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한국에서 발생한 플라스미드성 CMY-2 β-lactamase 생성 Escherichia coli
DC Field | Value | Language |
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dc.contributor.author | 이경원 | - |
dc.date.accessioned | 2017-05-04T07:34:23Z | - |
dc.date.available | 2017-05-04T07:34:23Z | - |
dc.date.issued | 2005 | - |
dc.identifier.issn | 1598-6535 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/147481 | - |
dc.description.abstract | Background :Of the plasmid-mediated AmpC -lactamases (ABLs), CMY-2 is the most prevalent and is distributed in many countries. However, little is known about the emergence and characteristics of CMY-2 among Escherichia coli isolates in Korea. The aims of this study were to detect the emergence of the CMY-2 -lactamase in clinical isolates of E. coli from various regions in Korea. Method :Eighteen cefoxitin non-susceptible isolates of 1,130 consecutive, nonrepeat isolates of E. coli at five university hospitals were tested for antimicrobial susceptibility by the broth microdilution method. The cefoxitin non-susceptible isolates were further investigated by AmpC disk tests, double disk synergy (DDS) tests, isoelectric focusing, CMY-2-specific PCR, DNA sequencing, and plasmid analysis. Result :Seven (0.6%) isolates of plasmid-mediated ABL-producing E. coli were found at three of the five hospitals; all seven isolates produced CMY-2 -lactamase and one of the isolates was also tested positive by the DDS test. All isolates demonstrated different plasmid patterns by plasmid analysis. Conclusion :Our data indicate that CMY-2-producing E. coli has emerged and is prevalent in the medical institution in Korea. Therefore, constant surveillance is needed to prevent its further spread. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 98~103 | - |
dc.language | Korean | - |
dc.publisher | 대한진단검사의학회 | - |
dc.relation.isPartOf | KOREAN JOURNAL OF LABORATORY MEDICINE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Plasmid-mediated AmpC -lactamase | - |
dc.subject.MESH | Escherichia coli | - |
dc.subject.MESH | CMY-2 | - |
dc.title | 한국에서 발생한 플라스미드성 CMY-2 β-lactamase 생성 Escherichia coli | - |
dc.title.alternative | Emergence of Plasmid-Mediated CMY-2 -Lactamase Produced by Clinical Isolates of Escherichia coli in Korea | - |
dc.type | Article | - |
dc.publisher.location | Korea | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Laboratory Medicine (진단검사의학교실) | - |
dc.contributor.googleauthor | 이창훈 | - |
dc.contributor.googleauthor | 김재석 | - |
dc.contributor.googleauthor | 어영 | - |
dc.contributor.googleauthor | 이종욱 | - |
dc.contributor.googleauthor | 이경원 | - |
dc.contributor.googleauthor | 송원근 | - |
dc.identifier.doi | OAK-2005-02958 | - |
dc.contributor.localId | A02649 | - |
dc.relation.journalcode | J02045 | - |
dc.relation.journalsince | 2002~2006 | - |
dc.relation.journalafter | 2006~ Korean Journal of Laboratory Medicine | - |
dc.relation.journalbefore | ~2005 Korean Journal of Clinical Pathology (대한임상병리학회지) | - |
dc.subject.keyword | Plasmid-mediated AmpC -lactamase | - |
dc.subject.keyword | Escherichia coli | - |
dc.subject.keyword | CMY-2 | - |
dc.contributor.alternativeName | Lee, Kyung Won | - |
dc.citation.volume | 25 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 98 | - |
dc.citation.endPage | 103 | - |
dc.identifier.bibliographicCitation | KOREAN JOURNAL OF LABORATORY MEDICINE , Vol.25(2) : 98-103, 2005 | - |
dc.date.modified | 2017-05-04 | - |
dc.identifier.rimsid | 40261 | - |
dc.type.rims | ART | - |
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