287 309

Cited 0 times in

자궁내막증 여성 난소 조직의 태아 기원 microchimerism에 관한 연구

Other Titles
 Microchimerism of Fetal Origin in Ovarian Tissues from Women with Pelvic Endometriosis 
Authors
 장진범  ;  이숙환  ;  이병석  ;  김종욱  ;  박상원  ;  이정노  ;  문영기  ;  윤태기  ;  차동현 
Citation
 Korean Journal of Obstetrics and Gynecology (대한산부인과학회지), Vol.48(6) : 1506-1512, 2005 
Journal Title
Korean Journal of Obstetrics and Gynecology(대한산부인과학회지)
ISSN
 1738-5628 
Issue Date
2005
MeSH
Microchimerism ; Endometriosis
Keywords
Microchimerism ; Endometriosis
Abstract
Objective: To investigate whether fetal microchimeric cells were detected in ovarian tissues with pelvic endometriosis.

Methods: Ovarian tissues with endometriosis were obtained from five women who had at least one live-born son and who underwent enucleation of endometriotic cyst or oophorectomy after a diagnosis of endometriotic cyst. Control tissues were obtained from five women with endometriosis who had no pregnant history. Tissue sections were analyzed with fluorescence in situ hybridization for the presence of fetal cells, defined by X and Y chromosome.

Results: Fluorescence in situ hybridization using paraffin-embedded ovarian specimens was performed successfully. Male cells were found in ovarian tissues from all five patients. No male cells were found in ovarian tissues from all five controls.

Conclusion: Fetal microchimeric cells, possibly from feto-maternal cell trafficking were detected in ovarian tissues with endometriosis were obtained from women who had prior male pregnancies. Further study is necessary to understand the role of persistent fetal microchimeric cells in the progression of endometriosis.
Files in This Item:
T200501339.pdf Download
DOI
OAK-2005-06011
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Obstetrics and Gynecology (산부인과학교실) > 1. Journal Papers
Yonsei Authors
Lee, Byung Seok(이병석) ORCID logo https://orcid.org/0000-0001-6001-2079
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/151440
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse

Links