Cited 59 times in
Occurrence of extended-spectrum β-lactamases among chromosomal AmpC-producing Enterobacter cloacae, Citrobacter freundii, and Serratia marcescens in Korea and investigation of screening criteria
DC Field | Value | Language |
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dc.contributor.author | 이경원 | - |
dc.date.accessioned | 2017-05-04T07:31:07Z | - |
dc.date.available | 2017-05-04T07:31:07Z | - |
dc.date.issued | 2005 | - |
dc.identifier.issn | 0732-8893 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/147402 | - |
dc.description.abstract | We assessed the occurrence and screening criterion for extended-spectrum β-lactamases (ESBLs) among AmpC-producing Enterobacter cloacae, Citrobacter freundii, and Serratia marcescens. The 413 isolates (158 E. cloacae, 126 C. freundii, and 129 S. marcescens) isolated from 11 clinical laboratories in Korea were investigated. ESBL production was confirmed by double-disk synergy test and inhibitor-potentiated diffusion test using ceftazidime (CAZ), cefotaxime (CTX), aztreonam (AZT), and cefepime (FEP) with or without clavulanic acid. One hundred seven isolates (25.9%) were as ESBL producers. Of them, resistance was transferred by conjugation in 82 isolates. In transconjugants, structural genes for CTX-M (53.7%), TEM (46.3%), SHV (29.3%) were found. To evaluate the ESBL screening minimum inhibitory concentration (MIC) criteria, MICs for cefuroxime, CAZ, CTX, AZT, and FEP were determined and cutoff value was selected using receiver operator characteristic curve. The FEP MIC ≥ 1 μg/mL had the highest sensitivity (95.3%), specificity (82.7%), and positive (65.8%) and negative predictive values (98.3%). | - |
dc.description.statementOfResponsibility | restriction | - |
dc.format.extent | 265~269 | - |
dc.language | English | - |
dc.publisher | Elsevier Biomedical | - |
dc.relation.isPartOf | DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Anti-Bacterial Agents/pharmacology | - |
dc.subject.MESH | Bacterial Proteins/biosynthesis* | - |
dc.subject.MESH | Cefepime | - |
dc.subject.MESH | Cephalosporins/pharmacology | - |
dc.subject.MESH | Chromosomes, Bacterial | - |
dc.subject.MESH | Citrobacter freundii/drug effects | - |
dc.subject.MESH | Citrobacter freundii/enzymology* | - |
dc.subject.MESH | Citrobacter freundii/genetics | - |
dc.subject.MESH | Conjugation, Genetic | - |
dc.subject.MESH | Enterobacter cloacae/drug effects | - |
dc.subject.MESH | Enterobacter cloacae/enzymology* | - |
dc.subject.MESH | Enterobacter cloacae/genetics | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Korea | - |
dc.subject.MESH | Microbial Sensitivity Tests/methods | - |
dc.subject.MESH | Microbial Sensitivity Tests/standards | - |
dc.subject.MESH | Polymerase Chain Reaction | - |
dc.subject.MESH | Sensitivity and Specificity | - |
dc.subject.MESH | Serratia marcescens/drug effects | - |
dc.subject.MESH | Serratia marcescens/enzymology* | - |
dc.subject.MESH | Serratia marcescens/genetics | - |
dc.subject.MESH | beta-Lactam Resistance | - |
dc.subject.MESH | beta-Lactamases/biosynthesis* | - |
dc.subject.MESH | beta-Lactamases/genetics | - |
dc.subject.MESH | beta-Lactamases/metabolism* | - |
dc.title | Occurrence of extended-spectrum β-lactamases among chromosomal AmpC-producing Enterobacter cloacae, Citrobacter freundii, and Serratia marcescens in Korea and investigation of screening criteria | - |
dc.type | Article | - |
dc.publisher.location | United States | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Laboratory Medicine (진단검사의학교실) | - |
dc.contributor.googleauthor | Yeon-Joon Park | - |
dc.contributor.googleauthor | Sun Young Park | - |
dc.contributor.googleauthor | Eun-Jee Oh | - |
dc.contributor.googleauthor | Jung-Jun Park | - |
dc.contributor.googleauthor | Kyo-Young Lee | - |
dc.contributor.googleauthor | Gun-Jo Woo | - |
dc.contributor.googleauthor | Kyungwon Lee | - |
dc.identifier.doi | 10.1016/j.diagmicrobio.2004.11.009 | - |
dc.contributor.localId | A02649 | - |
dc.relation.journalcode | J00731 | - |
dc.identifier.eissn | 1879-0070 | - |
dc.identifier.pmid | 15808318 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0732889304002354 | - |
dc.subject.keyword | Extended-spectrum β-lactamase | - |
dc.subject.keyword | Enterobacter cloacae | - |
dc.subject.keyword | Citrobacter freundii | - |
dc.subject.keyword | Serratia marcescens | - |
dc.subject.keyword | Screening criteria | - |
dc.contributor.alternativeName | Lee, Kyung Won | - |
dc.citation.volume | 51 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 265 | - |
dc.citation.endPage | 269 | - |
dc.identifier.bibliographicCitation | DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, Vol.51(4) : 265-269, 2005 | - |
dc.date.modified | 2017-05-04 | - |
dc.identifier.rimsid | 48573 | - |
dc.type.rims | ART | - |
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