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Successful treatment of tubulointerstitial nephritis and uveitis with steroid and azathioprine in a 12-year-old boy

DC Field Value Language
dc.contributor.author김지은-
dc.contributor.author김지홍-
dc.contributor.author신재일-
dc.contributor.author정현주-
dc.date.accessioned2017-10-26T08:01:34Z-
dc.date.available2017-10-26T08:01:34Z-
dc.date.issued2016-
dc.identifier.issn1738-1061-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/152840-
dc.description.abstractTubulointerstitial nephritis and uveitis (TINU) syndrome is a rare disease, often underdiagnosed or misdiagnosed in children. We describe the case of a 12-year-old boy who presented to Severance Hospital with a 1-month history of bilateral conjunctival injection. He was first evaluated by an Ophthalmologist in another hospital and diagnosed with panuveitis. Laboratory tests indicated renal failure, and a renal biopsy confirmed the diagnosis of acute tubulointerstitial nephritis. An extensive exclusion of all possible causes allowed a diagnosis of TINU syndrome. The patient was treated with a systemic corticosteroid (initially prednisolone, 2 mg/kg and later deflazacort 1 mg/kg) and topical steroid drops for 1 month. Azathioprine was later added to the treatment regimen and the systemic steroid was slowly tapered. The final outcome of renal-ocular disease was favorable in the patient. However, long-term follow-up is necessary to properly manage frequent relapses and incomplete renal recovery. TINU should be considered as a differential diagnosis in children with uveitis or acute renal failure.-
dc.description.statementOfResponsibilityopen-
dc.languageKorean-
dc.publisher대한소아과학회-
dc.relation.isPartOfKorean Journal of Pediatrics-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleSuccessful treatment of tubulointerstitial nephritis and uveitis with steroid and azathioprine in a 12-year-old boy-
dc.typeArticle-
dc.publisher.locationKorea-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Pediatrics-
dc.contributor.googleauthorJi Eun Kim-
dc.contributor.googleauthorSe Jin Park-
dc.contributor.googleauthorJi Young Oh-
dc.contributor.googleauthorHyeon Joo Jeong-
dc.contributor.googleauthorJi Hong Kim-
dc.contributor.googleauthorJae Il Shin-
dc.identifier.doi10.3345/kjp.2016.59.11.S99-
dc.contributor.localIdA04913-
dc.contributor.localIdA01003-
dc.contributor.localIdA02142-
dc.contributor.localIdA03771-
dc.relation.journalcodeJ02100-
dc.identifier.eissn2092-7258-
dc.relation.journalsince2004~-
dc.identifier.pmid28018458-
dc.relation.journalbefore~2003 Korean Journal of Pediatrics-
dc.subject.keywordAzathioprine-
dc.subject.keywordSteroids-
dc.subject.keywordTubulointerstitial nephritis and uveitis-
dc.contributor.alternativeNameKim, Ji Eun-
dc.contributor.alternativeNameKim, Ji Hong-
dc.contributor.alternativeNameShin, Jae Il-
dc.contributor.alternativeNameJeong, Hyeon Joo-
dc.contributor.affiliatedAuthorKim, Ji Eun-
dc.contributor.affiliatedAuthorKim, Ji Hong-
dc.contributor.affiliatedAuthorShin, Jae Il-
dc.contributor.affiliatedAuthorJeong, Hyeon Joo-
dc.citation.volume59-
dc.citation.numberSuppl. 1-
dc.citation.startPage99-
dc.citation.endPage102-
dc.identifier.bibliographicCitationKorean Journal of Pediatrics, Vol.59(Suppl. 1) : 99-102, 2016-
dc.date.modified2017-10-24-
dc.identifier.rimsid40470-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아과학교실) > 1. Journal Papers

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