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소아에서 혈청 25-hydroxyvitamin D와 알레르기비염의 연관성

DC FieldValueLanguage
dc.contributor.author김경원-
dc.contributor.author김규언-
dc.contributor.author김윤희-
dc.contributor.author김정윤-
dc.contributor.author박영아-
dc.contributor.author설인숙-
dc.contributor.author손명현-
dc.contributor.author윤서희-
dc.date.accessioned2017-10-26T07:57:39Z-
dc.date.available2017-10-26T07:57:39Z-
dc.date.issued2016-
dc.identifier.issn2288-0402-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/152746-
dc.description.abstractPurpose: Vitamin D is known to play an important role in the regulation of the immune system and in the prevention of allergic disease. Herein, we examined the association between vitamin D and allergic rhinitis (AR) in children. Methods: A total of 72 aeroallergen-proven AR and 57 healthy control subjects who visited Severance Children’s Hospital between 2012 and 2014 were evaluated. The mean serum 25-hydroxyvitamin D (25(OH)D) level was measured in all subjects to evaluate their vitamin D status. Results: The mean serum 25(OH)D levels was significantly lower in patients with AR than in controls (19.5±6.4 ng/mL vs. 22.3±5.8 ng/mL, P=0.013). The incidence of AR is higher in the 25(OH)D-insufficient group (15?20 ng/mL) and in the 25(OH)D-deficient group (≤15 ng/mL) compared with the 25(OH)D-sufficient group (>20 ng/mL) (40.3% vs. 84.4% vs. 22.2%, P<0.001). There was no significant difference in the serum 25(OH)D level between subgroups with mild and moderate-to-severe AR symptoms (19.8±6.5 vs. 19.0±6.3, P=0.596). After adjusting for confounding factors, the lower serum vitamin D level groups had increased odds of AR compared with the 25(OH)D-sufficient group (odds ration [95% confidence interval]; 3.67 [1.29?10.38] in the 25(OH)D-insufficient group; P=0.014 and 6.04 [1.49?24.51] in the 25(OH)D-deficient group; P=0.012). Conclusion: The serum vitamin D levels were significantly lower in children with AR compared with healthy controls. Therefore, lower serum level of 25(OH)D may be associated with the development of AR.-
dc.description.statementOfResponsibilityopen-
dc.publisherKorean Academy of Pediatric Allergy and Respiratory Disease-
dc.relation.isPartOfALLERGY ASTHMA & RESPIRATORY DISEASE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.title소아에서 혈청 25-hydroxyvitamin D와 알레르기비염의 연관성-
dc.title.alternativeAssociation between the serum 25-hydroxyvitamin D level and allergic rhinitis in Korean children-
dc.typeArticle-
dc.publisher.locationKorea-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Pediatrics-
dc.contributor.googleauthor윤서희-
dc.contributor.googleauthor김정윤-
dc.contributor.googleauthor김윤희-
dc.contributor.googleauthor박영아-
dc.contributor.googleauthor설인숙-
dc.contributor.googleauthor김민정-
dc.contributor.googleauthor김경원-
dc.contributor.googleauthor손명현-
dc.contributor.googleauthor김규언-
dc.identifier.doi10.4168/aard.2016.4.6.423-
dc.contributor.localIdA00327-
dc.contributor.localIdA00799-
dc.contributor.localIdA04909-
dc.contributor.localIdA01570-
dc.contributor.localIdA01941-
dc.contributor.localIdA01967-
dc.contributor.localIdA02563-
dc.contributor.localIdA00303-
dc.relation.journalcodeJ00065-
dc.relation.journalsince2013~-
dc.relation.journalbefore~2012 Allergy Asthma & Respiratory Disease (소아알레르기 호흡기학회지)-
dc.contributor.alternativeNameKim, Kyung Won-
dc.contributor.alternativeNameKim, Kyu Earn-
dc.contributor.alternativeNameKim, Yoon Hee-
dc.contributor.alternativeNameKim, Jung Yoon-
dc.contributor.alternativeNamePark, Young A-
dc.contributor.alternativeNameSol, In Suk-
dc.contributor.alternativeNameSon, Myung Hyun-
dc.contributor.alternativeNameYoon, Seo Hee-
dc.contributor.affiliatedAuthorKim, Kyu Earn-
dc.contributor.affiliatedAuthorKim, Yoon Hee-
dc.contributor.affiliatedAuthorKim, Jung Yoon-
dc.contributor.affiliatedAuthorPark, Young A-
dc.contributor.affiliatedAuthorSol, In Suk-
dc.contributor.affiliatedAuthorSon, Myung Hyun-
dc.contributor.affiliatedAuthorYoon, Seo Hee-
dc.contributor.affiliatedAuthorKim, Kyung Won-
dc.citation.volume4-
dc.citation.number6-
dc.citation.startPage423-
dc.citation.endPage428-
dc.identifier.bibliographicCitationALLERGY ASTHMA & RESPIRATORY DISEASE, Vol.4(6) : 423-428, 2016-
dc.date.modified2017-10-24-
dc.identifier.rimsid39754-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아과학교실) > 1. Journal Papers

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