Cited 10 times in
Association between fractional flow reserve and coronary plaque characteristics assessed by optical coherence tomography
DC Field | Value | Language |
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dc.contributor.author | 고영국 | - |
dc.contributor.author | 홍명기 | - |
dc.contributor.author | 김병극 | - |
dc.contributor.author | 김중선 | - |
dc.contributor.author | 신동호 | - |
dc.contributor.author | 장양수 | - |
dc.contributor.author | 최동훈 | - |
dc.date.accessioned | 2017-10-26T07:19:40Z | - |
dc.date.available | 2017-10-26T07:19:40Z | - |
dc.date.issued | 2016 | - |
dc.identifier.issn | 0914-5087 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/151885 | - |
dc.description.abstract | BACKGROUND: The assessment of fractional flow reserve (FFR) in coronary lesions determines the strategy of percutaneous coronary intervention. However, the association between FFR and characteristics of the underlying coronary plaque has not been sufficiently investigated. METHODS: A total of 110 coronary lesions in 106 patients were evaluated using both FFR and optical coherence tomography (OCT). Coronary plaques were classified into fibrous, fibrocalcific, or fibroatheroma according to OCT evaluation at the site of minimal lumen area. Plaque microstructures such as cap thickness, macrophage accumulation, intimal vasculature, or cholesterol crystals were also evaluated. RESULTS: Lesions with FFR≤0.8 showed a higher frequency of fibroatheroma, macrophage accumulation, and cholesterol crystals when compared to those with FFR>0.8. The angle of lipid was wider in lesions with FFR≤0.8 (145.1±63.0° vs. 120.7±48.9°, p=0.047), and the longitudinal length was longer in those with FFR≤0.8 (4.2±2.8mm vs. 2.5±2.9mm, p=0.007). However, multiple linear regression analysis revealed that the morphological characteristics of plaques assessed by OCT were not independently associated with FFR. Minimal lumen area [coefficient, 0.035; 95% confidence interval (CI), 0.022-0.048; p<0.001] and area stenosis (coefficient, -0.003; 95% CI, -0.005 to -0.001; p=0.001) assessed by OCT significantly correlated with FFR. CONCLUSION: The morphological characteristics of coronary plaque derived from OCT are not directly related to FFR. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | Japanese, English | - |
dc.publisher | Elsevier | - |
dc.relation.isPartOf | JOURNAL OF CARDIOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Coronary Angiography | - |
dc.subject.MESH | Coronary Stenosis/diagnostic imaging* | - |
dc.subject.MESH | Coronary Vessels/diagnostic imaging* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Fractional Flow Reserve, Myocardial* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Plaque, Atherosclerotic/diagnostic imaging* | - |
dc.subject.MESH | Tomography, Optical Coherence* | - |
dc.title | Association between fractional flow reserve and coronary plaque characteristics assessed by optical coherence tomography | - |
dc.type | Article | - |
dc.publisher.location | Netherlands | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Internal Medicine | - |
dc.contributor.googleauthor | Seung-Yul Lee | - |
dc.contributor.googleauthor | Dong-Ho Shin | - |
dc.contributor.googleauthor | Islam Shehata | - |
dc.contributor.googleauthor | Jung-Sun Kim | - |
dc.contributor.googleauthor | Byeong-Keuk Kim | - |
dc.contributor.googleauthor | Young-Guk Ko | - |
dc.contributor.googleauthor | Donghoon Choi | - |
dc.contributor.googleauthor | Yangsoo Jang | - |
dc.contributor.googleauthor | Myeong-Ki Hong | - |
dc.identifier.doi | 10.1016/j.jjcc.2015.10.012 | - |
dc.contributor.localId | A04391 | - |
dc.contributor.localId | A00493 | - |
dc.contributor.localId | A00961 | - |
dc.contributor.localId | A02097 | - |
dc.contributor.localId | A03448 | - |
dc.contributor.localId | A04053 | - |
dc.contributor.localId | A00127 | - |
dc.relation.journalcode | J01287 | - |
dc.identifier.eissn | 1876-4738 | - |
dc.identifier.pmid | 26603326 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S091450871500338X?via%3Dihub | - |
dc.subject.keyword | Coronary disease | - |
dc.subject.keyword | Fractional flow reserve | - |
dc.subject.keyword | Optical coherence tomography | - |
dc.contributor.alternativeName | Ko, Young Guk | - |
dc.contributor.alternativeName | Hong, Myeong Ki | - |
dc.contributor.alternativeName | Kim, Byeong Keuk | - |
dc.contributor.alternativeName | Kim, Jung Sun | - |
dc.contributor.alternativeName | Shin, Dong Ho | - |
dc.contributor.alternativeName | Jang, Yang Soo | - |
dc.contributor.alternativeName | Choi, Dong Hoon | - |
dc.contributor.affiliatedAuthor | Hong, Myeong Ki | - |
dc.contributor.affiliatedAuthor | Kim, Byeong Keuk | - |
dc.contributor.affiliatedAuthor | Kim, Jung Sun | - |
dc.contributor.affiliatedAuthor | Shin, Dong Ho | - |
dc.contributor.affiliatedAuthor | Jang, Yang Soo | - |
dc.contributor.affiliatedAuthor | Choi, Dong Hoon | - |
dc.contributor.affiliatedAuthor | Ko, Young Guk | - |
dc.citation.volume | 68 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 342 | - |
dc.citation.endPage | 345 | - |
dc.identifier.bibliographicCitation | JOURNAL OF CARDIOLOGY, Vol.68(4) : 342-345, 2016 | - |
dc.date.modified | 2017-10-24 | - |
dc.identifier.rimsid | 46210 | - |
dc.type.rims | ART | - |
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