임신 중 발견된 분화 갑상선암의 수술 시기 선택

Abstract

Purpose: The optimal timing of a surgery for well-differentiated thyroid carcinoma detected during pregnancy remains controversial. This study was performed to determine the optimal timing of surgery for a well-differentiated thyroid carcinoma detected during pregnancy. Methods: Betwwen July 1991 and June 2004, 20 cases diagnosed with a well-differentiated thyroid carcinoma during pregnancy were retrospectively analyzed. All 20 patients had undergone surgery. The patients were divided into three groups according to the timing of their surgery. Group I (n=9) had a thyroidectomy after delivery, group II (n=6) had a thyroidectomy during the second trimester, and group III (n=5) had a thyroidectomy after an abortion. Group III was excluded from the study as our particularly interest was in determining the optimal timing of surgery during pregnancy. Results: No significant differences were noted between groups I and II with regard to age, tumor size, TNM stage and the timing of diagnosis. There were no TNM stage changes in group I, although a slight increase in tumor size during pregnancy was noted. There were no significant differences in the surgical outcomes between groups I and II with regard to types of operation, operation times, perioperative complications, length of hospital stays and treatment outcomes. Conclusion: The treatment of a well-differentiated thyroid carcinoma detected during pregnancy can be delayed until after delivery in most patients.