유전체 의학 시대를 맞이한 유전성 유방암-난소암 증후군 유전 검사의 임상적 함의: 임상의사가 바라본 전망

Other Titles: Clinical Implications of Genetic Testing for Hereditary Breast and Ovarian Cancer Syndrome in the Era of Genomic Medicine: Clinician’s Perspectives

Abstract: Hereditary breast and ovarian cancer syndrome accounts for approximately 5% to 10% of breast or ovarian cancers, with which the highpenetrant
BRCA1/2 genes have been associated. With the recent development of next-generation sequencing (NGS), germline mutation
testing and its related medical and surgical management have been rapidly changing. In this review, we summarize the current status and
perspectives of NGS testing for not only BRCA1/2 but also the other breast and ovarian cancer susceptibility genes

Appears in Collections:: 1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Obstetrics and Gynecology (산부인과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers

Yonsei Authors: Kim, Tae Il(김태일) https://orcid.org/0000-0003-4807-890X
Nam, Eun Ji(남은지) https://orcid.org/0000-0003-0189-3560
Park, Ji Soo(박지수) https://orcid.org/0000-0002-0023-7740
Park, Hyung Seok(박형석) https://orcid.org/0000-0001-5322-6036
Lee, Seung-Tae(이승태) https://orcid.org/0000-0003-1047-1415
Han, Jung Woo(한정우) https://orcid.org/0000-0001-8936-1205

YUHSpace: 유전체 의학 시대를 맞이한 유전성 유방암-난소암 증후군 유전 검사의 임상적 함의: 임상의사가 바라본 전망