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Current status of active surveillance in prostate cancer.

Authors
 Mun Su Chung  ;  Seung Hwan Lee 
Citation
 INVESTIGATIVE AND CLINICAL UROLOGY, Vol.57(1) : 14-20, 2016 
Journal Title
 INVESTIGATIVE AND CLINICAL UROLOGY 
ISSN
 2466-0493 
Issue Date
2016
MeSH
Asian Continental Ancestry Group/statistics & numerical data ; Clinical Protocols ; Humans ; Magnetic Resonance Imaging ; Male ; Patient Selection ; Population Surveillance/methods ; Prostate-Specific Antigen/blood ; Prostatic Neoplasms/diagnosis* ; Prostatic Neoplasms/ethnology ; Prostatic Neoplasms/therapy* ; Watchful Waiting*
Keywords
Prostatectomy ; Prostatic neoplasms ; Watchful waiting
Abstract
Active surveillance (AS) is a management strategy involving close monitoring the course of disease with the expectation to intervene if the cancer progress, in a super-selected group of low-risk prostate cancer (PCa) patients. Determining AS candidates should be based on careful individualized weighing of numerous factors: life expectancy, general health condition, disease characteristics, potential side effects of treatment, and patient preference. Several protocols have been developed to determine insignificant PCa for choosing ideal AS candidates. Results regarding disease reclassification during AS have been also reported. In an effort to enhance accuracy during selection of AS candidate, there were several reports on using magnetic resonance imaging for prediction of insignificant PCa. Currently, there is an urgent need for further clinical studies regarding the criteria for recommending AS, the criteria for reclassification on AS, and the schedule for AS. Considering the racial differences in behavior of PCa between Western and Asian populations, more stringent AS protocols for Asian patients should be established from additional, well-designed, large clinical studies.
Files in This Item:
T201602116.pdf Download
DOI
10.4111/icu.2016.57.1.14
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Urology (비뇨의학교실) > 1. Journal Papers
Yonsei Authors
Lee, Seung Hwan(이승환) ORCID logo https://orcid.org/0000-0001-7358-8544
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/147118
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