Cited 11 times in
Effects of intraoperative inhaled iloprost on primary graft dysfunction after lung transplantation: A retrospective single center study
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김남오 | - |
dc.contributor.author | 오영준 | - |
dc.contributor.author | 유영철 | - |
dc.contributor.author | 이수현 | - |
dc.contributor.author | 이진구 | - |
dc.contributor.author | 이창영 | - |
dc.contributor.author | 김현주 | - |
dc.contributor.author | 백효채 | - |
dc.date.accessioned | 2017-10-26T07:08:03Z | - |
dc.date.available | 2017-10-26T07:08:03Z | - |
dc.date.issued | 2016 | - |
dc.identifier.issn | 0025-7974 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/151646 | - |
dc.description.abstract | DESIGN: Inhaled iloprost was known to alleviate ischemic-reperfusion lung injury. We investigated whether intraoperative inhaled iloprost can prevent the development of primary graft dysfunction after lung transplantation. Data for a consecutive series of patients who underwent lung transplantation with extracorporeal membrane oxygenation were retrieved. By propensity score matching, 2 comparable groups of 30 patients were obtained: patients who inhaled iloprost immediately after reperfusion of the grafted lung (ILO group); patients who did not receive iloprost (non-ILO group). RESULTS: The severity of pulmonary infiltration on postoperative days (PODs) 1 to 3 was significantly lower in the ILO group compared to the non-ILO group. The PaO2/FiO2 ratio was significantly higher in the ILO group compared to the non-ILO group (318.2 ± 74.2 vs 275.9 ± 65.3?mm Hg, P = 0.022 on POD 1; 351.4 ± 58.2 vs 295.8 ± 53.7?mm Hg, P = 0.017 on POD 2; and 378.8 ± 51.9 vs 320.2 ± 66.2?mm Hg, P = 0.013 on POD 3, respectively). The prevalence of the primary graft dysfunction grade 3 was lower in the ILO group compared to the non-ILO group (P = 0.042 on POD 1; P = 0.026 on POD 2; P = 0.024 on POD 3, respectively). The duration of ventilator use and intensive care unit were significantly reduced in the ILO group (P = 0.041 and 0.038). CONCLUSIONS: Intraoperative inhaled iloprost could prevent primary graft dysfunction and preserve allograft function, thus reducing the length of ventilator care and intensive care unit stay, and improving the overall early post-transplant morbidity in patients undergoing lung transplantation. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | English | - |
dc.publisher | Lippincott Williams & Wilkins | - |
dc.relation.isPartOf | MEDICINE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Administration, Inhalation | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Iloprost/administration & dosage* | - |
dc.subject.MESH | Intraoperative Care* | - |
dc.subject.MESH | Lung Transplantation* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Primary Graft Dysfunction/prevention & control* | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Vasodilator Agents/administration & dosage* | - |
dc.title | Effects of intraoperative inhaled iloprost on primary graft dysfunction after lung transplantation: A retrospective single center study | - |
dc.type | Article | - |
dc.publisher.location | United States | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Anesthesiology and Pain Medicine | - |
dc.contributor.googleauthor | Su Hyun Lee | - |
dc.contributor.googleauthor | Jin Gu Lee | - |
dc.contributor.googleauthor | Chang Yeong Lee | - |
dc.contributor.googleauthor | Namo Kim | - |
dc.contributor.googleauthor | Min-Yung Chang | - |
dc.contributor.googleauthor | Young-Chul You | - |
dc.contributor.googleauthor | Hyun Joo Kim | - |
dc.contributor.googleauthor | Hyo Chae Paik | - |
dc.contributor.googleauthor | Young Jun Oh | - |
dc.identifier.doi | 10.1097/MD.0000000000003975 | - |
dc.contributor.localId | A02389 | - |
dc.contributor.localId | A02484 | - |
dc.contributor.localId | A02897 | - |
dc.contributor.localId | A03225 | - |
dc.contributor.localId | A03245 | - |
dc.contributor.localId | A01135 | - |
dc.contributor.localId | A01846 | - |
dc.contributor.localId | A00356 | - |
dc.relation.journalcode | J02214 | - |
dc.identifier.eissn | 1536-5964 | - |
dc.identifier.pmid | 27399072 | - |
dc.subject.keyword | iloprost | - |
dc.subject.keyword | lung transplantation | - |
dc.subject.keyword | primary graft dysfunction | - |
dc.contributor.alternativeName | Kim, Namo | - |
dc.contributor.alternativeName | Oh, Young Jun | - |
dc.contributor.alternativeName | Yoo, Young Chul | - |
dc.contributor.alternativeName | Lee, Su Hyun | - |
dc.contributor.alternativeName | Lee, Jin Gu | - |
dc.contributor.alternativeName | Lee, Chang Young | - |
dc.contributor.alternativeName | Kim, Hyun Zu | - |
dc.contributor.alternativeName | Paik, Hyo Chae | - |
dc.contributor.affiliatedAuthor | Oh, Young Jun | - |
dc.contributor.affiliatedAuthor | Yoo, Young Chul | - |
dc.contributor.affiliatedAuthor | Lee, Su Hyun | - |
dc.contributor.affiliatedAuthor | Lee, Jin Gu | - |
dc.contributor.affiliatedAuthor | Lee, Chang Young | - |
dc.contributor.affiliatedAuthor | Kim, Hyun Joo | - |
dc.contributor.affiliatedAuthor | Paik, Hyo Chae | - |
dc.contributor.affiliatedAuthor | Kim, Namo | - |
dc.citation.volume | 95 | - |
dc.citation.number | 27 | - |
dc.citation.startPage | 3975 | - |
dc.identifier.bibliographicCitation | MEDICINE, Vol.95(27) : 3975, 2016 | - |
dc.date.modified | 2017-10-24 | - |
dc.identifier.rimsid | 45660 | - |
dc.type.rims | ART | - |
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