0 509

Cited 66 times in

Rationale and design of the Progression of AtheRosclerotic PlAque DetermIned by Computed TomoGraphic Angiography IMaging (PARADIGM) registry: A comprehensive exploration of plaque progression and its impact on clinical outcomes from a multicenter serial coronary computed tomographic angiography study.

DC Field Value Language
dc.contributor.author이상은-
dc.contributor.author장혁재-
dc.contributor.author정남식-
dc.date.accessioned2017-10-26T07:57:35Z-
dc.date.available2017-10-26T07:57:35Z-
dc.date.issued2016-
dc.identifier.issn0002-8703-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/152744-
dc.description.abstractBACKGROUND: The natural history of coronary artery disease (CAD) in patients with low-to-intermediate risk is not well characterized. Although earlier invasive serial studies have documented the progression of atherosclerotic burden, most were focused on high-risk patients only. The PARADIGM registry is a large, prospective, multinational dynamic observational registry of patients undergoing serial coronary computed tomographic angiography (CCTA). The primary aim of PARADIGM is to characterize the natural history of CAD in relation to clinical and laboratory data. DESIGN: The PARADIGM registry (ClinicalTrials.govNCT02803411) comprises ≥2,000 consecutive patients across 9 cluster sites in 7 countries. PARADIGM sites were chosen on the basis of adequate CCTA volume, site CCTA proficiency, local demographic characteristics, and medical facilities to ensure a broad-based sample of patients. Patients referred for clinically indicated CCTA will be followed up and enrolled if they had a second CCTA scan. Patients will also be followed up beyond serial CCTA performance to identify adverse CAD events that include cardiac and noncardiac death, myocardial infarction, unstable angina, target vessel revascularization, and CAD-related hospitalization. SUMMARY: The results derived from the PARADIGM registry are anticipated to add incremental insight into the changes in CCTA findings in accordance with the progression or regression of CAD that confer prognostic value beyond demographic and clinical characteristics.-
dc.description.statementOfResponsibilityrestriction-
dc.publisherMosby-
dc.relation.isPartOfAMERICAN HEART JOURNAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleRationale and design of the Progression of AtheRosclerotic PlAque DetermIned by Computed TomoGraphic Angiography IMaging (PARADIGM) registry: A comprehensive exploration of plaque progression and its impact on clinical outcomes from a multicenter serial coronary computed tomographic angiography study.-
dc.typeArticle-
dc.publisher.locationUnited States-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Internal Medicine-
dc.contributor.googleauthorSang-Eun Lee-
dc.contributor.googleauthorHyuk-Jae Chang-
dc.contributor.googleauthorAsim Rizvi-
dc.contributor.googleauthorMartin Hadamitzky-
dc.contributor.googleauthorYong-Jin Kim-
dc.contributor.googleauthorEdoardo Conte-
dc.contributor.googleauthorDaniele Andreini-
dc.contributor.googleauthorGianluca Pontone-
dc.identifier.doi10.1016/j.ahj.2016.09.003-
dc.contributor.localIdA03490-
dc.contributor.localIdA03585-
dc.contributor.localIdA02827-
dc.relation.journalcodeJ00069-
dc.identifier.eissn1097-6744-
dc.identifier.pmid27914502-
dc.identifier.urlhttp://www.sciencedirect.com/science/article/pii/S0002870316301983-
dc.contributor.alternativeNameLee, Sang Eun-
dc.contributor.alternativeNameChang, Hyuck Jae-
dc.contributor.alternativeNameChung, Nam Sik-
dc.contributor.affiliatedAuthorChang, Hyuck Jae-
dc.contributor.affiliatedAuthorChung, Nam Sik-
dc.contributor.affiliatedAuthorLee, Sang Eun-
dc.citation.volume182-
dc.citation.startPage72-
dc.citation.endPage79-
dc.identifier.bibliographicCitationAMERICAN HEART JOURNAL, Vol.182 : 72-79, 2016-
dc.date.modified2017-10-24-
dc.identifier.rimsid39752-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.