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Outcomes of uterine sarcoma found incidentally after uterus-preserving surgery for presumed benign disease

DC FieldValueLanguage
dc.contributor.author김상운-
dc.contributor.author김성훈-
dc.contributor.author김영태-
dc.contributor.author김현수-
dc.contributor.author남은지-
dc.contributor.author이정윤-
dc.date.accessioned2017-10-26T07:40:40Z-
dc.date.available2017-10-26T07:40:40Z-
dc.date.issued2016-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/152368-
dc.description.abstractBACKGROUND: The aims of this study were to evaluate the impact of initial uterus-preserving surgery, such as myomectomy or subtotal hysterectomy, on the recurrence rates of patients with uterine sarcoma found incidentally and to investigate the role of surgical re-exploration in this disease subset. METHODS: We performed a retrospective chart review for patients who had previously undergone either total hysterectomy or subtotal hysterectomy or myomectomy at the time of initial surgery for presumed benign uterine leiomyoma and were found to have uterine sarcoma on final pathology. Survival analysis was performed comparing patients according to the type of initial surgery. RESULTS: Between 2006 and 2014, 45 patients with uterine sarcoma were identified. Myomectomy or subtotal hysterectomy was performed in 15 patients, and 30 patients underwent total hysterectomy as the initial surgery. Of the patients who underwent myomectomy or subtotal hysterectomy as the initial surgery (n?=?15), 14 were re-explored to complete staging. Of the patients who underwent re-exploration (n?=?14), five (35.8 %) had remnant sarcoma on the remaining uterus and no patients had disseminated disease. A Kaplan-Meier curve and log-rank test showed no difference in progression-free survival (P?=?0.941) between the two groups. CONCLUSION: Initial uterus-preserving surgery does not appear to be associated with an adverse impact on survival outcomes for unexpected uterine sarcoma when surgical re-exploration was performed immediately. As such, surgical re-exploration may be useful for removing any remnant sarcoma.-
dc.description.statementOfResponsibilityopen-
dc.formatapplication/pdf-
dc.publisherBioMed Central-
dc.relation.isPartOfBMC CANCER-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHFemale-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHHumans-
dc.subject.MESHHysterectomy/adverse effects*-
dc.subject.MESHLaparoscopy-
dc.subject.MESHLeiomyoma/pathology-
dc.subject.MESHLeiomyoma/surgery*-
dc.subject.MESHMiddle Aged-
dc.subject.MESHNeoplasm Staging-
dc.subject.MESHPrognosis-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHSarcoma/epidemiology*-
dc.subject.MESHSarcoma/etiology-
dc.subject.MESHSarcoma/pathology-
dc.subject.MESHSurvival Rate-
dc.subject.MESHUterine Myomectomy/adverse effects*-
dc.subject.MESHUterine Neoplasms/pathology-
dc.subject.MESHUterine Neoplasms/surgery*-
dc.titleOutcomes of uterine sarcoma found incidentally after uterus-preserving surgery for presumed benign disease-
dc.typeArticle-
dc.publisher.locationEngland-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Obstetrics & Gynecology-
dc.contributor.googleauthorJung-Yun Lee-
dc.contributor.googleauthorHyun Soo Kim-
dc.contributor.googleauthorEun Ji Nam-
dc.contributor.googleauthorSang Wun Kim-
dc.contributor.googleauthorSunghoon Kim-
dc.contributor.googleauthorYoung Tae Kim-
dc.identifier.doi10.1186/s12885-016-2727-x-
dc.contributor.localIdA00595-
dc.contributor.localIdA00729-
dc.contributor.localIdA01114-
dc.contributor.localIdA01262-
dc.contributor.localIdA04638-
dc.contributor.localIdA00526-
dc.relation.journalcodeJ00351-
dc.identifier.eissn1471-2407-
dc.relation.journalsince2001~-
dc.identifier.pmid27553655-
dc.subject.keywordEndometrial stromal sarcoma-
dc.subject.keywordLeiomyosarcoma-
dc.subject.keywordMorcellation-
dc.subject.keywordMyomectomy-
dc.subject.keywordSurvival analysis-
dc.contributor.alternativeNameKim, Sang Wun-
dc.contributor.alternativeNameKim, Sung Hoon-
dc.contributor.alternativeNameKim, Young Tae-
dc.contributor.alternativeNameKim, Hyun-Soo-
dc.contributor.alternativeNameNam, Eun Ji-
dc.contributor.alternativeNameLee, Jung-Yun-
dc.contributor.affiliatedAuthorKim, Sung Hoon-
dc.contributor.affiliatedAuthorKim, Young Tae-
dc.contributor.affiliatedAuthorKim, Hyun-Soo-
dc.contributor.affiliatedAuthorNam, Eun Ji-
dc.contributor.affiliatedAuthorLee, Jung-Yun-
dc.contributor.affiliatedAuthorKim, Sang Wun-
dc.citation.volume16-
dc.citation.number1-
dc.citation.startPage675-
dc.identifier.bibliographicCitationBMC CANCER, Vol.16(1) : 675, 2016-
dc.date.modified2017-10-24-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Obstetrics and Gynecology (산부인과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers

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