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Preoperative defining system for pancreatic head cancer considering surgical resection
DC Field | Value | Language |
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dc.contributor.author | 강창무 | - |
dc.contributor.author | 이우정 | - |
dc.contributor.author | 황호경 | - |
dc.date.accessioned | 2017-02-27T08:26:06Z | - |
dc.date.available | 2017-02-27T08:26:06Z | - |
dc.date.issued | 2016 | - |
dc.identifier.issn | 1007-9327 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/147184 | - |
dc.description.abstract | AIM: To provide appropriate treatment, it is crucial to share the clinical status of pancreas head cancer among multidisciplinary treatment members. METHODS: A retrospective analysis of the medical records of 113 patients who underwent surgery for pancreas head cancer from January 2008 to December 2012 was performed. We developed preoperative defining system of pancreatic head cancer by describing "resectability - tumor location - vascular relationship - adjacent organ involvement - preoperative CA19-9 (initial bilirubin level) - vascular anomaly". The oncologic correlations with this reporting system were evaluated. RESULTS: Among 113 patients, there were 75 patients (66.4%) with resectable, 34 patients (30.1%) with borderline resectable, and 4 patients (3.5%) with locally advanced pancreatic cancer. Mean disease-free survival was 24.8 mo (95%CI: 19.6-30.1) with a 5-year disease-free survival rate of 13.5%. Pretreatment tumor size ≥ 2.4 cm [Exp(B) = 3.608, 95%CI: 1.512-8.609, P = 0.044] and radiologic vascular invasion [Exp(B) = 5.553, 95%CI: 2.269-14.589, P = 0.002] were independent predictive factors for neoadjuvant treatment. Borderline resectability [Exp(B) = 0.222, P = 0.008], pancreatic head cancer involving the pancreatic neck [Exp(B) = 9.461, P = 0.001] and arterial invasion [Exp(B) = 6.208, P = 0.010], and adjusted CA19-9 ≥ 50 [Exp(B) = 1.972 P = 0.019] were identified as prognostic clinical factors to predict tumor recurrence. CONCLUSION: The suggested preoperative defining system can help with designing treatment plans and also predict oncologic outcomes. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | English | - |
dc.publisher | Baishideng Publishing Group | - |
dc.relation.isPartOf | WORLD JOURNAL OF GASTROENTEROLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | CA-19-9 Antigen/metabolism | - |
dc.subject.MESH | Carcinoma, Pancreatic Ductal/diagnostic imaging | - |
dc.subject.MESH | Carcinoma, Pancreatic Ductal/metabolism | - |
dc.subject.MESH | Carcinoma, Pancreatic Ductal/pathology | - |
dc.subject.MESH | Carcinoma, Pancreatic Ductal/surgery* | - |
dc.subject.MESH | Disease-Free Survival | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Logistic Models | - |
dc.subject.MESH | Multivariate Analysis | - |
dc.subject.MESH | Neoadjuvant Therapy | - |
dc.subject.MESH | Neoplasm Invasiveness | - |
dc.subject.MESH | Neoplasm Staging | - |
dc.subject.MESH | Pancreatic Neoplasms/diagnostic imaging | - |
dc.subject.MESH | Pancreatic Neoplasms/metabolism | - |
dc.subject.MESH | Pancreatic Neoplasms/pathology | - |
dc.subject.MESH | Pancreatic Neoplasms/surgery* | - |
dc.subject.MESH | Pancreaticoduodenectomy | - |
dc.subject.MESH | Preoperative Period | - |
dc.subject.MESH | Prognosis | - |
dc.subject.MESH | Proportional Hazards Models | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Tumor Burden | - |
dc.title | Preoperative defining system for pancreatic head cancer considering surgical resection | - |
dc.type | Article | - |
dc.publisher.location | United States | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Surgery | - |
dc.contributor.googleauthor | Seok Jeong Yang | - |
dc.contributor.googleauthor | Ho Kyoung Hwang | - |
dc.contributor.googleauthor | Chang Moo Kang | - |
dc.contributor.googleauthor | Woo Jung Lee | - |
dc.identifier.doi | 10.3748/wjg.v22.i26.6076 | - |
dc.contributor.localId | A00088 | - |
dc.contributor.localId | A02290 | - |
dc.contributor.localId | A02993 | - |
dc.contributor.localId | A04497 | - |
dc.relation.journalcode | J02795 | - |
dc.identifier.eissn | 2219-2840 | - |
dc.identifier.pmid | 27468199 | - |
dc.subject.keyword | Adjusted CA19-9 | - |
dc.subject.keyword | Borderline resectable | - |
dc.subject.keyword | Neoadjuvant therapy | - |
dc.subject.keyword | Pancreas head cancer | - |
dc.subject.keyword | Preoperative defining system | - |
dc.contributor.alternativeName | Kang, Chang Moo | - |
dc.contributor.alternativeName | Lee, Woo Jung | - |
dc.contributor.alternativeName | Hwang, Ho Kyoung | - |
dc.contributor.affiliatedAuthor | Kang, Chang Moo | - |
dc.contributor.affiliatedAuthor | Yang, Seok Jeong | - |
dc.contributor.affiliatedAuthor | Lee, Woo Jung | - |
dc.contributor.affiliatedAuthor | Hwang, Ho Kyoung | - |
dc.citation.volume | 22 | - |
dc.citation.number | 26 | - |
dc.citation.startPage | 6076 | - |
dc.citation.endPage | 6082 | - |
dc.identifier.bibliographicCitation | WORLD JOURNAL OF GASTROENTEROLOGY, Vol.22(26) : 6076-6082, 2016 | - |
dc.date.modified | 2017-02-24 | - |
dc.identifier.rimsid | 47601 | - |
dc.type.rims | ART | - |
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