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경부와 종격동에 발생한 캐슬만씨 병(Castleman's Disease)

Other Titles
 Castleman's Disease of the Neck and Mediastinum 
 남기현  ;  최현호  ;  임치영  ;  이잔디  ;  김승일  ;  장항석  ;  홍순원  ;  박정수 
 Korean Journal of Head & Neck Oncology (대한두경부종양학회지), Vol.21(1) : 48-52, 2005 
Journal Title
Korean Journal of Head & Neck Oncology(대한두경부종양학회지)
Issue Date
castleman's disease ; lymphoproliferative disorder ; neck ; mediastinum
castleman's disease ; lymphoproliferative disorder ; neck ; mediastinum
Objectives: Castleman's disease(CD) is a lymphoproliferative disorder of unknown etiology. To elucidate the clinicopathologic characteristics of CD, we retrospectively reviewed our experience.
Methods: Fifteen patients with CD of the neck and mediastinum were identified. Patients were divided into two groups: group I had an unicentric CD and group II had multicentric CD. The histology of CD was divided into 3 subtypes: hyaline-vascular(HV), plasma cell(PC), and mixed.
Results: The study included 12 cases of group I, 3 cases of group II in the clinical aspect and 10 cases with HV, 3 cases with PC, 2 cases with mixed type in the histologic aspect. Of group I patients who underwent complete surgical excision, all are currently free of disease. The clinical course of group II patients was variable. Of two patients with multicentric plasma cell CD who were treated, one remain free from disease and the other had a local recurrence in the neck. One patient with multicentric mixed CD died of disease after 30 months of presentation.
Conclusion: Surgical resection is recommend for patients with the unicentric CD, regardless of histologic subtype. Patients with multicentric disease do not benefit from surgical resection and should be candidates for multimodality therapy.
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Seung Il(김승일)
Nam, Kee Hyun(남기현) ORCID logo https://orcid.org/0000-0002-6852-1190
Park, Cheong Soo(박정수)
Lee, Jan Dee(이잔디) ORCID logo https://orcid.org/0000-0003-4090-0049
Lim, Chi Young(임치영)
Chang, Hang Seok(장항석) ORCID logo https://orcid.org/0000-0002-5162-103X
Hong, Soon Won(홍순원) ORCID logo https://orcid.org/0000-0002-0324-2414
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