61 206

Cited 0 times in

단일기관에서의 단순헤르페스바이러스 2형 수막염의임상특성

DC FieldValueLanguage
dc.contributor.author김원주-
dc.contributor.author라윤경-
dc.contributor.author한철수-
dc.contributor.author황희원-
dc.date.accessioned2017-10-26T07:22:53Z-
dc.date.available2017-10-26T07:22:53Z-
dc.date.issued2016-
dc.identifier.issn1738-1428-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/151952-
dc.description.abstractBackground : Herpes simplex virus type 2 (HSV-2) is the second most common cause of viral meningitis and the most common cause of recurrent meningitis. Although the incidence of HSV-2 meningitis is high, its clinical characteristics are not well known. The purpose of this study was to review the clinical characteristics and prognosis of HSV-2 meningitis. Methods : We analyzed patients who were admitted to the Department of Neurology at Severance Hospital with a final diagnosis of HSV-2 meningitis, as confirmed by applying the polymerase chain reaction to the cerebrospinal fluid (CSF) of patients. Results : The study involved 998 patients with aseptic meningitis and 60 patients diagnosed with HSV-2 meningitis. The mean age at meningitis presentation was 32.5 years (range 18-54 years), and 72% of the patients were female. Common clinical symptoms were headache (100%), nausea and/or vomiting (83%), meningismus (57%), and fever (55%). Six patients had a history of genital herpes infection, and 11 had a past history of recurrent meningitis. The CSF study was notable for elevated protein (111.0±53.5 mg/dL, mean±standard deviation) and white cell count (332.0±211.3 cells/μL). The CSF/serum glucose ratio was 0.52±0.90. Various treatments were applied, including conservative care, antiviral agents, empirical antibiotics, and combined treatments. All patients recovered without serious neurologic sequelae. Conclusions : HSV-2 meningitis is relatively common, as are recurrent episodes. The clinical characteristics of HSV-2 meningitis are similar to those of other types of aseptic meningitis. HSV-2 meningitis is treated using antiviral therapy, and the prognosis is favorable even with conservative treatment.-
dc.description.statementOfResponsibilityopen-
dc.languageKorean-
dc.publisherKorean Neurological Association-
dc.relation.isPartOfJournal of the Korean Neurological Association-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.title단일기관에서의 단순헤르페스바이러스 2형 수막염의임상특성-
dc.title.alternativeClinical Characteristics in Herpes Simplex Virus 2 Meningitis in a Retrospective Single Center Study-
dc.typeArticle-
dc.publisher.locationKorea-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Neurology-
dc.contributor.googleauthor한철수-
dc.contributor.googleauthor김한결-
dc.contributor.googleauthor라윤경-
dc.contributor.googleauthor황희원-
dc.contributor.googleauthor김원주-
dc.identifier.doi10.17340/jkna.2016.2.4-
dc.contributor.localIdA04928-
dc.contributor.localIdA04813-
dc.contributor.localIdA05077-
dc.contributor.localIdA00771-
dc.relation.journalcodeJ01835-
dc.relation.journalsince2004~-
dc.relation.journalbefore~2003 Journal of the Korean Neurological Association (대한신경과학회지)-
dc.contributor.alternativeNameKim, Won Joo-
dc.contributor.alternativeNameLa, Yun Kyung-
dc.contributor.alternativeNameHan, Cheol Soo-
dc.contributor.alternativeNameHwang, Hee Won-
dc.contributor.affiliatedAuthorLa, Yun Kyung-
dc.contributor.affiliatedAuthorHan, Cheol Soo-
dc.contributor.affiliatedAuthorHwang, Hee Won-
dc.contributor.affiliatedAuthorKim, Won Joo-
dc.citation.volume34-
dc.citation.number2-
dc.citation.startPage112-
dc.citation.endPage115-
dc.identifier.bibliographicCitationJournal of the Korean Neurological Association, Vol.34(2) : 112-115, 2016-
dc.date.modified2017-10-24-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurology (신경과학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.