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Predictors and Clinical Impacts of Aggravated Left Ventricular Diastolic Dysfunction After Off-Pump Coronary Artery Bypass Grafting

DC FieldValueLanguage
dc.contributor.author유경종-
dc.contributor.author윤영남-
dc.contributor.author이승현-
dc.contributor.author주현철-
dc.date.accessioned2017-10-26T07:26:00Z-
dc.date.available2017-10-26T07:26:00Z-
dc.date.issued2016-
dc.identifier.issn1346-9843-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/152020-
dc.description.abstractBACKGROUND: To determine the predictors of aggravated left ventricular diastolic dysfunction (LVDD) in patients undergoing off-pump coronary artery bypass grafting (OPCAB) and to compare late outcomes according to the aggravated LVDD. METHODS?AND?RESULTS: OPCAB was performed in 1,101 patients (2001-2013). LVDD was classified as normal, mild, moderate or severe. Patients were divided into 2 groups: non-aggravated LVDD (group I) and aggravated LVDD (group II). The primary endpoint was aggravation of LVDD. The secondary endpoint was late mortality and morbidity such as major adverse cardiac and cerebrovascular events (MACCE) related to LVDD aggravation postoperatively. There were 894 patients in group I and 207 in group II. Multivariate analysis revealed that preoperative peripheral artery obstructive disease (PAOD) (P=0.04), renal failure (P<0.01), and A' velocity (P<0.01) anticipated aggravated LVDD. The Cox hazards model revealed that aggravated LVDD was a poor prognostic factor for MACCE (P<0.01) and overall survival (P<0.01). The Kaplan-Meier survival curve showed that aggravated LVDD was related to poor late outcomes (freedom from MACCE, P=0.01; overall survival, P<0.01). CONCLUSIONS: Aggravated LVDD significantly affects late clinical outcomes after OPCAB and preoperative PAOD, renal failure, and A' velocity might be predictors.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish, Japanese-
dc.publisherJapanese Circulation Society-
dc.relation.isPartOfCirculation Journal-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAged-
dc.subject.MESHCoronary Artery Bypass, Off-Pump/adverse effects*-
dc.subject.MESHDisease-Free Survival-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHSurvival Rate-
dc.subject.MESHVentricular Dysfunction, Left*/etiology-
dc.subject.MESHVentricular Dysfunction, Left*/mortality-
dc.subject.MESHVentricular Dysfunction, Left*/physiopathology-
dc.titlePredictors and Clinical Impacts of Aggravated Left Ventricular Diastolic Dysfunction After Off-Pump Coronary Artery Bypass Grafting-
dc.typeArticle-
dc.publisher.locationJapan-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Thoracic & Cardiovascular Surgery-
dc.contributor.googleauthorSeung Hyun Lee-
dc.contributor.googleauthorKwan Wook Kim-
dc.contributor.googleauthorHyun-Chel Joo-
dc.contributor.googleauthorKyung-Jong Yoo-
dc.contributor.googleauthorYoung-Nam Youn-
dc.identifier.doi10.1253/circj.CJ-16-0165-
dc.contributor.localIdA02576-
dc.contributor.localIdA02935-
dc.contributor.localIdA03960-
dc.contributor.localIdA02453-
dc.relation.journalcodeJ00534-
dc.identifier.pmid27477845-
dc.subject.keywordDiastolic heart failure-
dc.subject.keywordDoppler echocardiography-
dc.subject.keywordOff-pump coronary artery bypass-
dc.subject.keywordPeripheral arterial disease-
dc.subject.keywordRenal insufficiency-
dc.contributor.alternativeNameYoo, Kyung Jong-
dc.contributor.alternativeNameYoun, Young Nam-
dc.contributor.alternativeNameLee, Seung Hyun-
dc.contributor.alternativeNameJoo, Hyun Chel-
dc.contributor.affiliatedAuthorYoun, Young Nam-
dc.contributor.affiliatedAuthorLee, Seung Hyun-
dc.contributor.affiliatedAuthorJoo, Hyun Chel-
dc.contributor.affiliatedAuthorYoo, Kyung Jong-
dc.citation.volume80-
dc.citation.number9-
dc.citation.startPage1937-
dc.citation.endPage1945-
dc.identifier.bibliographicCitationCirculation Journal, Vol.80(9) : 1937-1945, 2016-
dc.date.modified2017-10-24-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Thoracic and Cardiovascular Surgery (흉부외과학교실) > 1. Journal Papers

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