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제2형 당뇨병을 동반한 급성기 열공성 뇌경색에서 박동성 지수의 증가

DC FieldValueLanguage
dc.contributor.author남효석-
dc.contributor.author이경열-
dc.contributor.author최영철-
dc.contributor.author한상원-
dc.contributor.author허지회-
dc.date.accessioned2017-05-04T07:40:12Z-
dc.date.available2017-05-04T07:40:12Z-
dc.date.issued2005-
dc.identifier.issn1738-1428-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/147625-
dc.description.abstractBackground: The pulsatility index (PI) measured by a transcranial Doppler (TCD) has been postulated to reflect the vascular resistance that is distal to the artery being examined. Therefore, pathologies of small perforating arteries may affect the PI of the proximal artery. Microangiopathy is a common vascular complication of diabetes mellitus (DM), which may contribute to the development of small infarctions involving the perforating artery, and may be reflected on the PI. Methods: We enrolled patients with acute cerebral infarctions who were examined by TCD, MRI, and MRA and fulfilled the following criteria: 1)an infarction of less than 2 cm size involving a single perforating arterial territory; 2)no significant arterial stenosis on MRA; and 3)no cardioembolic sources. Patients were divided into either a group with DM, or without and TCD findings were compared. Results: The DM group showed higher PI than non-DM (0.99 v.s. 0.85 for the right middle cerebral artery; 1.02 v.s. 0.85 for the left middle cerebral artery; and 0.94 v.s. 0.78 for the basilar artery). The mean flow velocity was comparable between the groups. Multivariate linear regression analysis revealed that the duration of DM was a significant predictor of elevated PI of the bilateral MCA and basilar artery and that age was another significant predictor in the case of basilar artery. Conclusions: The elevated PIs in DM patients suggest the possible role of diabetic microvascular complications in the development of the lacunar infarction. The PI measurement using TCD may be a useful marker of the lacunar infarction, especially in DM patients-
dc.description.statementOfResponsibilityopen-
dc.format.extent457~462-
dc.languageKorean-
dc.publisherKorean Neurological Association-
dc.relation.isPartOfJournal of the Korean Neurological Association-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAged-
dc.subject.MESHBasilar Artery/diagnostic imaging-
dc.subject.MESHBasilar Artery/physiology-
dc.subject.MESHBrain/blood supply*-
dc.subject.MESHBrain Infarction/complications-
dc.subject.MESHBrain Infarction/diagnostic imaging*-
dc.subject.MESHDiabetes Mellitus, Type 2/complications*-
dc.subject.MESHDiabetic Angiopathies/diagnostic imaging*-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHMiddle Cerebral Artery/diagnostic imaging-
dc.subject.MESHMiddle Cerebral Artery/physiology-
dc.subject.MESHPulsatile Flow-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHUltrasonography, Doppler, Transcranial-
dc.title제2형 당뇨병을 동반한 급성기 열공성 뇌경색에서 박동성 지수의 증가-
dc.title.alternativeIncreased Pulsatility Index in Acute Lacunar Infarction with Type II Diabetes-
dc.typeArticle-
dc.publisher.locationKorea-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Neurology (신경과학교실)-
dc.contributor.departmentDept. of Neurology (신경과학교실)-
dc.contributor.departmentDept. of Neurology (신경과학교실)-
dc.contributor.departmentDept. of Neurology (신경과학교실)-
dc.contributor.departmentDept. of Neurology (신경과학교실)-
dc.contributor.googleauthor이기욱-
dc.contributor.googleauthor박지형-
dc.contributor.googleauthor최영철-
dc.contributor.googleauthor한상원-
dc.contributor.googleauthor남효석-
dc.contributor.googleauthor허지회-
dc.contributor.googleauthor이경열-
dc.identifier.doi10.3349/ymj.2007.48.5.802-
dc.contributor.localIdA01273-
dc.contributor.localIdA02648-
dc.contributor.localIdA04116-
dc.contributor.localIdA04284-
dc.contributor.localIdA04369-
dc.relation.journalcodeJ01835-
dc.relation.journalsince2004~-
dc.identifier.pmid17963337-
dc.relation.journalbefore~2003 Journal of the Korean Neurological Association (대한신경과학회지)-
dc.subject.keywordDiabetes mellitus-
dc.subject.keywordlacunar infarction-
dc.subject.keywordtranscranial Doppler-
dc.subject.keywordpulsatility index-
dc.contributor.alternativeNameNam, Hyo Suk-
dc.contributor.alternativeNameLee, Kyung Yul-
dc.contributor.alternativeNameChoi, Young Chul-
dc.contributor.alternativeNameHan, Sang Won-
dc.contributor.alternativeNameHeo, Ji Hoe-
dc.citation.volume23-
dc.citation.number4-
dc.citation.startPage457-
dc.citation.endPage462-
dc.identifier.bibliographicCitationJournal of the Korean Neurological Association, Vol.23(4) : 457-462, 2005-
dc.date.modified2017-05-04-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurology (신경과학교실) > 1. Journal Papers

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