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Dissemination of SHV-12 and CTX-M-type extended-spectrum β-lactamases among clinical isolates of Escherichia coli and Klebsiella pneumoniae and emergence of GES-3 in Korea

DC Field Value Language
dc.contributor.author배일권-
dc.contributor.author이경원-
dc.date.accessioned2017-10-26T06:38:14Z-
dc.date.available2017-10-26T06:38:14Z-
dc.date.issued2005-
dc.identifier.issn0305-7453-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/151110-
dc.description.abstractOBJECTIVES: To assess the prevalence and genotypes of Ambler class A extended-spectrum beta-lactamases (ESBLs) in Korea. METHODS: Clinical isolates of Escherichia coli and Klebsiella pneumoniae collected from 12 Korean hospitals during February-July 2003 were evaluated. Antimicrobial susceptibilities were determined by disc diffusion and agar dilution methods, and the putative ESBL-producing strains were tested by the double-disc synergy method. Detection of genes encoding class A beta-lactamases was performed by PCR amplification, and the PCR products were subjected to direct sequencing. RESULTS: The double-disc synergy test showed positive results in 9.3% (23/246) of E. coli and 23.0% (55/239) of K. pneumoniae isolates. The most prevalent types of Ambler class A ESBLs in E. coli isolates were CTX-M-15 (n = 4) and CTX-M-3 (n = 3), and those in K. pneumoniae isolates were SHV-12 (n = 30) and CTX-M-3 (n = 13). Two isolates produced both SHV-12 and GES-3, simultaneously. CONCLUSIONS: CTX-M-type and/or SHV-12 ESBL-producing E. coli and K. pneumoniae isolates are spreading, and a GES-type ESBL has emerged in Korea.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherOxford University Press-
dc.relation.isPartOfJOURNAL OF ANTIMICROBIAL CHEMOTHERAPY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAnti-Bacterial Agents/pharmacology-
dc.subject.MESHDrug Resistance, Bacterial-
dc.subject.MESHEscherichia coli/drug effects-
dc.subject.MESHEscherichia coli/enzymology*-
dc.subject.MESHEscherichia coli/genetics-
dc.subject.MESHEscherichia coli/isolation & purification-
dc.subject.MESHEscherichia coli Infections/epidemiology-
dc.subject.MESHEscherichia coli Infections/microbiology*-
dc.subject.MESHHospitals-
dc.subject.MESHHumans-
dc.subject.MESHKlebsiella Infections/epidemiology-
dc.subject.MESHKlebsiella Infections/microbiology*-
dc.subject.MESHKlebsiella pneumoniae/drug effects-
dc.subject.MESHKlebsiella pneumoniae/enzymology*-
dc.subject.MESHKlebsiella pneumoniae/genetics-
dc.subject.MESHKlebsiella pneumoniae/isolation & purification-
dc.subject.MESHKorea/epidemiology-
dc.subject.MESHMicrobial Sensitivity Tests-
dc.subject.MESHbeta-Lactamases/genetics*-
dc.titleDissemination of SHV-12 and CTX-M-type extended-spectrum β-lactamases among clinical isolates of Escherichia coli and Klebsiella pneumoniae and emergence of GES-3 in Korea-
dc.typeArticle-
dc.publisher.locationEngland-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Laboratory Medicine (진단검사의학교실)-
dc.contributor.departmentDept. of Laboratory Medicine (진단검사의학교실)-
dc.contributor.googleauthorNam Hee Ryoo-
dc.contributor.googleauthorEui-Chong Kim-
dc.contributor.googleauthorSeong Geun Hong-
dc.contributor.googleauthorYeon Joon Park-
dc.contributor.googleauthorKyungwon Lee-
dc.contributor.googleauthorIl Kwon Bae-
dc.contributor.googleauthorEun Hyang Song-
dc.contributor.googleauthorSeok Hoon Jeong-
dc.identifier.doi10.1093/jac/dki324-
dc.contributor.localIdA01802-
dc.contributor.localIdA02649-
dc.relation.journalcodeJ01237-
dc.identifier.eissn1460-2091-
dc.identifier.pmid16141280-
dc.subject.keywordESBLs-
dc.subject.keywordresistance-
dc.subject.keywordprevalence-
dc.contributor.alternativeNameBae, Il Kwon-
dc.contributor.alternativeNameLee, Kyung Won-
dc.citation.volume56-
dc.citation.number4-
dc.citation.startPage698-
dc.citation.endPage702-
dc.identifier.bibliographicCitationJOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, Vol.56(4) : 698-702, 2005-
dc.date.modified2017-05-04-
dc.identifier.rimsid43452-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers

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