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Early Weight Gain After Transplantation Can Cause Adverse Effect on Transplant Kidney Function

Authors
 I.K. Kim  ;  S.H. Choi  ;  S. Son  ;  M.K. Ju 
Citation
 Transplantation Proceedings, Vol.48(3) : 893-896, 2016 
Journal Title
 Transplantation Proceedings 
ISSN
 0041-1345 
Issue Date
2016
MeSH
Adolescent ; Adult ; Aged ; Female ; Follow-Up Studies ; Glomerular Filtration Rate/physiology* ; Humans ; Kidney/physiopathology* ; Kidney Failure, Chronic/surgery* ; Kidney Transplantation/adverse effects ; Male ; Middle Aged ; Postoperative Complications* ; Retrospective Studies ; Time Factors ; Weight Gain/physiology* ; Young Adult
Abstract
BACKGROUND: The outcomes of kidney transplant recipients with increased body mass index (BMI) remain controversial. We studied the relationship between changes in BMI and kidney transplant function, especially during the first year after transplantation. METHODS: We performed an observational cohort study of all kidney transplant recipients at our center from March 2009 to June 2014 to determine whether changes in BMI were associated with kidney transplant function, as measured by estimated glomerular filtration rate (eGFR). Recipient BMI and eGFR were calculated pre-transplant and at 1, 3, 6, 9, and 12 postoperative months (POM) after transplantation. The correlation between changes in BMI and eGFR was then evaluated. RESULTS: Eighty-one patients were studied. There was a strong negative correlation between changes in BMI and eGFR from pre-transplant to POM 1 (correlation coefficient, -0.406; P < .0001) and from POM 1 to POM 3 (r = -0.324, P = .004). CONCLUSIONS: We found that increased BMI caused a significant decline in renal function as measured by eGFR, especially in the initial 3 months after kidney transplantation.
Full Text
http://www.sciencedirect.com/science/article/pii/S0041134516001044
DOI
10.1016/j.transproceed.2015.10.064
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Im Kyung(김임경) ORCID logo https://orcid.org/0000-0001-8505-5307
Sohn, Sung Yun(손선영)
Joo, Man Ki(주만기) ORCID logo https://orcid.org/0000-0002-4112-7003
Choi, S.H.(최선형)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/151711
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