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Introduction of the Reliable Estimation of Atopic Dermatitis in ChildHood: Novel, Diagnostic Criteria for Childhood Atopic Dermatitis

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dc.contributor.author박창욱-
dc.contributor.author이광훈-
dc.date.accessioned2017-10-26T07:22:56Z-
dc.date.available2017-10-26T07:22:56Z-
dc.date.issued2016-
dc.identifier.issn2092-7355-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/151953-
dc.description.abstractPURPOSE: Questionnaire-based diagnostic criteria for atopic dermatitis (AD) have been proposed to detect the major group of AD with flexural dermatitis. We aimed to develop novel, questionnaire-based diagnostic criteria for childhood AD, which can detect more comprehensive AD including non-flexural type. METHODS: The draft version of questionnaire to detect childhood AD was prepared to be used for preliminary hospital- (n=1,756) and community-based (n=1,320) surveys. From analysis, the Reliable Estimation of Atopic dermatitis of ChildHood (REACH) was derived and verified in derivation (n=1,129) and validation (n=1,191) sets by community-based surveys. RESULTS: The REACH consists of 11 questions including 2 major and 9 minor criteria. AD is diagnosed as the major group of 'eczema on the antecubital or popliteal fossa' to fulfill the 2 major criteria (2M), and the minor group of 'eczema on the non-antecubital or popliteal fossa' to fulfill the 1 major plus 4 or more minor criteria (1M+4m). In the validation set, the overall 1-year AD prevalence by the REACH was estimated as 12.3% (95% CI, 10.5%-14.2%), and the REACH showed a sensitivity of 75.2%, a specificity of 96.1%, and an error rate of 6.4%. The REACH demonstrated better diagnostic performance than the ISAAC in terms of the number of misclassification (10.0%). CONCLUSIONS: We propose the REACH as new full, questionnaire-based diagnostic criteria for childhood AD in epidemiological surveys. Further studies are warranted to validate the REACH in different populations or countries in the context of large-scale, epidemiological surveys.-
dc.description.statementOfResponsibilityopen-
dc.publisherKorean Academy of Pediatric Allergy and Respiratory Disease-
dc.relation.isPartOfALLERGY ASTHMA & IMMUNOLOGY RESEARCH-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleIntroduction of the Reliable Estimation of Atopic Dermatitis in ChildHood: Novel, Diagnostic Criteria for Childhood Atopic Dermatitis-
dc.typeArticle-
dc.publisher.locationKorea-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Dermatology-
dc.contributor.googleauthorSeung-Chul Lee-
dc.contributor.googleauthorJung Min Bae-
dc.contributor.googleauthorHo-June Lee-
dc.contributor.googleauthorHyun Jung Kim-
dc.contributor.googleauthorByung-Soo Kim-
dc.contributor.googleauthorKapsok Li-
dc.contributor.googleauthorJae-We Cho-
dc.contributor.googleauthorChang Ook Park-
dc.contributor.googleauthorSang Hyun Cho-
dc.contributor.googleauthorKwang Hoon Lee-
dc.contributor.googleauthorDo-Won Kim-
dc.contributor.googleauthorChun Wook Park-
dc.contributor.googleauthorKyu Han Kim-
dc.identifier.doi10.4168/aair.2016.8.3.230-
dc.contributor.localIdA02674-
dc.contributor.localIdA01716-
dc.relation.journalcodeJ00064-
dc.identifier.eissn2092-7363-
dc.identifier.pmid26922933-
dc.subject.keywordAtopic dermatitis-
dc.subject.keywordREACH-
dc.subject.keyworddiagnostic criteria-
dc.subject.keywordquestionnnaire-
dc.contributor.alternativeNamePark, Chang Ook-
dc.contributor.alternativeNameLee, Kwang Hoon-
dc.contributor.affiliatedAuthorLee, Kwang Hoon-
dc.contributor.affiliatedAuthorPark, Chang Ook-
dc.citation.volume8-
dc.citation.number3-
dc.citation.startPage230-
dc.citation.endPage238-
dc.identifier.bibliographicCitationALLERGY ASTHMA & IMMUNOLOGY RESEARCH, Vol.8(3) : 230-238, 2016-
dc.date.modified2017-10-24-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Dermatology (피부과학교실) > 1. Journal Papers

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