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The Role of Gastric Distention in Differentiating Recurrent Tumor from Physiologic Uptake in the Remnant Stomach on 18F-FDG PET
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 유영훈 | - |
dc.contributor.author | 윤미진 | - |
dc.contributor.author | 이종두 | - |
dc.date.accessioned | 2017-05-04T07:26:14Z | - |
dc.date.available | 2017-05-04T07:26:14Z | - |
dc.date.issued | 2005 | - |
dc.identifier.issn | 0161-5505 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/147286 | - |
dc.description.abstract | Physiologic (18)F-FDG uptake in the stomach can often cause false-positive results and lowers the usefulness of (18)F-FDG PET in evaluating the remnant stomach. We assessed the role of gastric distension to see whether it is beneficial for the differentiation of recurrent tumors from physiologic (18)F-FDG uptake in the remnant stomach. METHODS: Thirty patients (22 men and 8 women; age range, 27-80 y; mean age, 58.3 y) with a history of subtotal gastrectomy for gastric cancer underwent (18)F-FDG PET for various clinical indications. After whole-body imaging, the patients were asked to drink water, and then spot imaging of the stomach was performed. (18)F-FDG uptake in the remnant stomach was considered positive for malignancy if it was persistently increased, whether focal or diffuse, after water ingestion. We used 2 standardized uptake value (SUV) criteria to differentiate benign from malignant uptake. First, a lesion was considered benign if its SUV was less than 2 on whole-body imaging. Second, for a lesion with an SUV of 2 or above, it was classified as benign if SUV decreased by more than 10% after water ingestion. RESULTS: Visual analysis of whole-body images produced 9 true-negative, 4 false-positive, 16 true-positive, and 1 false-negative results. Use of additional spot images produced 12 true-negative, 1 false-positive, 15 true-positive, and 2 false-negative results. When an SUV cutoff of 2 was applied for malignancy before water ingestion, all 17 patients with local recurrence were correctly identified, but 11 of the 13 patients without local recurrence were falsely considered to have a recurrent tumor in the remnant stomach. To reduce the false-positive results, we used the second SUV criterion after water ingestion. Use of that criterion produced 4 false-negative results although it correctly identified the 11 false-positive results as true negative. CONCLUSION: Gastric distension by having patients drink a glass of water seems to be a simple, cost-effective way of improving the diagnostic accuracy of (18)F-FDG PET in patients with suspected recurrence in the remnant stomach. Visual analysis with special attention to the configuration of (18)F-FDG activity after water ingestion seems to be more useful than the change in SUV in evaluating the remnant stomach. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | English | - |
dc.publisher | Society of Nuclear Medicine | - |
dc.relation.isPartOf | JOURNAL OF NUCLEAR MEDICINE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adenocarcinoma/diagnosis* | - |
dc.subject.MESH | Adenocarcinoma/diagnostic imaging | - |
dc.subject.MESH | Adenocarcinoma/metabolism | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Diagnosis, Differential | - |
dc.subject.MESH | False Positive Reactions | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Fluorine Radioisotopes/pharmacokinetics | - |
dc.subject.MESH | Fluorodeoxyglucose F18*/pharmacokinetics | - |
dc.subject.MESH | Gastrectomy | - |
dc.subject.MESH | Gastric Stump/diagnostic imaging* | - |
dc.subject.MESH | Gastric Stump/physiopathology | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Neoplasm Recurrence, Local/diagnosis* | - |
dc.subject.MESH | Neoplasm Recurrence, Local/diagnostic imaging | - |
dc.subject.MESH | Neoplasm Recurrence, Local/metabolism | - |
dc.subject.MESH | Positron-Emission Tomography | - |
dc.subject.MESH | Radiopharmaceuticals*/pharmacokinetics | - |
dc.subject.MESH | Stomach Neoplasms/diagnosis* | - |
dc.subject.MESH | Stomach Neoplasms/diagnostic imaging | - |
dc.subject.MESH | Stomach Neoplasms/metabolism | - |
dc.subject.MESH | Whole-Body Counting | - |
dc.title | The Role of Gastric Distention in Differentiating Recurrent Tumor from Physiologic Uptake in the Remnant Stomach on 18F-FDG PET | - |
dc.type | Article | - |
dc.publisher.location | United States | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Nuclear Medicine (핵의학교실) | - |
dc.contributor.department | Dept. of Nuclear Medicine (핵의학교실) | - |
dc.contributor.department | Dept. of Nuclear Medicine (핵의학교실) | - |
dc.contributor.googleauthor | Mijin Yun | - |
dc.contributor.googleauthor | Hyun Seok Choi | - |
dc.contributor.googleauthor | Eunhye Yoo | - |
dc.contributor.googleauthor | Jung Kyun Bong | - |
dc.contributor.googleauthor | Young Hoon Ryu | - |
dc.contributor.googleauthor | Jong Doo Lee | - |
dc.identifier.doi | OAK-2005-02359 | - |
dc.contributor.localId | A02485 | - |
dc.contributor.localId | A02550 | - |
dc.contributor.localId | A03138 | - |
dc.relation.journalcode | J01644 | - |
dc.identifier.eissn | 1535-5667 | - |
dc.identifier.pmid | 15937305 | - |
dc.subject.keyword | 15937305 | - |
dc.contributor.alternativeName | Ryu, Young Hoon | - |
dc.contributor.alternativeName | Yun, Mi Jin | - |
dc.contributor.alternativeName | Lee, Jong Doo | - |
dc.citation.volume | 46 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 953 | - |
dc.citation.endPage | 957 | - |
dc.identifier.bibliographicCitation | JOURNAL OF NUCLEAR MEDICINE, Vol.46(6) : 953-957, 2005 | - |
dc.date.modified | 2017-05-04 | - |
dc.identifier.rimsid | 48459 | - |
dc.type.rims | ART | - |
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