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Cited 12 times in

Long-term Clinical Course of Post-infectious Irritable Bowel Syndrome After Shigellosis: A 10-year Follow-up Study.

DC FieldValueLanguage
dc.contributor.author김지현-
dc.contributor.author김현창-
dc.contributor.author박재준-
dc.contributor.author박효진-
dc.contributor.author윤영훈-
dc.contributor.author임현철-
dc.date.accessioned2017-02-27T08:12:36Z-
dc.date.available2017-02-27T08:12:36Z-
dc.date.issued2016-
dc.identifier.issn2093-0879-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/147114-
dc.description.abstractBACKGROUND/AIMS: A limited number of studies are available regarding the long-term natural history of post-infectious irritable bowel syndrome (PI-IBS). We aimed to investigate the long-term clinical course of PI-IBS. METHODS: A prospective cohort study was conducted from a 2001 shigellosis outbreak in a Korean hospital with about 2000 employees. A cohort of 124 hospital employees who were infected by Shigella sonnei due to contaminated food in the cafeteria, and 105 sex- and age-matched, non-infected, controls were serially followed for their bowel symptoms by questionnaire surveys for 10 years. RESULTS: The Shigella -infected cohort showed significantly higher odds ratio for irritable bowel syndrome (IBS) at 1-year (11.90; 95% CI, 1.49-95.58) and 3-year (3.93; 95% CI, 1.20-12.86) follow-up, compared to their controls. However, corresponding odds ratio for PI-IBS was not significantly increased at 5-year (1.88; 95% CI, 0.64-5.54) and 8-year (1.87; 95% CI, 0.62-5.19) follow-up. At 10-year follow-up survey, the prevalence of IBS was similar for the Shigella -infected cohort and their controls (23.3% versus 19.7%, P = 0.703). Risk factors which were independently associated with PI-IBS among the Shigella -infected cohort included younger age, previous history of functional bowel disorder, and longer duration of diarrhea at baseline. CONCLUSIONS: Patients who were infected by Shigella sonnei experienced significantly increased risk of IBS until 3 years after shigellosis, and modestly increased risk until 8 years, but showed similar risk of IBS with uninfected controls at 10 years post-infection. PI-IBS is quite a chronic disorder, and follows a long-term natural course.-
dc.description.statementOfResponsibilityopen-
dc.format.extent490~496-
dc.languageKorean-
dc.publisherKorean Society of Neurogastroenterology and Motility-
dc.relation.isPartOfJOURNAL OF NEUROGASTROENTEROLOGY AND MOTILITY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleLong-term Clinical Course of Post-infectious Irritable Bowel Syndrome After Shigellosis: A 10-year Follow-up Study.-
dc.typeArticle-
dc.publisher.locationKorea-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Internal Medicine-
dc.contributor.googleauthorYoung Hoon Youn-
dc.contributor.googleauthorHyeon Chang Kim-
dc.contributor.googleauthorHyun Chul Lim-
dc.contributor.googleauthorJae Jun Park-
dc.contributor.googleauthorJie-Hyun Kim-
dc.contributor.googleauthorHyojin Park-
dc.identifier.doi10.5056/jnm15157-
dc.contributor.localIdA00996-
dc.contributor.localIdA01142-
dc.contributor.localIdA01636-
dc.contributor.localIdA01774-
dc.contributor.localIdA02583-
dc.contributor.localIdA03418-
dc.relation.journalcodeJ01623-
dc.identifier.eissn2093-0887-
dc.relation.journalsince2010~-
dc.identifier.pmid26908484-
dc.relation.journalbefore~2009 Korean Journal of Neurogastroenterology and Motility (대한소화관운동학회지)-
dc.subject.keywordCohort-
dc.subject.keywordDysentery-
dc.subject.keywordIrritable bowel syndrome-
dc.subject.keywordPrognosis-
dc.subject.keywordShigella-
dc.contributor.alternativeNameKim, Ji Hyun-
dc.contributor.alternativeNameKim, Hyeon Chang-
dc.contributor.alternativeNamePark, Jae Jun-
dc.contributor.alternativeNamePark, Hyo Jin-
dc.contributor.alternativeNameYoun, Young Hoon-
dc.contributor.alternativeNameLim, Hyun Chul-
dc.contributor.affiliatedAuthorKim, Ji Hyun-
dc.contributor.affiliatedAuthorKim, Hyeon Chang-
dc.contributor.affiliatedAuthorPark, Jae Jun-
dc.contributor.affiliatedAuthorPark, Hyo Jin-
dc.contributor.affiliatedAuthorYoun, Young Hoon-
dc.contributor.affiliatedAuthorLim, Hyun Chul-
dc.citation.volume22-
dc.citation.number3-
dc.citation.startPage490-
dc.citation.endPage496-
dc.identifier.bibliographicCitationJOURNAL OF NEUROGASTROENTEROLOGY AND MOTILITY, Vol.22(3) : 490-496, 2016-
dc.date.modified2017-02-24-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Preventive Medicine and Public Health (예방의학교실) > 1. Journal Papers

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