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스텐트재협착환자에서 커팅벌룬성형술후 166Ho-DTPA 액체풍선도자를 이용한 방사선근접조사법의 치료효과(BRAHMS 연구)
DC Field | Value | Language |
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dc.contributor.author | 고영국 | - |
dc.contributor.author | 최동훈 | - |
dc.date.accessioned | 2017-10-26T06:50:34Z | - |
dc.date.available | 2017-10-26T06:50:34Z | - |
dc.date.issued | 2005 | - |
dc.identifier.issn | 1738-5520 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/151386 | - |
dc.description.abstract | Background and Objectives:Vascular brachytherapy for stent restenosis has been demonstrated to reduce restenosis and major adverse cardiac events (MACE). However, the angiographic and clinical outcomes after β-radiation, using a 166Holmium (Ho)-DTPA filled balloon, has not been sufficiently evaluated. Subjects and Methods:Between March 2002 and August 2003, 78 consecutive patients (mean age 50 yrs, 53 male) with in-stent restenosis were randomly enrolled for either cutting balloon angioplasty only (control group, n=38) or in combination with vascular brachytherapy using a 166Ho-DTPA filled balloon (brachytherapy group, n=40). The radiation dose applied was 18 Gy, at a depth of 1.0 mm from the vascular lumen. Results:The treated vessels comprised of 50 left anterior descending arteries (64.1%), 23 right coronary arteries (29.5%) and 5 circumflex arteries. The mean radiation dose and time were 375±67.8 mCi/ml and 191±76 seconds, respectively. Six cases were fractionated.The mean lesion length was 18.2±7.9 mm, with no difference between the 2 groups. Eight month follow-up coronary angiography revealed a restenosis rate of 17.1% (6/35) in the brachytherapy group vs. 39.3% (11/27) in the control group(p=0.042). However, there was no difference in the 1 year MACE. Conclusion:In patients with in-stent restenosis, vascular brachytherapy, using a 166Ho-DTPA filled balloon, showed favorable angiographic outcomes at the 8 month follow-up compared to the control group | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English, Korean | - |
dc.publisher | Korean Society of Circulation | - |
dc.relation.isPartOf | KOREAN CIRCULATION JOURNAL | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Coronary restenosis;Brachytherapy;Angioplasty | - |
dc.title | 스텐트재협착환자에서 커팅벌룬성형술후 166Ho-DTPA 액체풍선도자를 이용한 방사선근접조사법의 치료효과(BRAHMS 연구) | - |
dc.title.alternative | Effect of Vascular BRAchytherapy using HolmiuM-166 Liquid Balloon System afterCutting Balloon Angioplasty in Patients with Stent Restenosis(BRAHMS Study) | - |
dc.type | Article | - |
dc.publisher.location | Korea | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | 김수형 | - |
dc.contributor.googleauthor | 김무현 | - |
dc.contributor.googleauthor | 차광수 | - |
dc.contributor.googleauthor | 최동훈 | - |
dc.contributor.googleauthor | 고영국 | - |
dc.contributor.googleauthor | 권현철 | - |
dc.contributor.googleauthor | 박종선 | - |
dc.contributor.googleauthor | 김영조 | - |
dc.contributor.googleauthor | 정명호 | - |
dc.contributor.googleauthor | 강도영 | - |
dc.contributor.googleauthor | 이형식 | - |
dc.identifier.doi | OAK-2005-05676 | - |
dc.contributor.localId | A00127 | - |
dc.contributor.localId | A04053 | - |
dc.relation.journalcode | J01952 | - |
dc.identifier.eissn | 1738-5555 | - |
dc.relation.journalsince | 2005~ | - |
dc.relation.journalbefore | ~2004 Korean Circulation Journal (순환기) | - |
dc.subject.keyword | Coronary restenosis;Brachytherapy;Angioplasty | - |
dc.contributor.alternativeName | Ko, Young Guk | - |
dc.contributor.alternativeName | Ko, Young Guk | - |
dc.contributor.alternativeName | Choi, Dong Hoon | - |
dc.contributor.affiliatedAuthor | 고영국 | - |
dc.citation.volume | 35 | - |
dc.citation.number | 8 | - |
dc.citation.startPage | 591 | - |
dc.citation.endPage | 596 | - |
dc.identifier.bibliographicCitation | KOREAN CIRCULATION JOURNAL, Vol.35(8) : 591-596, 2005 | - |
dc.date.modified | 2017-05-04 | - |
dc.identifier.rimsid | 44099 | - |
dc.type.rims | ART | - |
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