Cited 114 times in
Dissemination of SHV-12 and CTX-M-type extended-spectrum β-lactamases among clinical isolates of Escherichia coli and Klebsiella pneumoniae and emergence of GES-3 in Korea
DC Field | Value | Language |
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dc.contributor.author | 배일권 | - |
dc.contributor.author | 이경원 | - |
dc.date.accessioned | 2017-10-26T06:38:14Z | - |
dc.date.available | 2017-10-26T06:38:14Z | - |
dc.date.issued | 2005 | - |
dc.identifier.issn | 0305-7453 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/151110 | - |
dc.description.abstract | OBJECTIVES: To assess the prevalence and genotypes of Ambler class A extended-spectrum beta-lactamases (ESBLs) in Korea. METHODS: Clinical isolates of Escherichia coli and Klebsiella pneumoniae collected from 12 Korean hospitals during February-July 2003 were evaluated. Antimicrobial susceptibilities were determined by disc diffusion and agar dilution methods, and the putative ESBL-producing strains were tested by the double-disc synergy method. Detection of genes encoding class A beta-lactamases was performed by PCR amplification, and the PCR products were subjected to direct sequencing. RESULTS: The double-disc synergy test showed positive results in 9.3% (23/246) of E. coli and 23.0% (55/239) of K. pneumoniae isolates. The most prevalent types of Ambler class A ESBLs in E. coli isolates were CTX-M-15 (n = 4) and CTX-M-3 (n = 3), and those in K. pneumoniae isolates were SHV-12 (n = 30) and CTX-M-3 (n = 13). Two isolates produced both SHV-12 and GES-3, simultaneously. CONCLUSIONS: CTX-M-type and/or SHV-12 ESBL-producing E. coli and K. pneumoniae isolates are spreading, and a GES-type ESBL has emerged in Korea. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Oxford University Press | - |
dc.relation.isPartOf | JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Anti-Bacterial Agents/pharmacology | - |
dc.subject.MESH | Drug Resistance, Bacterial | - |
dc.subject.MESH | Escherichia coli/drug effects | - |
dc.subject.MESH | Escherichia coli/enzymology* | - |
dc.subject.MESH | Escherichia coli/genetics | - |
dc.subject.MESH | Escherichia coli/isolation & purification | - |
dc.subject.MESH | Escherichia coli Infections/epidemiology | - |
dc.subject.MESH | Escherichia coli Infections/microbiology* | - |
dc.subject.MESH | Hospitals | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Klebsiella Infections/epidemiology | - |
dc.subject.MESH | Klebsiella Infections/microbiology* | - |
dc.subject.MESH | Klebsiella pneumoniae/drug effects | - |
dc.subject.MESH | Klebsiella pneumoniae/enzymology* | - |
dc.subject.MESH | Klebsiella pneumoniae/genetics | - |
dc.subject.MESH | Klebsiella pneumoniae/isolation & purification | - |
dc.subject.MESH | Korea/epidemiology | - |
dc.subject.MESH | Microbial Sensitivity Tests | - |
dc.subject.MESH | beta-Lactamases/genetics* | - |
dc.title | Dissemination of SHV-12 and CTX-M-type extended-spectrum β-lactamases among clinical isolates of Escherichia coli and Klebsiella pneumoniae and emergence of GES-3 in Korea | - |
dc.type | Article | - |
dc.publisher.location | England | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Laboratory Medicine (진단검사의학교실) | - |
dc.contributor.department | Dept. of Laboratory Medicine (진단검사의학교실) | - |
dc.contributor.googleauthor | Nam Hee Ryoo | - |
dc.contributor.googleauthor | Eui-Chong Kim | - |
dc.contributor.googleauthor | Seong Geun Hong | - |
dc.contributor.googleauthor | Yeon Joon Park | - |
dc.contributor.googleauthor | Kyungwon Lee | - |
dc.contributor.googleauthor | Il Kwon Bae | - |
dc.contributor.googleauthor | Eun Hyang Song | - |
dc.contributor.googleauthor | Seok Hoon Jeong | - |
dc.identifier.doi | 10.1093/jac/dki324 | - |
dc.contributor.localId | A01802 | - |
dc.contributor.localId | A02649 | - |
dc.relation.journalcode | J01237 | - |
dc.identifier.eissn | 1460-2091 | - |
dc.identifier.pmid | 16141280 | - |
dc.subject.keyword | ESBLs | - |
dc.subject.keyword | resistance | - |
dc.subject.keyword | prevalence | - |
dc.contributor.alternativeName | Bae, Il Kwon | - |
dc.contributor.alternativeName | Lee, Kyung Won | - |
dc.citation.volume | 56 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 698 | - |
dc.citation.endPage | 702 | - |
dc.identifier.bibliographicCitation | JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, Vol.56(4) : 698-702, 2005 | - |
dc.date.modified | 2017-05-04 | - |
dc.identifier.rimsid | 43452 | - |
dc.type.rims | ART | - |
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