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A Comparison of Clinical Features and Mortality among Methicillin-Resistant and Methicillin-Sensitive Strains of Staphylococcus aureus Endocarditis

DC FieldValueLanguage
dc.contributor.author김준명-
dc.contributor.author김창오-
dc.contributor.author송영구-
dc.contributor.author윤희정-
dc.contributor.author최준용-
dc.date.accessioned2017-10-26T06:46:24Z-
dc.date.available2017-10-26T06:46:24Z-
dc.date.issued2005-
dc.identifier.issn0513-5796-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/151274-
dc.description.abstractOur objective was to assess the clinical factors that would reliably distinguish methicillin-resistant S. aureus (MRSA) from methicillin-susceptible S. aureus (MSSA) endocarditis. A retrospective cohort study of clinical features and mortality in patients with MRSA and MSSA endocarditis between March 1986 and March 2004 was performed in a 750-bed, tertiary care teaching hospital. A total of 32 patients (10 MRSA [31.3%] vs 22 MSSA [68.7%]) were evaluated. Their mean age and sex ratio (male/female) were as follows: 30.8 ± 16.0 vs 24.4±19.6 years old and 6/4 vs 13/9, for MRSA and MSSA infective endocarditis (IE), respectively. Univariate and multivariate analyses revealed that persistent bacteremia was significantly more prevalent in MRSA IE (OR, 10.0 [1.480-67.552]; p, 0.018). There was a higher mortality trend for MRSA IE (50.0%) than for MSSA IE (9.1%) (p=0.019). However, persistent bacteremia was not associated with higher mortality (p>0.05). These results indicate that if persistent bacteremia is documented, the likelihood of MRSA endocarditis should be viewed as high, and the patient's antistaphylococcal therapy should be prolonged and/or changed to a more "potent" regimen.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherYonsei University-
dc.relation.isPartOfYONSEI MEDICAL JOURNAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHBacteremia/drug therapy-
dc.subject.MESHBacteremia/microbiology-
dc.subject.MESHCohort Studies-
dc.subject.MESHEndocarditis, Bacterial/drug therapy-
dc.subject.MESHEndocarditis, Bacterial/microbiology*-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMethicillin Resistance*-
dc.subject.MESHMiddle Aged-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHStaphylococcal Infections/drug therapy-
dc.subject.MESHStaphylococcal Infections/microbiology*-
dc.subject.MESHStaphylococcus aureus/drug effects*-
dc.titleA Comparison of Clinical Features and Mortality among Methicillin-Resistant and Methicillin-Sensitive Strains of Staphylococcus aureus Endocarditis-
dc.typeArticle-
dc.publisher.locationKorea (South)-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.googleauthorHee Jung Yoon-
dc.contributor.googleauthorJun Yong Choi-
dc.contributor.googleauthorChang Oh Kim-
dc.contributor.googleauthorJune Myung Kim-
dc.contributor.googleauthorYoung Goo Song-
dc.identifier.doi10.3349/ymj.2005.46.4.496-
dc.contributor.localIdA00953-
dc.contributor.localIdA01044-
dc.contributor.localIdA02037-
dc.contributor.localIdA02632-
dc.contributor.localIdA04191-
dc.relation.journalcodeJ02813-
dc.identifier.eissn1976-2437-
dc.identifier.pmid16127774-
dc.subject.keywordStaphylococcus aureus-
dc.subject.keywordbacteremia-
dc.subject.keywordendocarditis-
dc.contributor.alternativeNameKim, June Myung-
dc.contributor.alternativeNameKim, Chang Oh-
dc.contributor.alternativeNameSong, Young Goo-
dc.contributor.alternativeNameYoon, Hee Jung-
dc.contributor.alternativeNameChoi, Jun Yong-
dc.citation.volume46-
dc.citation.number4-
dc.citation.startPage496-
dc.citation.endPage502-
dc.identifier.bibliographicCitationYONSEI MEDICAL JOURNAL, Vol.46(4) : 496-502, 2005-
dc.date.modified2017-05-04-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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