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Juvenile Myasthenia Gravis in Korea: Subgroup Analysis According to Sex and Onset Age

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dc.contributor.author강훈철-
dc.contributor.author김승민-
dc.contributor.author김흥동-
dc.contributor.author신하영-
dc.contributor.author이영목-
dc.contributor.author이준수-
dc.date.accessioned2017-10-26T07:54:28Z-
dc.date.available2017-10-26T07:54:28Z-
dc.date.issued2016-
dc.identifier.issn0883-0738-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/152676-
dc.description.abstractJuvenile myasthenia gravis presents before 18 years of age with different characteristics according to racial background and pubertal development. The authors aimed to determine the clinical characteristics of children and adolescents of Korean ethnicity with myasthenia gravis, and evaluate the presentation and clinical outcomes according to the sex and onset age of the patients. The authors recruited 88 Korean juvenile myasthenia gravis patients between September 2005 and August 2015. Worse clinical severity from presentation, more aggressive treatment strategies, and worse final treatment outcomes were noted in girls with postpubertal onset than in the other patients. The symptoms were milder (pure ocular presentation in 96.6% [85/88]) and the disease course was more benign (94.3% [83/88]) in this study than in the literature. The homogenous racial background might have contributed to these results. These findings highlight the influence of pubertal development and the need for timely and appropriate active treatment, including thymectomy, to improve prognosis.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherSage-
dc.relation.isPartOfJOURNAL OF CHILD NEUROLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleJuvenile Myasthenia Gravis in Korea: Subgroup Analysis According to Sex and Onset Age-
dc.typeArticle-
dc.publisher.locationUnited States-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Pediatrics-
dc.contributor.googleauthorHa Neul Lee-
dc.contributor.googleauthorHoon-Chul Kang-
dc.contributor.googleauthorJoon Soo Lee-
dc.contributor.googleauthorHeung Dong Kim-
dc.contributor.googleauthorHa Young Shin-
dc.contributor.googleauthorSeung Min Kim-
dc.contributor.googleauthorIl Nam Sunwoo-
dc.contributor.googleauthorYoung-Mock Lee-
dc.identifier.doi10.1177/0883073816666206-
dc.contributor.localIdA00653-
dc.contributor.localIdA01208-
dc.contributor.localIdA02170-
dc.contributor.localIdA02955-
dc.contributor.localIdA03177-
dc.contributor.localIdA00102-
dc.relation.journalcodeJ01311-
dc.identifier.eissn1708-8283-
dc.identifier.pmid27581849-
dc.identifier.urlhttp://journals.sagepub.com/doi/abs/10.1177/0883073816666206-
dc.contributor.alternativeNameKang, Hoon Chul-
dc.contributor.alternativeNameKim, Seung Min-
dc.contributor.alternativeNameKim, Heung Dong-
dc.contributor.alternativeNameShin, Ha Young-
dc.contributor.alternativeNameLee, Young Mock-
dc.contributor.alternativeNameLee, Joon Soo-
dc.contributor.affiliatedAuthorKim, Seung Min-
dc.contributor.affiliatedAuthorKim, Heung Dong-
dc.contributor.affiliatedAuthorShin, Ha Young-
dc.contributor.affiliatedAuthorLee, Young Mock-
dc.contributor.affiliatedAuthorLee, Joon Soo-
dc.contributor.affiliatedAuthorKang, Hoon Chul-
dc.citation.volume31-
dc.citation.number14-
dc.citation.startPage1561-
dc.citation.endPage1568-
dc.identifier.bibliographicCitationJOURNAL OF CHILD NEUROLOGY, Vol.31(14) : 1561-1568, 2016-
dc.date.modified2017-10-24-
dc.identifier.rimsid39685-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurology (신경과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아과학교실) > 1. Journal Papers

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