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Severity of ultrasonographic liver steatosis and metabolic syndrome in Korean men and women

DC FieldValueLanguage
dc.contributor.author김현창-
dc.contributor.author이현철-
dc.contributor.author허갑범-
dc.date.accessioned2017-05-04T07:39:00Z-
dc.date.available2017-05-04T07:39:00Z-
dc.date.issued2005-
dc.identifier.issn1007-9327-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/147590-
dc.description.abstractAIM: To evaluate the association between the severity of liver steatosis and metabolic syndrome in apparently healthy Korean adults. METHODS: We examined 1 022 men and women, aged 30-79 years, who participated in a health screening test. A standard interview, anthropometrics, biochemical studies, and abdominal ultrasonography were conducted for each participant. Metabolic syndrome was defined according to the National Cholesterol Education Program Adult Treatment Panel III, with a modification for the waist circumference cut-off level. The severity of liver steatosis was evaluated using liver ultrasonography, and serum aspartate aminotransferase (AST), alanine aminotransferase (ALT), and gamma-glutamyl transferase (gamma-GT) levels were determined. RESULTS: Ultrasonographic liver steatosis was strongly associated with metabolic syndrome and common metabolic abnormalities. Compared with people without steatosis, people with mild, moderate, and severe steatosis had adjusted odds ratios for metabolic syndrome of 1.72 (95%CI, 1.01-2.94), 2.89 (1.75-4.76) and 3.53 (1.25-9.98) in men, and 2.86 (1.64-5.01), 3.19 (1.80-5.65) and 3.70 (0.82-16.73) in women, respectively. The serum AST level was not associated with metabolic syndrome. The serum ALT and gamma-GT levels were significantly associated with metabolic syndrome in men but not in women. CONCLUSION: The occurrence of metabolic syndrome shows a stronger association with the severity of ultrasonographic steatosis than with the serum liver enzyme levels. The degree of fatty infiltration detected on ultrasonography can be used as an indicator of liver dysfunction attributable to metabolic abnormalities.-
dc.description.statementOfResponsibilityopen-
dc.formatapplication/pdf-
dc.languageEnglish-
dc.publisherBaishideng Publishing Group-
dc.relation.isPartOfWORLD JOURNAL OF GASTROENTEROLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHFatty Liver/complications*-
dc.subject.MESHFatty Liver/diagnostic imaging*-
dc.subject.MESHFatty Liver/epidemiology-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHKorea/epidemiology-
dc.subject.MESHMale-
dc.subject.MESHMetabolic Syndrome/complications*-
dc.subject.MESHMetabolic Syndrome/epidemiology-
dc.subject.MESHMiddle Aged-
dc.subject.MESHRisk Factors-
dc.subject.MESHSeverity of Illness Index*-
dc.subject.MESHUltrasonography-
dc.titleSeverity of ultrasonographic liver steatosis and metabolic syndrome in Korean men and women-
dc.typeArticle-
dc.publisher.locationUnited States-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Preventive Medicine and Public Health (예방의학교실)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.googleauthorHyeon Chang Kim-
dc.contributor.googleauthorSung Hee Choi-
dc.contributor.googleauthorHae Won Shin-
dc.contributor.googleauthorJae Youn Cheong-
dc.contributor.googleauthorKwan Woo Lee-
dc.contributor.googleauthorHyun Chul Lee-
dc.contributor.googleauthorKap Bum Huh-
dc.contributor.googleauthorDae Jung Kim-
dc.identifier.doiOAK-2005-03294-
dc.contributor.localIdA01142-
dc.contributor.localIdA03301-
dc.contributor.localIdA04339-
dc.relation.journalcodeJ02795-
dc.identifier.eissn2219-2840-
dc.identifier.pmid16149138-
dc.subject.keywordMetabolic syndrome-
dc.subject.keywordLiver steatosis-
dc.subject.keywordNon-alcoholic fatty liver disease-
dc.subject.keywordUltrasonography-
dc.contributor.alternativeNameKim, Hyeon Chang-
dc.contributor.alternativeNameLee, Hyun Chul-
dc.contributor.alternativeNameHuh, Kap Bum-
dc.citation.volume11-
dc.citation.number34-
dc.citation.startPage5314-
dc.citation.endPage5321-
dc.identifier.bibliographicCitationWORLD JOURNAL OF GASTROENTEROLOGY, Vol.11(34) : 5314-5321, 2005-
dc.date.modified2017-05-04-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Preventive Medicine and Public Health (예방의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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