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Interindividual reproducibility of glutamate quantification using 1.5-T proton magnetic resonance spectroscopy

DC FieldValueLanguage
dc.contributor.author김재진-
dc.contributor.author남궁기-
dc.date.accessioned2017-10-26T06:36:01Z-
dc.date.available2017-10-26T06:36:01Z-
dc.date.issued2005-
dc.identifier.issn0740-3194-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/151065-
dc.description.abstractThe goal of this study was to measure the interindividual reproducibility of glutamate quantification in 1.5-T (1)H MRS of human brains. To determine the effective echo time (TE) for glutamate quantification, spectra from a phantom and 12 participants were obtained with TE = 30, 35, 40, and 144 ms (repetition time (TR) = 2000 ms and volume of interest = 4 cm(3)). The average Cramer-Rao lower bounds for glutamate quantification using LCModel was lowest in two experiments when TE = 40 ms.Twenty-one subjects participated in experiments that measured interindividual reproducibility of glutamate quantification. Spectra were acquired with TR = 6000 ms and TE = 40 ms. Results showed that the coefficients of variance were 11.0 and 13.1% in the anterior cingulate cortex and insula, respectively. This suggests that glutamate can be reproducibly measured from 1.5-T (1)H MRS with long TR, effective TE, and the LCModel.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherWiley-
dc.relation.isPartOfMAGNETIC RESONANCE IN MEDICINE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHBrain/metabolism*-
dc.subject.MESHBrain Chemistry-
dc.subject.MESHGlutamic Acid/metabolism*-
dc.subject.MESHHumans-
dc.subject.MESHMagnetic Resonance Spectroscopy/methods*-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHPhantoms, Imaging-
dc.subject.MESHReproducibility of Results-
dc.titleInterindividual reproducibility of glutamate quantification using 1.5-T proton magnetic resonance spectroscopy-
dc.typeArticle-
dc.publisher.locationUnited States-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Psychiatry (정신과학교실)-
dc.contributor.departmentDept. of Psychiatry (정신과학교실)-
dc.contributor.googleauthorDong-Pyo Jang-
dc.contributor.googleauthorJong-Min Lee-
dc.contributor.googleauthorEun Lee-
dc.contributor.googleauthorSangjin Park-
dc.contributor.googleauthorJae-Jin Kim-
dc.contributor.googleauthorKee Namkoong-
dc.contributor.googleauthorKang-Jun Yoon-
dc.contributor.googleauthorIn-Young Kim-
dc.contributor.googleauthorSun I. Kim-
dc.identifier.doi10.1002/mrm.20387-
dc.contributor.localIdA00870-
dc.contributor.localIdA01240-
dc.relation.journalcodeJ02179-
dc.identifier.eissn1522-2594-
dc.identifier.pmid15723390-
dc.identifier.urlhttp://onlinelibrary.wiley.com/doi/10.1002/mrm.20387/abstract-
dc.subject.keywordglutamate-
dc.subject.keywordreproducibility-
dc.subject.keyword1H MRS-
dc.subject.keywordeffective echo time-
dc.subject.keywordquantification-
dc.contributor.alternativeNameKim, Jae Jin-
dc.contributor.alternativeNameNamkoong, Kee-
dc.citation.volume53-
dc.citation.number3-
dc.citation.startPage708-
dc.citation.endPage712-
dc.identifier.bibliographicCitationMAGNETIC RESONANCE IN MEDICINE, Vol.53(3) : 708-712, 2005-
dc.date.modified2017-05-04-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Psychiatry (정신과학교실) > 1. Journal Papers

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