Cited 14 times in
Reference Intervals of Thromboelastometric Evaluation of Coagulation in Pediatric Patients with Congenital Heart Diseases: A Retrospective Investigation
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 길혜금 | - |
dc.contributor.author | 이종화 | - |
dc.contributor.author | 김지영 | - |
dc.contributor.author | 신유림 | - |
dc.date.accessioned | 2017-10-26T07:37:33Z | - |
dc.date.available | 2017-10-26T07:37:33Z | - |
dc.date.issued | 2016 | - |
dc.identifier.issn | 1234-1010 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/152293 | - |
dc.description.abstract | BACKGROUND Rotational thromboelastometry (ROTEM®) is a point-of-care test for coagulation, enabling physicians to make a swift decision. The aim of this investigation was to establish reference intervals of thromboelastometric evaluation for coagulation in pediatric patients with congenital heart diseases (CHD). MATERIAL AND METHODS As baseline data, 3 assays of ROTEM® (INTEM, EXTEM, and FIBTEM) were measured after anesthesia induction. ROTEM® parameters were clotting time (CT), amplitude at 10 min (A10), clot formation time (CFT), a angle, maximal clot firmness (MCF), clot lysis index at 60 min (LI60), and maximal clot elasticity (MCE). As age is a well-known factor for maturation, age groups were determined as follows; 1) <1 month, 2) 1-3 months, 3) 4-12 months, 4) 1-3 years, 5) 4-6 years, 6) 7-12 years, and 7) 13-16 years. Reference limits representing 95% of distribution of ROTEM® parameters and 90% confidence intervals of upper and lower reference limits were calculated. RESULTS The data of 413 patients were analyzed. Although INTEM CT was prolonged, significantly shorter CT and CFT, steeper α, and greater A10, MCF, and MCE were shown in patients age <3 months compared to older children. CONCLUSIONS Reference intervals of thromboelastometric evaluation for coagulation from pediatric patients with CHD were shown to have similar pattern to those obtained from healthy pediatric patients. Pediatric patients with CHD, even with cyanosis, were demonstrated to have functionally intact coagulation profile before surgery. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | International Scientific Information | - |
dc.relation.isPartOf | MEDICAL SCIENCE MONITOR | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adolescent | - |
dc.subject.MESH | Blood Coagulation/physiology | - |
dc.subject.MESH | Blood Coagulation Tests/methods | - |
dc.subject.MESH | Child | - |
dc.subject.MESH | Child, Preschool | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Heart Defects, Congenital/blood* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Infant | - |
dc.subject.MESH | Infant, Newborn | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Reference Values | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Thrombelastography/methods* | - |
dc.subject.MESH | Thrombelastography/standards | - |
dc.title | Reference Intervals of Thromboelastometric Evaluation of Coagulation in Pediatric Patients with Congenital Heart Diseases: A Retrospective Investigation | - |
dc.type | Article | - |
dc.publisher.location | United States | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Anesthesiology and Pain Medicine | - |
dc.contributor.googleauthor | Ji Young Kim | - |
dc.contributor.googleauthor | Yu Rim Shin | - |
dc.contributor.googleauthor | Hae Keum Kil | - |
dc.contributor.googleauthor | Mi Ran Park | - |
dc.contributor.googleauthor | Jong Wha Lee | - |
dc.identifier.doi | 10.12659/MSM.901256 | - |
dc.contributor.localId | A03154 | - |
dc.contributor.localId | A00977 | - |
dc.contributor.localId | A02128 | - |
dc.contributor.localId | A00283 | - |
dc.relation.journalcode | J03024 | - |
dc.identifier.eissn | 1643-3750 | - |
dc.relation.journalsince | 1995 | - |
dc.identifier.pmid | 27711024 | - |
dc.contributor.alternativeName | Kil, Hae Keum | - |
dc.contributor.alternativeName | Lee, Jong Wha | - |
dc.contributor.alternativeName | Kim, Ji Young | - |
dc.contributor.alternativeName | Shin, Yu Rim | - |
dc.contributor.affiliatedAuthor | Lee, Jong Wha | - |
dc.contributor.affiliatedAuthor | Kim, Ji Young | - |
dc.contributor.affiliatedAuthor | Shin, Yu Rim | - |
dc.contributor.affiliatedAuthor | Kil, Hae Keum | - |
dc.citation.volume | 22 | - |
dc.citation.startPage | 3576 | - |
dc.citation.endPage | 3587 | - |
dc.identifier.bibliographicCitation | MEDICAL SCIENCE MONITOR, Vol.22 : 3576-3587, 2016 | - |
dc.date.modified | 2017-10-24 | - |
dc.identifier.rimsid | 48028 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.