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Does a carbon ion-implanted surface reduce the restenosis rate of coronary stents?

DC FieldValueLanguage
dc.contributor.author고영국-
dc.contributor.author김종윤-
dc.contributor.author박성하-
dc.contributor.author심원흠-
dc.contributor.author장양수-
dc.contributor.author조승연-
dc.contributor.author최동훈-
dc.contributor.author최의영-
dc.contributor.author민필기-
dc.date.accessioned2017-10-26T06:36:55Z-
dc.date.available2017-10-26T06:36:55Z-
dc.date.issued2005-
dc.identifier.issn0008-6312-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/151082-
dc.description.abstractBACKGROUND: Neointimal hyperplasia and resulting restenosis limit the long-term success of coronary stenting. Heavy metal ions induce an inflammatory and allergic reaction, and result in in-stent restenosis. However, a carbon ion-implanted surface might prevent heavy metal ions from diffusing into surrounding tissue. METHODS: 140 lesions in 140 patients with coronary lesions underwent implantation of carbon-implanted surface stents (Arthos(inert) stent group, n=70) or control stents (Arthos stent group, n=70). The primary end point was the in-stent restenosis and the secondary end point was the value of hs-CRP at 48 h and 6 months after coronary stenting. Clinical and angiographic follow-ups were performed at 6 months. RESULTS: The rate of in-stent restenosis was lower in the Arthos(inert) stent group (15.9%, 10/63) than in the Arthos stent group (20.9%, 13/62), but there were no significant differences between both groups (p=0.56). The value of hs-CRP at 48 h was lower in the Arthos(inert) stent group (13.9+/-13.4 mg/dl) than in the Arthos stent group (24.5+/-26.0 mg/dl) with significant differences (p=0.04). However, the differences between two groups were not statistically significant at 6 months (p=0.76). CONCLUSIONS: As compared with a standard coronary stent, a carbon ion-implanted stent shows no considerable benefit for the prevention of in-stent restenosis within the range of this study. Despite all the limitations of this study, a positive effect of a carbon ion-implanted stent in reducing inflammatory reaction after coronary revascularization seems likely.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherKarger-
dc.relation.isPartOfCARDIOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHAngioplasty, Balloon, Coronary*-
dc.subject.MESHC-Reactive Protein/metabolism-
dc.subject.MESHCarbon*-
dc.subject.MESHCoronary Restenosis/prevention & control*-
dc.subject.MESHCoronary Stenosis/therapy*-
dc.subject.MESHFemale-
dc.subject.MESHFibromuscular Dysplasia/prevention & control*-
dc.subject.MESHHumans-
dc.subject.MESHIons*-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHProspective Studies-
dc.subject.MESHProsthesis Design-
dc.subject.MESHProsthesis Failure-
dc.subject.MESHStents*-
dc.titleDoes a carbon ion-implanted surface reduce the restenosis rate of coronary stents?-
dc.typeArticle-
dc.publisher.locationSwitzerland-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.googleauthorJung J.-H.-
dc.contributor.googleauthorMin P.-K.-
dc.contributor.googleauthorKim J.-Y.-
dc.contributor.googleauthorPark S.-
dc.contributor.googleauthorChoi E.-Y.-
dc.contributor.googleauthorKo Y.-G.-
dc.contributor.googleauthorChoi D.-
dc.contributor.googleauthorJang Y.-
dc.contributor.googleauthorShim W.-H.-
dc.contributor.googleauthorCho S.-Y.-
dc.identifier.doi10.1159/000086688-
dc.contributor.localIdA00127-
dc.contributor.localIdA00926-
dc.contributor.localIdA01512-
dc.contributor.localIdA02202-
dc.contributor.localIdA03448-
dc.contributor.localIdA03844-
dc.contributor.localIdA04053-
dc.contributor.localIdA04165-
dc.relation.journalcodeJ00457-
dc.identifier.eissn1421-9751-
dc.identifier.pmid16020923-
dc.identifier.urlhttp://www.karger.com/Article/FullText/86688-
dc.subject.keywordRestenosis, coronary-
dc.subject.keywordCarbon-
dc.subject.keywordInflammation-
dc.contributor.alternativeNameKo, Young Guk-
dc.contributor.alternativeNameKim, Jong Youn-
dc.contributor.alternativeNamePark, Sung Ha-
dc.contributor.alternativeNameShim, Won Heum-
dc.contributor.alternativeNameJang, Yang Soo-
dc.contributor.alternativeNameCho, Seung Yun-
dc.contributor.alternativeNameChoi, Dong Hoon-
dc.contributor.alternativeNameChoi, Eui Young-
dc.citation.volume104-
dc.citation.number2-
dc.citation.startPage72-
dc.citation.endPage75-
dc.identifier.bibliographicCitationCARDIOLOGY, Vol.104(2) : 72-75, 2005-
dc.date.modified2017-05-04-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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