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임상검체 및 닭에서 분리된 반코마이신 내성 장구균의 항균제 감수성과 분자역학적 성상 : 임상검체와 닭에서 분리된 반코마이신 내성 장구균의 연관성

DC FieldValueLanguage
dc.contributor.author용동은-
dc.contributor.author이경원-
dc.contributor.author이혁민-
dc.contributor.author정윤섭-
dc.date.accessioned2017-05-04T07:25:38Z-
dc.date.available2017-05-04T07:25:38Z-
dc.date.issued2005-
dc.identifier.issn1598-6535-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/147274-
dc.description.abstractBackground :Enterococcal infections have become extremely difficult to manage because of an increase in antibiotic resistance among enterococci. In Europe, the use of avoparcin in animals was reported to be the cause of vancomycin-resistant enterococci (VRE) transmission to humans. In this study, we performed antimicrobial susceptibility testing and pulsed-field gel electrophoresis (PFGE) to characterize the genetic relatedness of VRE of human and chicken. Method :Ninety strains of VRE were isolated from clinical specimens in three University hospitals located in Seoul and Kyungi province in 2001-2002. Thirty isolates of VRE were collected from four chicken farms located in areas remotely distanced from each other. The isolates were identified to the species level by conventional biochemical tests and commercial kits. Antimicrobial susceptibilities were tested by the NCCLS disk diffusion and agar dilution methods. For a molecular epidemiologic analysis, PFGE was performed. Result :Among the 90 clinical isolates were 73 vancomycin-resistant Enterococcus faecium (VREFM) and 17 vancomycin-resistant E. faecalis (VREFA). The resistant rates of VREFA to ampicillin, levofloxacin and tetracycline were 0%, 100%, and 100%, respectively, and for VREFM, 100%, 96%, and 26%, respectively. However, the resistant rates of VREFM isolated from chicken were 19% to ampicillin, 0% to levofloxacin, and 100% to tetracycline. The PFGE patterns of genomic DNA of the clinical isolates were very diverse, suggesting a polyclonal spread of VRE, although some isolates had an identical PFGE pattern, indicating a mini-outbreak due to a clonal spread. The PFGE patterns of genomic DNA of the chicken isolates were very different from those of the human isolates. Conclusion :VRE isolates from human and chicken showed very different antimicrobial susceptibilities and PFGE patterns. These results suggest that VRE isolated from human and chicken are not closely related genetically.-
dc.description.statementOfResponsibilityopen-
dc.format.extent39~45-
dc.languageKorean-
dc.publisher대한진단검사의학회-
dc.relation.isPartOfKOREAN JOURNAL OF LABORATORY MEDICINE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHVRE-
dc.subject.MESHEpidemiology-
dc.subject.MESHVancomycin-
dc.subject.MESHAntimicrobial susceptibility-
dc.subject.MESHChicken-
dc.title임상검체 및 닭에서 분리된 반코마이신 내성 장구균의 항균제 감수성과 분자역학적 성상 : 임상검체와 닭에서 분리된 반코마이신 내성 장구균의 연관성-
dc.title.alternativeAntimicrobial Susceptibities and PFGE Patterns of Vancomycin-Resistant Enterococcus isolated from Clinical Specimens and Chickens-
dc.typeArticle-
dc.publisher.locationKorea-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Laboratory Medicine (진단검사의학교실)-
dc.contributor.departmentDept. of Laboratory Medicine (진단검사의학교실)-
dc.contributor.departmentDept. of Laboratory Medicine (진단검사의학교실)-
dc.contributor.departmentDept. of Laboratory Medicine (진단검사의학교실)-
dc.contributor.googleauthor이혁민-
dc.contributor.googleauthor용동은-
dc.contributor.googleauthor김명숙-
dc.contributor.googleauthor염종화-
dc.contributor.googleauthor이위교-
dc.contributor.googleauthor허지영-
dc.contributor.googleauthor이동건-
dc.contributor.googleauthor김승한-
dc.contributor.googleauthor유진홍-
dc.contributor.googleauthor이경원-
dc.contributor.googleauthor신완식-
dc.contributor.googleauthor정윤섭-
dc.identifier.doiOAK-2005-02315-
dc.contributor.localIdA02423-
dc.contributor.localIdA02649-
dc.contributor.localIdA03286-
dc.contributor.localIdA03679-
dc.relation.journalcodeJ02045-
dc.relation.journalsince2002~2006-
dc.relation.journalafter2006~ Korean Journal of Laboratory Medicine-
dc.relation.journalbefore~2005 Korean Journal of Clinical Pathology (대한임상병리학회지)-
dc.subject.keywordVRE-
dc.subject.keywordEpidemiology-
dc.subject.keywordVancomycin-
dc.subject.keywordAntimicrobial susceptibility-
dc.subject.keywordChicken-
dc.contributor.alternativeNameYong, Dong Eun-
dc.contributor.alternativeNameLee, Kyung Won-
dc.contributor.alternativeNameLee, Hyuk Min-
dc.contributor.alternativeNameChong, Yun Sop-
dc.citation.volume25-
dc.citation.number1-
dc.citation.startPage39-
dc.citation.endPage45-
dc.identifier.bibliographicCitationKOREAN JOURNAL OF LABORATORY MEDICINE , Vol.25(1) : 39-45, 2005-
dc.date.modified2017-05-04-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers

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