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Clinical Significance of Component Allergens in Fagales Pollen-Sensitized Peanut Allergy in Korea.

DC Field Value Language
dc.contributor.author박경희-
dc.contributor.author손영웅-
dc.contributor.author심다운-
dc.contributor.author이상철-
dc.contributor.author이재현-
dc.contributor.author박중원-
dc.contributor.author박혜정-
dc.date.accessioned2017-02-27T08:19:43Z-
dc.date.available2017-02-27T08:19:43Z-
dc.date.issued2016-
dc.identifier.issn2092-7355-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/147155-
dc.description.abstractPURPOSE: Clinical features of peanut allergy can range from localized to systemic reactions. Because peanut and birch pollen have cross-reactivity, peanut can lead to localized allergic reaction in Fagales pollen-sensitized oral allergy syndrome (OAS) patients without peanut sensitization per se. The purpose of this study was to discriminate true peanut food allergy from cross-reactive hypersensitivity in birch-sensitized peanut allergy. METHODS: Birch-sensitized (n=81) and peanut anaphylaxis patients (n=12) were enrolled. Peanut-related allergic reactions and sensitization profiles were examined. Specific IgE to Fagales tree pollens (birch, oak), peanut, and their component allergens (Bet v 1, Bet v 2, Ara h 1, Ara h 2, Ara h 3, Ara h 8, and Ara h 9) were evaluated. Based on these specific IgEs and clinical features, the patients were classified into 4 groups: group 1 (Fagales pollen allergy without OAS), group 2 (Fagales pollen allergy with OAS), group 3 (OAS with peanut anaphylaxis), and group 4 (peanut anaphylaxis). RESULTS: After peanut consumption, one-third of OAS patients experienced oral symptoms not associated with peanut sensitization. Ara h 1 or Ara h 2 was positive in peanut anaphylaxis patients, whereas Ara h 8 was positive in OAS patients. There were 4 patients with both peanut anaphylaxis and OAS (group 3). Both Ara h 2 and Ara h 8 were positive in these patients. Foods associated with OAS in Korea showed unique patterns compared to Westernized countries. CONCLUSIONS: Ara h 2 and Ara h 8 may be important component allergens for discriminating peanut allergy.-
dc.description.statementOfResponsibilityopen-
dc.format.extent505~511-
dc.publisherKorean Academy of Pediatric Allergy and Respiratory Disease-
dc.relation.isPartOfALLERGY ASTHMA & IMMUNOLOGY RESEARCH-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleClinical Significance of Component Allergens in Fagales Pollen-Sensitized Peanut Allergy in Korea.-
dc.typeArticle-
dc.publisher.locationKorea-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Internal Medicine-
dc.contributor.googleauthorKyung Hee Park-
dc.contributor.googleauthorYoung Woong Son-
dc.contributor.googleauthorSang Chul Lee-
dc.contributor.googleauthorKyunguk Jeong-
dc.contributor.googleauthorDa Woon Sim-
dc.contributor.googleauthorHye Jung Park-
dc.contributor.googleauthorSooyoung Lee-
dc.contributor.googleauthorJae-Hyun Lee-
dc.contributor.googleauthorJung-Won Park-
dc.identifier.doi10.4168/aair.2016.8.6.505-
dc.contributor.localIdA01427-
dc.contributor.localIdA04588-
dc.contributor.localIdA04598-
dc.contributor.localIdA02831-
dc.contributor.localIdA03086-
dc.contributor.localIdA01681-
dc.contributor.localIdA01769-
dc.relation.journalcodeJ00064-
dc.identifier.eissn2092-7363-
dc.identifier.pmid27582401-
dc.subject.keywordAllergens-
dc.subject.keywordIgE-
dc.subject.keywordpeanut hypersensitivity-
dc.subject.keywordpollen-
dc.subject.keywordtrees-
dc.contributor.alternativeNamePark, Kyung Hee-
dc.contributor.alternativeNameSon, Young Woong-
dc.contributor.alternativeNameSim, Da Woon-
dc.contributor.alternativeNameLee, Sang Chul-
dc.contributor.alternativeNameLee, Jae Hyun-
dc.contributor.alternativeNamePark, Jung Won-
dc.contributor.alternativeNamePark, Hye Jung-
dc.contributor.affiliatedAuthorPark, Kyung Hee-
dc.contributor.affiliatedAuthorSon, Young Woong-
dc.contributor.affiliatedAuthorSim, Da Woon-
dc.contributor.affiliatedAuthorLee, Sang Chul-
dc.contributor.affiliatedAuthorLee, Jae Hyun-
dc.contributor.affiliatedAuthorPark, Jung Won-
dc.contributor.affiliatedAuthorPark, Hye Jung-
dc.citation.volume8-
dc.citation.number6-
dc.citation.startPage505-
dc.citation.endPage511-
dc.identifier.bibliographicCitationALLERGY ASTHMA & IMMUNOLOGY RESEARCH, Vol.8(6) : 505-511, 2016-
dc.date.modified2017-02-24-
dc.identifier.rimsid47186-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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