc.contributor.googleauthor | Hyeon Joo Jeong | - |
dc.contributor.googleauthor | Ji Hong Kim | - |
dc.contributor.googleauthor | Jae Il Shin | - |
dc.identifier.doi | 10.3345/kjp.2016.59.11.S99 | - |
dc.contributor.localId | A04913 | - |
dc.contributor.localId | A01003 | - |
dc.contributor.localId | A02142 | - |
dc.contributor.localId | A03771 | - |
dc.relation.journalcode | J02100 | - |
dc.identifier.eissn | 2092-7258 | - |
dc.relation.journalsince | 2004~ | - |
dc.identifier.pmid | 28018458 | - |
dc.relation.journalbefore | ~2003 Korean Journal of Pediatrics | - |
dc.subject.keyword | Azathioprine | - |
dc.subject.keyword | Steroids | - |
dc.subject.keyword | Tubulointerstitial nephritis and uveitis | - |
dc.contributor.alternativeName | Kim, Ji Eun | - |
dc.contributor.alternativeName | Kim, Ji Hong | - |
dc.contributor.alternativeName | Shin, Jae Il | - |
dc.contributor.alternativeName | Jeong, Hyeon Joo | - |
dc.contributor.affiliatedAuthor | Kim, Ji Eun | - |
dc.contributor.affiliatedAuthor | Kim, Ji Hong | - |
dc.contributor.affiliatedAuthor | Shin, Jae Il | - |
dc.contributor.affiliatedAuthor | Jeong, Hyeon Joo | - |
dc.citation.volume | 59 | - |
dc.citation.number | Suppl. 1 | - |
dc.citation.startPage | 99 | - |
dc.citation.endPage | 102 | - |
dc.identifier.bibliographicCitation | Korean Journal of Pediatrics, Vol.59(Suppl. 1) : 99-102, 2016 | - |
dc.date.modified | 2017-10-24 | - |
dc.identifier.rimsid | 40470 | - |
dc.type.rims | ART | - |
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