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폐 전이 유두상 갑상선암의 예후인자 분석

Other Titles
 Analysis of Prognostic Factors in Patients with Pulmonary Metastases from Papillary Thyroid Carcinoma 
Authors
 남기현  ;  윤종호  ;  장항석  ;  박정수 
Citation
 JOURNAL OF THE KOREAN SURGICAL SOCIETY , Vol.68(3) : 178-184, 2005 
Journal Title
JOURNAL OF THE KOREAN SURGICAL SOCIETY (대한외과학회지)
ISSN
 1226-0053 
Issue Date
2005
MeSH
Papillary thyroid carcinoma ; Pulmonary metastasis ; radioactive iodine ; Prognostic factor ; Survival rate
Keywords
Papillary thyroid carcinoma ; Pulmonary metastasis ; radioactive iodine ; Prognostic factor ; Survival rate
Abstract
Purpose: This study aimed to investigate the factors influencing long-term outcome after treatment in patients with pulmonary metastasis from papillary thyroid carcinoma.
Methods: Of the 2,832 patients with papillary thyroid carcinoma who underwent thyroidectomy at Yonsei University Medical Center from 1986∼2003, 51 patients were identified to have a pulmonary metastasis. A retrospective review of 51 patients was done through medical records.
Results: The study group comprised 25 females and 26 males. The mean age at primary diagnosis was 45 years (range, 8∼79 years). Mean follow-up was 36 months after diagnosis of pulmonary metastasis. Disease-specific survival rates at 5 and 10 years were 81% and 48%, respectively. By univariate log-rank survival analyses, age at diagnosis, postoperative radioactive iodine treatment, metastasis at diagnosis, multiple organ involvement, uptake of radioactive iodine by pulmonary metastasis and high dose of radioactive iodine treatment were significant. However, by multivariate Cox-regression analyses, age at diagnosis and high dose of radioactive iodine treatment were proven to be significant influencing factors for survival.
Conclusion: Young age at diagnosis and high dose of radioactive iodine treatment are the most significant prognostic factors positively influencing survival in patients with pulmonary metastasis from papillary thyroid carcinoma.
Files in This Item:
T200500739.pdf Download
DOI
OAK-2005-04246
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
Yonsei Authors
Nam, Kee Hyun(남기현) ORCID logo https://orcid.org/0000-0002-6852-1190
Park, Cheong Soo(박정수)
Chang, Hang Seok(장항석) ORCID logo https://orcid.org/0000-0002-5162-103X
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/151019
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