Cited 8 times in
Duodenal Somatostatinoma Associated with Diabetic Ketoacidosis Presumably Caused by Somatostatin-28 Hypersecretion
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김경래 | - |
dc.contributor.author | 김똘미 | - |
dc.contributor.author | 안철우 | - |
dc.contributor.author | 이은직 | - |
dc.contributor.author | 이현철 | - |
dc.contributor.author | 임승길 | - |
dc.contributor.author | 차봉수 | - |
dc.contributor.author | 홍순원 | - |
dc.date.accessioned | 2017-10-26T06:43:09Z | - |
dc.date.available | 2017-10-26T06:43:09Z | - |
dc.date.issued | 2005 | - |
dc.identifier.issn | 0021-972X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/151211 | - |
dc.description.abstract | CONTEXT: Extrapancreatic somatostatinoma is very rare and clinically distinguished from its pancreatic counterpart because somatostatinoma syndrome with mild diabetes is rare in extrapancreatic somatostatinoma because of poor secretion of somatostatin. Moreover, because somatostatin inhibits the secretion of insulin and glucagon simultaneously, true diabetic ketoacidosis (DKA) seldom ensues. PATIENT: A 23-yr-old woman presented with DKA and an abdominal mass. A computed tomography scan showed a huge, encapsulated mass in a duodenal submucous portion. A high circulating level of somatostatin was detected (67.2 pmol/liter; reference range, 0.6-7.3 pmol/liter). INTERVENTION: The tumor mass was successfully removed with Whipple's procedure, and the patient gradually recovered both clinically and biochemically. RESULTS: Immunohistochemical staining of the tumor tissue exhibited diffusely positive for somatostatin and somatostatin-28 but negative for insulin, glucagon, calcitonin, serotonin, and S-100. CONCLUSION: As far as we know, this is the first case report of gastrointestinal somatostatinoma associated with DKA. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Endocrine Society | - |
dc.relation.isPartOf | JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | DNA/analysis | - |
dc.subject.MESH | Diabetic Ketoacidosis/complications* | - |
dc.subject.MESH | Duodenal Neoplasms/etiology* | - |
dc.subject.MESH | Duodenal Neoplasms/metabolism | - |
dc.subject.MESH | Duodenal Neoplasms/pathology | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Immunohistochemistry | - |
dc.subject.MESH | Somatostatin/analysis | - |
dc.subject.MESH | Somatostatin/metabolism* | - |
dc.subject.MESH | Somatostatin-28 | - |
dc.subject.MESH | Somatostatinoma/etiology* | - |
dc.subject.MESH | Somatostatinoma/metabolism | - |
dc.subject.MESH | Somatostatinoma/pathology | - |
dc.title | Duodenal Somatostatinoma Associated with Diabetic Ketoacidosis Presumably Caused by Somatostatin-28 Hypersecretion | - |
dc.type | Article | - |
dc.publisher.location | United States | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.department | Dept. of Pathology (병리학교실) | - |
dc.contributor.googleauthor | Dol Mi Kim | - |
dc.contributor.googleauthor | Chul Woo Ahn | - |
dc.contributor.googleauthor | Kyung Rae Kim | - |
dc.contributor.googleauthor | Soon Won Hong | - |
dc.contributor.googleauthor | Moon Suk Nam | - |
dc.contributor.googleauthor | Bong Soo Cha | - |
dc.contributor.googleauthor | Sung Kil Lim | - |
dc.contributor.googleauthor | Hyun Chul Lee | - |
dc.contributor.googleauthor | Eun Jig Lee | - |
dc.identifier.doi | 10.1210/jc.2004-1904 | - |
dc.contributor.localId | A00294 | - |
dc.contributor.localId | A00418 | - |
dc.contributor.localId | A01248 | - |
dc.contributor.localId | A02270 | - |
dc.contributor.localId | A03050 | - |
dc.contributor.localId | A03301 | - |
dc.contributor.localId | A03375 | - |
dc.contributor.localId | A03996 | - |
dc.contributor.localId | A04411 | - |
dc.relation.journalcode | J01318 | - |
dc.identifier.eissn | 1945-7197 | - |
dc.identifier.pmid | 16105971 | - |
dc.identifier.url | https://academic.oup.com/jcem/article/90/11/6310/2838509 | - |
dc.subject.keyword | 16105971 | - |
dc.contributor.alternativeName | Kim, Kyung Rae | - |
dc.contributor.alternativeName | Kim, Dol Mi | - |
dc.contributor.alternativeName | Nam, Moon Suk | - |
dc.contributor.alternativeName | Ahn, Chul Woo | - |
dc.contributor.alternativeName | Lee, Eun Jig | - |
dc.contributor.alternativeName | Lee, Hyun Chul | - |
dc.contributor.alternativeName | Lim, Sung Kil | - |
dc.contributor.alternativeName | Cha, Bong Soo | - |
dc.contributor.alternativeName | Hong, Soon Won | - |
dc.citation.volume | 90 | - |
dc.citation.number | 11 | - |
dc.citation.startPage | 6310 | - |
dc.citation.endPage | 6315 | - |
dc.identifier.bibliographicCitation | JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, Vol.90(11) : 6310-6315, 2005 | - |
dc.date.modified | 2017-05-04 | - |
dc.identifier.rimsid | 43933 | - |
dc.type.rims | ART | - |
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