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소아 및 청소년 비만증에서 인슐린 저항성에 미치는 요인
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김덕희 | - |
dc.contributor.author | 김동기 | - |
dc.contributor.author | 김호성 | - |
dc.contributor.author | 차봉수 | - |
dc.contributor.author | 배상욱 | - |
dc.date.accessioned | 2017-09-30T06:32:15Z | - |
dc.date.available | 2017-09-30T06:32:15Z | - |
dc.date.issued | 2005 | - |
dc.identifier.issn | 1738-1061 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/150012 | - |
dc.description.abstract | Purpose: Insulin resistance is the most important risk factor linked to the development of impaired glucose tolerance(IGT), diabetes mellitus and cardiovascular diseases in childhood and adolescent obesity, The purpose of this study was to see whether insulin resistance of obese adolescent is higher than that of obese children. and to analyze gender difference and affecting factors of insulin resistance. Methods: Of the 9,837 school children from 5 to 16 tears old, 92 obese children and 187 adolescent, underwent a two-hour oral glucose tolerance test and plasma glucose, insulin, lipid profiles, leptin and high sensitive C-reactive protein(hs-CRP) were measure. Results: Plasma insulin levels of female were higher compared to those of males during oral glucose tolerance test(P<0.05). Four(4.3%) in obese children and twenty five(13.3%) in obese adolescents met the criteria of IGT. Female, leptin, adiponectin and triglyceride concentrations were strongly correlated with homeostatic model assessment insulin-resistance(HOMA-IR) by multiple linear regression analysis(P<0.05). Conclusion: Obese adolescents might have higher insulin concentrations compared to obese children and obese girls higher insulin concentrations than obese boys. Obese boys and children with impaired glucose tolerance have higher insulin concentrations than those with normal glucose tolerance. HOMA-IR was significantly correlated with female, plasma leptin, adiponectin and triglyceride concentrations. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | Korean | - |
dc.publisher | 대한소아과학회 | - |
dc.relation.isPartOf | Korean Journal of Pediatrics | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Childhood obesity | - |
dc.subject.MESH | Adolescent obesity | - |
dc.subject.MESH | Insulin resistance | - |
dc.subject.MESH | Impaired glucose tolerance | - |
dc.title | 소아 및 청소년 비만증에서 인슐린 저항성에 미치는 요인 | - |
dc.title.alternative | Affecting Factors of Insulin Resistance in Obese Children and Adolescents | - |
dc.type | Article | - |
dc.publisher.location | Korea | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pediatrics (소아청소년과학교실) | - |
dc.contributor.department | Dept. of Biomedical Systems Informatics (의생명시스템정보학교실) | - |
dc.contributor.department | Dept. of Pediatrics (소아청소년과학교실) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | 김덕희 | - |
dc.contributor.googleauthor | 은호선 | - |
dc.contributor.googleauthor | 최인경 | - |
dc.contributor.googleauthor | 김호성 | - |
dc.contributor.googleauthor | 차봉수 | - |
dc.contributor.googleauthor | 김동기 | - |
dc.identifier.doi | OAK-2005-03627 | - |
dc.contributor.localId | A00378 | - |
dc.contributor.localId | A00399 | - |
dc.contributor.localId | A01184 | - |
dc.contributor.localId | A03996 | - |
dc.contributor.localId | A01793 | - |
dc.relation.journalcode | J02100 | - |
dc.identifier.eissn | 2092-7258 | - |
dc.relation.journalsince | 2004~ | - |
dc.relation.journalbefore | ~2003 Korean Journal of Pediatrics | - |
dc.subject.keyword | Childhood obesity | - |
dc.subject.keyword | Adolescent obesity | - |
dc.subject.keyword | Insulin resistance | - |
dc.subject.keyword | Impaired glucose tolerance | - |
dc.contributor.alternativeName | Kim, Duk Hee | - |
dc.contributor.alternativeName | Kim, Dong Ki | - |
dc.contributor.alternativeName | Kim, Ho Seong | - |
dc.contributor.alternativeName | Cha, Bong Soo | - |
dc.contributor.affiliatedAuthor | 배상욱 | - |
dc.citation.volume | 48 | - |
dc.citation.number | 10 | - |
dc.citation.startPage | 1076 | - |
dc.citation.endPage | 1081 | - |
dc.identifier.bibliographicCitation | Korean Journal of Pediatrics, Vol.48(10) : 1076-1081, 2005 | - |
dc.date.modified | 2017-05-04 | - |
dc.identifier.rimsid | 42694 | - |
dc.type.rims | ART | - |
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