Cited 44 times in
Clinical features of bone metastases resulting from thyroid cancer: A review of 28 patients over a 20-year period
DC Field | Value | Language |
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dc.contributor.author | 김경래 | - |
dc.contributor.author | 김철식 | - |
dc.contributor.author | 남기현 | - |
dc.contributor.author | 도미영 | - |
dc.contributor.author | 박정수 | - |
dc.contributor.author | 안철우 | - |
dc.contributor.author | 이유미 | - |
dc.contributor.author | 이현철 | - |
dc.contributor.author | 임승길 | - |
dc.contributor.author | 차봉수 | - |
dc.date.accessioned | 2017-10-26T06:11:12Z | - |
dc.date.available | 2017-10-26T06:11:12Z | - |
dc.date.issued | 2005 | - |
dc.identifier.issn | 0918-8959 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/150622 | - |
dc.description.abstract | Bone is the second most frequent site of metastasis resulting from thyroid cancer. Many studies have investigated clinical features and prognostic factors of distant metastases stemming from thyroid cancer in Western countries. The purpose of this study was to review clinical characteristics of Korean patients with bone metastasis originating from thyroid cancer. Between January 1985 and August 2004, 28 patients with thyroid cancer were diagnosed with bone metastases at the Yonsei Severance Hospital in Seoul, Korea. Their clinical characteristics were analyzed retrospectively. Incidence of bone metastasis from follicular thyroid cancer was 6.8% (9 of 132 patients), and 0.4% (13 of 3,154 patients) from papillary thyroid cancer, with an odds ratio of 17.67 (95% confidence interval; 7.41-42). Twelve patients had no symptoms of bone metastasis. Overall mean number of metastasis sites was 2.6 +/- 1.9, and 12 patients had a solitary bone metastasis. Survival rates between the synchronous and metachronous metastasis groups were not significantly different, and the number of metastasis sites did not affect survival. However, the survival of patients that underwent curative treatment was longer than those with palliation (P = 0.0317). In Korea, the overall incidence of bone metastasis resulting from thyroid cancer was less than our expectation. Many patients were asymptomatic, and had a tendency of undergoing less aggressive or palliative treatment, even though the long-term survival of distant metastasis resulting from thyroid cancer with active treatment is relatively good. Further studies of the prognostic factors and effectiveness of various treatments of these patients are needed to enhance survival. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | English | - |
dc.publisher | Japan Endocrine Society | - |
dc.relation.isPartOf | ENDOCRINE JOURNAL | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | thyroid cancer | - |
dc.subject.MESH | bone metastasis | - |
dc.subject.MESH | synchronous | - |
dc.subject.MESH | metachronous | - |
dc.title | Clinical features of bone metastases resulting from thyroid cancer: A review of 28 patients over a 20-year period | - |
dc.type | Article | - |
dc.publisher.location | Japan | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.department | Dept. of Surgery (외과학교실) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.department | Dept. of Surgery (외과학교실) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Mi Young DO | - |
dc.contributor.googleauthor | Yumie RHEE | - |
dc.contributor.googleauthor | Dae Jung KIM | - |
dc.contributor.googleauthor | Chul Sik KIM | - |
dc.contributor.googleauthor | Kee Hyun NAM | - |
dc.contributor.googleauthor | Chul Woo AHN | - |
dc.contributor.googleauthor | Bong Soo CHA | - |
dc.contributor.googleauthor | Kyung Rae KIM | - |
dc.contributor.googleauthor | Hyun Chul LEE | - |
dc.contributor.googleauthor | Cheong Soo PARK | - |
dc.contributor.googleauthor | Sung Kil LIM | - |
dc.identifier.doi | 10.1507/endocrj.52.701 | - |
dc.contributor.localId | A00294 | - |
dc.contributor.localId | A01054 | - |
dc.contributor.localId | A01245 | - |
dc.contributor.localId | A01311 | - |
dc.contributor.localId | A01646 | - |
dc.contributor.localId | A02270 | - |
dc.contributor.localId | A03012 | - |
dc.contributor.localId | A03301 | - |
dc.contributor.localId | A03375 | - |
dc.contributor.localId | A03996 | - |
dc.relation.journalcode | J00769 | - |
dc.identifier.eissn | 1348-4540 | - |
dc.identifier.pmid | 10.1507/endocrj.52.701 | - |
dc.subject.keyword | thyroid cancer | - |
dc.subject.keyword | bone metastasis | - |
dc.subject.keyword | synchronous | - |
dc.subject.keyword | metachronous | - |
dc.contributor.alternativeName | Kim, Kyung Rae | - |
dc.contributor.alternativeName | Kim, Chul Sik | - |
dc.contributor.alternativeName | Nam, Kee Hyun | - |
dc.contributor.alternativeName | Do, Mi Yeong | - |
dc.contributor.alternativeName | Park, Cheong Soo | - |
dc.contributor.alternativeName | Ahn, Chul Woo | - |
dc.contributor.alternativeName | Rhee, Yumie | - |
dc.contributor.alternativeName | Lee, Hyun Chul | - |
dc.contributor.alternativeName | Lim, Sung Kil | - |
dc.contributor.alternativeName | Cha, Bong Soo | - |
dc.citation.volume | 52 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 701 | - |
dc.citation.endPage | 707 | - |
dc.identifier.bibliographicCitation | ENDOCRINE JOURNAL, Vol.52(6) : 701-707, 2005 | - |
dc.date.modified | 2017-05-04 | - |
dc.identifier.rimsid | 44195 | - |
dc.type.rims | ART | - |
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