Cited 5 times in
Does a carbon ion-implanted surface reduce the restenosis rate of coronary stents?
DC Field | Value | Language |
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dc.contributor.author | 고영국 | - |
dc.contributor.author | 김종윤 | - |
dc.contributor.author | 박성하 | - |
dc.contributor.author | 심원흠 | - |
dc.contributor.author | 장양수 | - |
dc.contributor.author | 조승연 | - |
dc.contributor.author | 최동훈 | - |
dc.contributor.author | 최의영 | - |
dc.contributor.author | 민필기 | - |
dc.date.accessioned | 2017-10-26T06:36:55Z | - |
dc.date.available | 2017-10-26T06:36:55Z | - |
dc.date.issued | 2005 | - |
dc.identifier.issn | 0008-6312 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/151082 | - |
dc.description.abstract | BACKGROUND: Neointimal hyperplasia and resulting restenosis limit the long-term success of coronary stenting. Heavy metal ions induce an inflammatory and allergic reaction, and result in in-stent restenosis. However, a carbon ion-implanted surface might prevent heavy metal ions from diffusing into surrounding tissue. METHODS: 140 lesions in 140 patients with coronary lesions underwent implantation of carbon-implanted surface stents (Arthos(inert) stent group, n=70) or control stents (Arthos stent group, n=70). The primary end point was the in-stent restenosis and the secondary end point was the value of hs-CRP at 48 h and 6 months after coronary stenting. Clinical and angiographic follow-ups were performed at 6 months. RESULTS: The rate of in-stent restenosis was lower in the Arthos(inert) stent group (15.9%, 10/63) than in the Arthos stent group (20.9%, 13/62), but there were no significant differences between both groups (p=0.56). The value of hs-CRP at 48 h was lower in the Arthos(inert) stent group (13.9+/-13.4 mg/dl) than in the Arthos stent group (24.5+/-26.0 mg/dl) with significant differences (p=0.04). However, the differences between two groups were not statistically significant at 6 months (p=0.76). CONCLUSIONS: As compared with a standard coronary stent, a carbon ion-implanted stent shows no considerable benefit for the prevention of in-stent restenosis within the range of this study. Despite all the limitations of this study, a positive effect of a carbon ion-implanted stent in reducing inflammatory reaction after coronary revascularization seems likely. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Karger | - |
dc.relation.isPartOf | CARDIOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Angioplasty, Balloon, Coronary* | - |
dc.subject.MESH | C-Reactive Protein/metabolism | - |
dc.subject.MESH | Carbon* | - |
dc.subject.MESH | Coronary Restenosis/prevention & control* | - |
dc.subject.MESH | Coronary Stenosis/therapy* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Fibromuscular Dysplasia/prevention & control* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Ions* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Prospective Studies | - |
dc.subject.MESH | Prosthesis Design | - |
dc.subject.MESH | Prosthesis Failure | - |
dc.subject.MESH | Stents* | - |
dc.title | Does a carbon ion-implanted surface reduce the restenosis rate of coronary stents? | - |
dc.type | Article | - |
dc.publisher.location | Switzerland | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Jung J.-H. | - |
dc.contributor.googleauthor | Min P.-K. | - |
dc.contributor.googleauthor | Kim J.-Y. | - |
dc.contributor.googleauthor | Park S. | - |
dc.contributor.googleauthor | Choi E.-Y. | - |
dc.contributor.googleauthor | Ko Y.-G. | - |
dc.contributor.googleauthor | Choi D. | - |
dc.contributor.googleauthor | Jang Y. | - |
dc.contributor.googleauthor | Shim W.-H. | - |
dc.contributor.googleauthor | Cho S.-Y. | - |
dc.identifier.doi | 10.1159/000086688 | - |
dc.contributor.localId | A00127 | - |
dc.contributor.localId | A00926 | - |
dc.contributor.localId | A01512 | - |
dc.contributor.localId | A02202 | - |
dc.contributor.localId | A03448 | - |
dc.contributor.localId | A03844 | - |
dc.contributor.localId | A04053 | - |
dc.contributor.localId | A04165 | - |
dc.relation.journalcode | J00457 | - |
dc.identifier.eissn | 1421-9751 | - |
dc.identifier.pmid | 16020923 | - |
dc.identifier.url | http://www.karger.com/Article/FullText/86688 | - |
dc.subject.keyword | Restenosis, coronary | - |
dc.subject.keyword | Carbon | - |
dc.subject.keyword | Inflammation | - |
dc.contributor.alternativeName | Ko, Young Guk | - |
dc.contributor.alternativeName | Kim, Jong Youn | - |
dc.contributor.alternativeName | Park, Sung Ha | - |
dc.contributor.alternativeName | Shim, Won Heum | - |
dc.contributor.alternativeName | Jang, Yang Soo | - |
dc.contributor.alternativeName | Cho, Seung Yun | - |
dc.contributor.alternativeName | Choi, Dong Hoon | - |
dc.contributor.alternativeName | Choi, Eui Young | - |
dc.citation.volume | 104 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 72 | - |
dc.citation.endPage | 75 | - |
dc.identifier.bibliographicCitation | CARDIOLOGY, Vol.104(2) : 72-75, 2005 | - |
dc.date.modified | 2017-05-04 | - |
dc.identifier.rimsid | 43429 | - |
dc.type.rims | ART | - |
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