103 193

Cited 8 times in

Eribulin Mesylate Combined with Local Treatment for Brain Metastasis from Breast Cancer: Two Case Reports

DC FieldValueLanguage
dc.contributor.author안성귀-
dc.contributor.author정준-
dc.date.accessioned2017-10-26T07:35:11Z-
dc.date.available2017-10-26T07:35:11Z-
dc.date.issued2016-
dc.identifier.issn1738-6756-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/152227-
dc.description.abstractThe prognosis associated with brain metastasis arising from breast cancer is very poor. Eribulin is a microtubule dynamic inhibitor synthesized from halichondrin B, a natural marine product. In a phase III study (EMBRACE), eribulin improved overall survival in patients with heavily pretreated metastatic breast cancers. However, these studies included few patients with brain metastases. Metastatic brain tumors (MBT) were detected during first-line palliative chemotherapy in a 43-year-old woman with breast cancer metastasis to the lung and mediastinal nodes; the genetic subtype was luminal B-like human epidermal growth factor receptor 2 (HER2)-negative. Whole brain radiotherapy (WBRT) followed by eribulin treatment continuously decreased the size, and induced regression, of the MBT with systemic disease stability for 12 months. Another 48-year-old woman with metastatic breast cancer (HER2+ subtype) presented with MBT. Following surgical resection of the tumor, eribulin with concurrent WBRT showed regression of the MBT without systemic progression for 18 months.-
dc.description.statementOfResponsibilityopen-
dc.languageKorean, English-
dc.publisherKorean Breast Cancer Society-
dc.relation.isPartOfJOURNAL OF BREAST CANCER-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleEribulin Mesylate Combined with Local Treatment for Brain Metastasis from Breast Cancer: Two Case Reports-
dc.typeArticle-
dc.publisher.locationKorea (South)-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Surgery-
dc.contributor.googleauthorKyung-Do Byun-
dc.contributor.googleauthorSung Gwe Ahn-
dc.contributor.googleauthorHyung Joo Baik-
dc.contributor.googleauthorAnbok Lee-
dc.contributor.googleauthorKi Beom Bae-
dc.contributor.googleauthorMin Sung An-
dc.contributor.googleauthorKwang Hee Kim-
dc.contributor.googleauthorJae Ho Shin-
dc.contributor.googleauthorHa Kyoung Park-
dc.contributor.googleauthorHeunglae Cho-
dc.contributor.googleauthorJoon Jeong-
dc.contributor.googleauthorTae Hyun Kim-
dc.identifier.doi10.4048/jbc.2016.19.2.214-
dc.contributor.localIdA03727-
dc.contributor.localIdA02231-
dc.relation.journalcodeJ01279-
dc.identifier.eissn2092-9900-
dc.relation.journalsince2005~-
dc.identifier.pmid27382400-
dc.relation.journalbefore~2004 Journal of Korean Breast Cancer Society (한국유방암학회지)-
dc.subject.keywordBrain-
dc.subject.keywordBreast neoplasms-
dc.subject.keywordEribulin-
dc.subject.keywordNeoplasm metastasis-
dc.contributor.alternativeNameAhn, Sung Gwe-
dc.contributor.alternativeNameJeong, Joon-
dc.contributor.affiliatedAuthorJeong, Joon-
dc.contributor.affiliatedAuthorAhn, Sung Gwe-
dc.citation.volume19-
dc.citation.number2-
dc.citation.startPage214-
dc.citation.endPage217-
dc.identifier.bibliographicCitationJOURNAL OF BREAST CANCER, Vol.19(2) : 214-217, 2016-
dc.date.modified2017-10-24-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.