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단일기관에서의 단순헤르페스바이러스 2형 수막염의임상특성
DC Field | Value | Language |
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dc.contributor.author | 김원주 | - |
dc.contributor.author | 라윤경 | - |
dc.contributor.author | 한철수 | - |
dc.contributor.author | 황희원 | - |
dc.date.accessioned | 2017-10-26T07:22:53Z | - |
dc.date.available | 2017-10-26T07:22:53Z | - |
dc.date.issued | 2016 | - |
dc.identifier.issn | 1738-1428 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/151952 | - |
dc.description.abstract | Background : Herpes simplex virus type 2 (HSV-2) is the second most common cause of viral meningitis and the most common cause of recurrent meningitis. Although the incidence of HSV-2 meningitis is high, its clinical characteristics are not well known. The purpose of this study was to review the clinical characteristics and prognosis of HSV-2 meningitis. Methods : We analyzed patients who were admitted to the Department of Neurology at Severance Hospital with a final diagnosis of HSV-2 meningitis, as confirmed by applying the polymerase chain reaction to the cerebrospinal fluid (CSF) of patients. Results : The study involved 998 patients with aseptic meningitis and 60 patients diagnosed with HSV-2 meningitis. The mean age at meningitis presentation was 32.5 years (range 18-54 years), and 72% of the patients were female. Common clinical symptoms were headache (100%), nausea and/or vomiting (83%), meningismus (57%), and fever (55%). Six patients had a history of genital herpes infection, and 11 had a past history of recurrent meningitis. The CSF study was notable for elevated protein (111.0±53.5 mg/dL, mean±standard deviation) and white cell count (332.0±211.3 cells/μL). The CSF/serum glucose ratio was 0.52±0.90. Various treatments were applied, including conservative care, antiviral agents, empirical antibiotics, and combined treatments. All patients recovered without serious neurologic sequelae. Conclusions : HSV-2 meningitis is relatively common, as are recurrent episodes. The clinical characteristics of HSV-2 meningitis are similar to those of other types of aseptic meningitis. HSV-2 meningitis is treated using antiviral therapy, and the prognosis is favorable even with conservative treatment. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | Korean | - |
dc.publisher | Korean Neurological Association | - |
dc.relation.isPartOf | Journal of the Korean Neurological Association | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | 단일기관에서의 단순헤르페스바이러스 2형 수막염의임상특성 | - |
dc.title.alternative | Clinical Characteristics in Herpes Simplex Virus 2 Meningitis in a Retrospective Single Center Study | - |
dc.type | Article | - |
dc.publisher.location | Korea | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Neurology | - |
dc.contributor.googleauthor | 한철수 | - |
dc.contributor.googleauthor | 김한결 | - |
dc.contributor.googleauthor | 라윤경 | - |
dc.contributor.googleauthor | 황희원 | - |
dc.contributor.googleauthor | 김원주 | - |
dc.identifier.doi | 10.17340/jkna.2016.2.4 | - |
dc.contributor.localId | A04928 | - |
dc.contributor.localId | A04813 | - |
dc.contributor.localId | A05077 | - |
dc.contributor.localId | A00771 | - |
dc.relation.journalcode | J01835 | - |
dc.relation.journalsince | 2004~ | - |
dc.relation.journalbefore | ~2003 Journal of the Korean Neurological Association (대한신경과학회지) | - |
dc.contributor.alternativeName | Kim, Won Joo | - |
dc.contributor.alternativeName | La, Yun Kyung | - |
dc.contributor.alternativeName | Han, Cheol Soo | - |
dc.contributor.alternativeName | Hwang, Hee Won | - |
dc.contributor.affiliatedAuthor | La, Yun Kyung | - |
dc.contributor.affiliatedAuthor | Han, Cheol Soo | - |
dc.contributor.affiliatedAuthor | Hwang, Hee Won | - |
dc.contributor.affiliatedAuthor | Kim, Won Joo | - |
dc.citation.volume | 34 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 112 | - |
dc.citation.endPage | 115 | - |
dc.identifier.bibliographicCitation | Journal of the Korean Neurological Association, Vol.34(2) : 112-115, 2016 | - |
dc.date.modified | 2017-10-24 | - |
dc.identifier.rimsid | 46274 | - |
dc.type.rims | ART | - |
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