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Ewing sarcoma: a chronicle of molecular pathogenesis

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dc.contributor.author김상겸-
dc.date.accessioned2017-10-26T07:07:38Z-
dc.date.available2017-10-26T07:07:38Z-
dc.date.issued2016-
dc.identifier.issn0046-8177-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/151633-
dc.description.abstractSarcomas have traditionally been classified according to their chromosomal alterations regardless of whether they accompany simple or complex genetic changes. Ewing sarcoma, a classic small round cell bone tumor, is a well-known mesenchymal malignancy that results from simple sarcoma-specific genetic alterations. The genetic alterations are translocations between genes of the TET/FET family (TLS/FUS, EWSR1, and TAF15) and genes of the E26 transformation-specific (ETS) family. In this review, we intend to summarize a chronicle of molecular findings of Ewing sarcoma including recent advances and explain resultant molecular pathogenesis.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherW B Saunders-
dc.relation.isPartOfHUMAN PATHOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESH12E7 Antigen/analysis-
dc.subject.MESHBiomarkers, Tumor/analysis-
dc.subject.MESHBiomarkers, Tumor/genetics*-
dc.subject.MESHBone Neoplasms/chemistry-
dc.subject.MESHBone Neoplasms/genetics*-
dc.subject.MESHBone Neoplasms/pathology-
dc.subject.MESHChromosome Aberrations-
dc.subject.MESHDiagnosis, Differential-
dc.subject.MESHEpigenesis, Genetic-
dc.subject.MESHGene Expression Regulation, Neoplastic-
dc.subject.MESHGenetic Predisposition to Disease-
dc.subject.MESHHumans-
dc.subject.MESHImmunohistochemistry-
dc.subject.MESHMolecular Diagnostic Techniques-
dc.subject.MESHPhenotype-
dc.subject.MESHPredictive Value of Tests-
dc.subject.MESHPrognosis-
dc.subject.MESHSarcoma, Ewing/chemistry-
dc.subject.MESHSarcoma, Ewing/genetics*-
dc.subject.MESHSarcoma, Ewing/pathology-
dc.subject.MESHTranscription, Genetic-
dc.subject.MESHTranslocation, Genetic-
dc.titleEwing sarcoma: a chronicle of molecular pathogenesis-
dc.typeArticle-
dc.publisher.locationUnited States-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Pathology-
dc.contributor.googleauthorSang Kyum Kim-
dc.contributor.googleauthorYong-Koo Park-
dc.identifier.doi10.1016/j.humpath.2016.05.008-
dc.contributor.localIdA00520-
dc.relation.journalcodeJ01011-
dc.identifier.eissn1532-8392-
dc.identifier.pmid27246176-
dc.identifier.urlhttp://www.sciencedirect.com/science/article/pii/S0046817716300892-
dc.subject.keywordChromosomal translocation-
dc.subject.keywordEwing sarcoma-
dc.subject.keywordMolecular pathogenesis-
dc.contributor.alternativeNameKim, Sang Kyum-
dc.contributor.affiliatedAuthorKim, Sang Kyum-
dc.citation.volume55-
dc.citation.startPage91-
dc.citation.endPage100-
dc.identifier.bibliographicCitationHUMAN PATHOLOGY, Vol.55 : 91-100, 2016-
dc.date.modified2017-10-24-
dc.identifier.rimsid45269-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
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