0 135

Cited 3 times in

Comparison of calcium alginate and carboxymethyl cellulose for nasal packing after endoscopic sinus surgery: a prospective, randomised, controlled single-blinded trial

 D.-Y. Park  ;  H.J. Chung  ;  N.S. Sim  ;  K.H. Jo  ;  D.H. Kim  ;  C.-H. Kim  ;  J.-H. Yoon 
 CLINICAL OTOLARYNGOLOGY, Vol.41(3) : 234-240, 2016 
Journal Title
Issue Date
Adult ; Aged ; Alginates/pharmacology* ; Carboxymethylcellulose Sodium/pharmacology* ; Endoscopy* ; Female ; Glucuronic Acid/pharmacology ; Hexuronic Acids/pharmacology ; Humans ; Male ; Middle Aged ; Pain Measurement ; Prospective Studies ; Rhinitis/surgery* ; Single-Blind Method ; Sinusitis/surgery* ; Tampons, Surgical* ; Treatment Outcome
OBJECTIVES: Calcium alginate is a biodegradable gel-transforming agent widely used for nasal packing. It can reduce pain and improve comfort. However, few randomised controlled trials have compared the efficacy of calcium alginate nasal packing with that of other biodegradable gel-transforming materials. DESIGN: Prospective, randomised, single-blinded controlled study. SETTING: Yonsei University Severance Hospital, a tertiary academic medical centre. PARTICIPANTS: Twenty-seven patients (54 nostrils) with chronic rhinosinusitis who were scheduled for bilateral endoscopic sinus surgery were enrolled. After surgery, one nostril was packed with calcium alginate and the other with carboxymethyl cellulose. Only patients with an intersinus chronic rhinosinusitis severity score difference of ≤1 were included. MAIN OUTCOME MEASURES: Visual analogue scale (VAS) scores for postoperative pain, discomfort from nasal discharge and pain during packing removal were analysed. Two independent rhinologists who were blinded to the assessments separately scored adhesions, oedema and infection by endoscopic digital photography at 1, 4 and 8 weeks postoperatively. RESULTS: There were no significant differences in VAS scores for postoperative pain, discomfort from nasal discharge or pain during packing removal between calcium alginate packings and carboxymethyl cellulose packings. Inter-rater variability of adhesion, oedema and infection scores was acceptable. Adhesion severity and oedema scores at 4 weeks were significantly lower with calcium alginate packing than with carboxymethyl cellulose. Infection severity scores also tended to be lower with calcium alginate than with carboxymethyl cellulose, but the difference was not significant. CONCLUSIONS: Calcium alginate nasal packing is associated with reduced severity of oedema and adhesions after endoscopic sinus surgery.
Full Text
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Otorhinolaryngology (이비인후과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Da Hee(김다희) ORCID logo https://orcid.org/0000-0001-7286-1334
Kim, Chang Hoon(김창훈) ORCID logo https://orcid.org/0000-0003-1238-6396
Yoon, Joo Heon(윤주헌)
사서에게 알리기


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.