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의식장애를 동반한 고암모니아혈증과 혈청 아미노산이상을 보인 원발성 유전분증 1예

Other Titles
 A Case of Serum Amino Acid Disturbance with Hyperammonemia in Patient with Primary Amyloidosis 
 김유리  ;  김진석  ;  박선영  ;  박인혜  ;  정준원  ;  이승태  ;  민유홍  ;  한지숙  ;  기정혜 
 Korean Journal of Hematology, Vol.40(1) : 54-57, 2005 
Journal Title
 Korean Journal of Hematology 
Issue Date
Amyloidosis ; Amino acid disturbance ; Hyperammonemia
Amyloidosis ; Amino acid disturbance ; Hyperammonemia
There have been reports that hyperammonemia and amino acid disturbance can cause loss of consciousness in patients with multiple myelomas and normal liver function. We experienced a case of a 71-years-old female patient with amyloidosis, who had shown disturbance of consciousness. At that time, the serum ammonia level was elevated; serum amino acids disturbance was also noted. In particular, the decrease in branched-chain amino acids and increase in aromatic amino acids results in a low Fisher ratio. The Fisher ratio, the ratio of branched-chain to aromatic amino acids, has been suggested as an important indicator of consciousness disturbance. We report, for the first time in Korea, a case of amyloidosis, with mental disturbance due to serum amino acid disturbance.
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kie, Jeong Hae(기정혜)
Kim, Yu Ri(김유리) ORCID logo https://orcid.org/0000-0001-5505-0142
Kim, Jin Seok(김진석) ORCID logo https://orcid.org/0000-0001-8986-8436
Min, Yoo Hong(민유홍) ORCID logo https://orcid.org/0000-0001-8542-9583
Park, Sun Young(박선영)
Park, In Hae(박인혜)
Lee, Seung Tae(이승태)
Cheong, June-Won(정준원) ORCID logo https://orcid.org/0000-0002-1744-0921
Hahn, Jee Sook(한지숙)
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